Comportamiento de la acalasia en la provincia de Camagüey / Behavior of achalasia in Camagüey province

Fundamento: la acalasia es una enfermedad degenerativa, incurable, progresiva y poco frecuente. La acalasia primaria, idiopática o clásica trata de un trastorno de la motilidad esofágica, que combina una falta de peristaltismo del esófago (aperistalsis) con una relajación incompleta del esfínter esofágico inferior.Objetivo: describir el comportamiento de la acalasia en la provincia Camagüey.Métodos: se realizó un estudio descriptivo, de corte transversal y prospectivo. El universo de estudio se constituyó por 19 pacientes. Los datos se plasmaron en una ficha de recolección. La información se recopiló en una base de datos en Microsoft Excel 12.0. Los datos se procesaron con el sistema estadístico SPSS 11.0, se determinaron los porcentajes en el estudio. Para mejor comprensión la información se mostró en tablas.Resultados: prevalecieron los pacientes del sexo femenino, con un 68,4 porciento y las edades entre 60-69 años, con un 47,4 porciento. Todos los pacientes presentaron disfagia. Se halló un predominio de pacientes con acalasia clasificada como grado II, con un total de 11 pacientes que representa el 57,9 porciento.Conclusiones: hubo un predominio de pacientes del sexo femenino y con edades entre 60-69 años. Todos los pacientes refirieron disfagia y la acalasia moderada (grado II) fue la más frecuente(AU)

Background: achalasia is a degenerative incurable, progressive and infrequent disease. Primary, idiopathic, or classical achalasia treats an esophageal motility disorder, which combines a lack of esophageal peristalsis (aperistalsis) with incomplete relaxation of the lower esophageal sphincter.Objective: to describe the behavior of achalasia in Camagüey province.Methods: a descriptive, longitudinal, cross-sectional and prospective study was conducted. The universe of study was composed of 19 patients. The data were captured in a collection form. The information was compiled in a database in Microsoft Excel 12.0. Data were processed using the statistical system SPSS 11.0. The percentages were determined in the study. For a better understanding the information was shown in tables.Results: female patients prevailed, with 68,4 percent and ages between 60-69 years, with 47,4 percent. All patients had dysphagia. A predominance of patients with grade II-classified achalasia was found, with a total of 11 patients, representing 57,9 percent.Conclusions: there was a predominance of female patients aged 60-69 years. All patients reported dysphagia and moderate (grade II) achalasia was the most frequent(AU)

Socio-economic status and lifestyle factors are associated with achalasia risk: A population-based case-control study.

AIM: To evaluate the association between various lifestyle factors and achalasia risk. METHODS: A population-based case-control study was conducted in Northern Ireland, including n = 151 achalasia cases and n = 117 age- and sex-matched controls. Lifestyle factors were assessed via a face-to-face structured interview. The association between achalasia and lifestyle factors was assessed by unconditional logistic regression, to produce odds ratios (OR) and 95% confidence interval (CI). RESULTS: Individuals who had low-class occupations were at the highest risk of achalasia (OR = 1.88, 95%CI: 1.02-3.45), inferring that high-class occupation holders have a reduced risk of achalasia. A history of foreign travel, a lifestyle factor linked to upper socio-economic class, was also associated with a reduced risk of achalasia (OR = 0.59, 95%CI: 0.35-0.99). Smoking and alcohol consumption carried significantly reduced risks of achalasia, even after adjustment for socio-economic status. The presence of pets in the house was associated with a two-fold increased risk of achalasia (OR = 2.00, 95%CI: 1.17-3.42). No childhood household factors were associated with achalasia risk. CONCLUSION: Achalasia is a disease of inequality, and individuals from low socio-economic backgrounds are at highest risk. This does not appear to be due to corresponding alcohol and smoking behaviours. An observed positive association between pet ownership and achalasia risk suggests an interaction between endotoxin and viral infection exposure in achalasia aetiology.