RESUMO
We report a case of cutaneous angiolipoleiomyoma (angiomyolipoma) found on the anterior wall of the ventral part of the abdomen of a three-year-old female budgerigar (Melopsittacus undulatus). Histologic examination of the well-circumscribed, surgically removed tumour (1.5 cm in diameter) showed a benign admixed proliferation of blood vessels of different size, smooth muscle bundles, and mature adipose tissue, without evidence of malignancy. Endothelial cells of the haemangioma component were positive for claudin-5 endothelium-specific immunohistochemical marker, and the leiomyoma component was positive for α-smooth muscle actin. The differentiated lipocytes showed S-100 protein positivity. The Ki-67 labelling index was 2 to 3%. The mesenchymal tumour was negative for HMB45 melanocytic immunhistochemical marker. To the best of our knowledge, this is the first report describing a cutaneous angiolipoleiomyoma in a budgerigar with histological and immunohistochemical analyses.
Assuntos
Angiomiolipoma/veterinária , Doenças das Aves/patologia , Doenças das Aves/cirurgia , Melopsittacus , Neoplasias Cutâneas/veterinária , Actinas/metabolismo , Angiomiolipoma/patologia , Angiomiolipoma/cirurgia , Animais , Biomarcadores/metabolismo , Claudina-5/metabolismo , Imuno-Histoquímica/veterinária , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgiaRESUMO
An 11-year-old crossbred Pomeranian bitch displayed a large intramural, well-delineated uterine mass in one horn, near the junction with the uterine body. The mass was composed largely of mature adipose tissue, smooth muscle cells singly and in small clusters, anomalous medium-size and large arteries, and multifocal islands of cartilaginous and osseous tissues. Smooth muscle cells stained positively for desmin, and adipocytes and chondrocytes were positive for S-100 protein. This tumor has histologic and immunohistochemical features compatible with human uterine angiolipoleiomyoma, a rare tumor that has never been reported in the veterinary literature. This benign tumor is believed to be of a choristomatous nature.
Assuntos
Angiomiolipoma/veterinária , Doenças do Cão/patologia , Neoplasias Uterinas/veterinária , Angiomiolipoma/patologia , Angiomiolipoma/cirurgia , Animais , Doenças do Cão/cirurgia , Cães , Feminino , Histerectomia/veterinária , Imuno-Histoquímica/veterinária , Neoplasias Uterinas/patologia , Neoplasias Uterinas/cirurgiaRESUMO
A 7-month-old cat was examined for progressive abdominal distension. Radiography showed a fluid-containing cyst, which had subsequently ruptured as the result of a fall. Nephrectomy was performed, and examination revealed the coexistence of pyelocaliceal diverticula with a cystic intracapsular angiomyolipoma (mesenchymal hamartoma) in the left kidney. The diverticula were present on both cranial and caudal poles of the kidney and were lined by transitional epithelium. The hamartoma was characterized by the presence of multiple mesenchymal tissues, including thick-walled blood vessels, smooth muscle, and adipose tissue.
