1.
Prog Clin Biol Res
; 183: 115-24, 1985.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4048179
Assuntos
Encéfalo/metabolismo , Etanol/metabolismo , Isoquinolinas/biossíntese , Alcaloides de Salsolina/biossíntese , Animais , Encéfalo/efeitos dos fármacos , Corpo Estriado/metabolismo , Dopamina/metabolismo , Metabolismo Energético , Humanos , Levodopa/metabolismo , Levodopa/farmacologia , Masculino , Ratos , Ratos Endogâmicos
2.
Lancet
; 2(8289): 80-1, 1982 Jul 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6123816
3.
Naturwissenschaften
; 66(1): 22-7, 1979 Jan.
Artigo
em Alemão
| MEDLINE
| ID: mdl-218115
RESUMO
The formation of tetrahydro-isoquinoline alkaloids in human and animal metabolisms subsequent to alcohol consumption is reported. The spectrum of identified products ranges from simple structures such as salsolinol to the complicated skeleton of protoberberines. These substances, hitherto found exclusively in plants, interfere with the biosynthesis, biodegradation and neurotransmission of the structurally closely related biogenic amines from which they are formed, and thus affect the vegetative nervous system.
