RESUMO
Several ruminant species have been shown to be susceptible to Schmallenberg virus (SBV), but adult animals usually recover after showing mild or no clinical signs. However, transplacental infection can occur and lead to abortion, malformations and stillborn lambs, calves and goat kids. During November and December 2014, malformations were observed in 11 stillborn calves from two farms in the north-eastern region of Namibia. Blood samples were collected from 9 of the 11 cows that delivered stillborn and malformed calves. All these animals tested negative for Rift Valley fever, bovine viral diarrhoea and infectious bovine rhinotracheitis and were serologically positive for bluetongue virus, SBV and epizootic haemorrhagic disease virus. Clinical findings and serological results suggested that SBV may be circulating in Namibia.
Assuntos
Infecções por Bunyaviridae/veterinária , Doenças dos Bovinos/congênito , Doenças dos Bovinos/virologia , Anormalidades Musculoesqueléticas/veterinária , Orthobunyavirus/imunologia , Animais , Anticorpos Antivirais/sangue , Infecções por Bunyaviridae/congênito , Infecções por Bunyaviridae/epidemiologia , Bovinos , Doenças dos Bovinos/sangue , Doenças dos Bovinos/epidemiologia , Feminino , Anormalidades Musculoesqueléticas/virologia , Namíbia/epidemiologia , Orthobunyavirus/isolamento & purificação , Gravidez , Natimorto/veterináriaRESUMO
We present a case of congenital complete atrioventricular block in a preterm microcephalic male with multiple additional congenital anomalies, including spinal and rib abnormalities. The heart was structurally normal, and maternal tests for autoimmune disorders were negative. The brain had an immature lissencephalic appearance, suggestive of an insult early in gestation. Genetic testing was normal, virtually excluding chromosomal disorders that are known to cause lissencephaly. Viral studies were suggestive of cytomegalovirus infection during early gestation, and we believe that the patient's clinical presentation was most likely the result of an early cytomegalovirus infection. The finding of complete atrioventricular block in a patient with presumed cytomegalovirus infection would represent a very rare complication. "Isolated" complete atrioventricular block in a fetus should be considered an incentive for an extensive work-up in search for a possible etiology, rather than accepted as a final diagnosis.
