RESUMO
No disponible
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Klebsiella pneumoniae/isolamento & purificação , Klebsiella pneumoniae/patogenicidade , Abscesso Hepático/complicações , Abscesso Hepático/diagnóstico , Abscesso Hepático/microbiologia , Adenoma Viloso/complicações , Adenoma Viloso/diagnóstico , Adenoma Viloso/microbiologia , Fatores de Risco , Ductos Biliares/patologia , Endoscopia/métodos , Colonoscopia/métodos , ColonoscopiaRESUMO
OBJECTIVE: We sought to identify possible diseases associated with bloodstream infections caused by new species of S. bovis group isolated in blood cultures and by studying patient records METHODS: Forty-four consecutive blood culture isolates initially designated S. bovis were further characterised using phenotypic methods Patient records were examined. RESULTS: We identified 15 Streptococcus gallolyticus subsp. gallolyticus, 24 Streptococcus gallolyticus subsp. pasteurianus, and 5 Streptococcus infantarius isolates in 44 BSI episodes. CONCLUSIONS: The association between S. bovis bacteraemia and endocarditis and/or colon carcinoma is highly dependent on the causative species. Streptococcus gallolyticus subsp. gallolyticus is a surrogate for endocarditis and/or bowel disease, whereas Streptococcus gallolyticus subsp. pasteurianus is a surrogate for hepato-biliary disease.
Assuntos
Bacteriemia/microbiologia , Neoplasias do Colo/microbiologia , Endocardite Bacteriana/microbiologia , Intestinos/microbiologia , Infecções Estreptocócicas/microbiologia , Streptococcus bovis/classificação , Adenoma Viloso/epidemiologia , Adenoma Viloso/etiologia , Adenoma Viloso/microbiologia , Idoso , Idoso de 80 Anos ou mais , Bacteriemia/epidemiologia , Doenças Biliares/epidemiologia , Doenças Biliares/microbiologia , Carcinoma Hepatocelular/epidemiologia , Carcinoma Hepatocelular/microbiologia , Causalidade , Neoplasias do Colo/epidemiologia , Neoplasias do Colo/etiologia , Pólipos do Colo/epidemiologia , Pólipos do Colo/etiologia , Pólipos do Colo/microbiologia , Comorbidade , Farmacorresistência Bacteriana Múltipla , Endocardite Bacteriana/epidemiologia , Feminino , Doenças das Valvas Cardíacas/epidemiologia , Próteses Valvulares Cardíacas , Humanos , Cirrose Hepática/epidemiologia , Cirrose Hepática/microbiologia , Neoplasias Hepáticas/epidemiologia , Neoplasias Hepáticas/microbiologia , Masculino , Pessoa de Meia-Idade , Fenótipo , Infecções Relacionadas à Prótese/epidemiologia , Infecções Relacionadas à Prótese/microbiologia , Espanha/epidemiologia , Especificidade da Espécie , Infecções Estreptocócicas/epidemiologia , Streptococcus bovis/efeitos dos fármacos , Streptococcus bovis/isolamento & purificação , Streptococcus bovis/patogenicidadeRESUMO
Bacteremia and infectious endocarditis caused by Streptococcus bovis may be related to the presence of inflammation or neoplastic lesions in the large intestine. This report describes a 46-year-old woman who presented with infectious endocarditis caused by S. bovis associated with colonic tubular-villous adenoma. Demonstration of bacterial DNA by polymerase chain reaction and identification by DNA sequencing was performed to establish the diagnosis.
Assuntos
Adenoma Viloso/microbiologia , Neoplasias do Colo/microbiologia , Infecções Estreptocócicas/microbiologia , Streptococcus bovis , Adenoma Viloso/complicações , Adenoma Viloso/diagnóstico , Neoplasias do Colo/complicações , Neoplasias do Colo/diagnóstico , DNA Bacteriano , Feminino , Humanos , Pessoa de Meia-Idade , Reação em Cadeia da Polimerase , Infecções Estreptocócicas/complicações , Infecções Estreptocócicas/diagnóstico , Streptococcus bovis/isolamento & purificaçãoRESUMO
BACKGROUND: Many studies in the literature have warned of the need for investigation of colonic lesions among patients, especially elderly ones, who have bacteremia and/or endocarditis from Streptococcus bovis. Bacteremia and infectious endocarditis from Streptococcus bovis may be related to the presence of neoplastic lesions in the large intestine and hepatic disease. AIM: This report describes a patient who presented infectious endocarditis from Streptococcus bovis associated with colonic carcinoma and tubular-villous adenomas. CONCLUSIONS: The finding of this bacterium among patients with septicemia and/or endocarditis is also related to the presence of villous or tubular-villous adenomas in the large intestine. For this reason, complete and detailed investigation of the large intestine must be performed in patients with infectious endocarditis, even in the absence of intestinal symptoms. An increased incidence of this condition or hepatic dysfunction has been reported among patients with infectious endocarditis from Streptococcus bovis. Patients with infectious endocarditis from Streptococcus bovis and normal colonoscopy may be included in the group at risk for developing colonic cancer. The knowledge that there is an association between endocarditis from Streptococcus bovis and carcinoma of the colon has important clinical implications. If the lesion can be discovered at an early stage, curative resection may become possible.
