[Effect of medical treatment on the antithymic activity of schizophrenic patients' serum]. / Vliianie lekarstvennoi terapii na antitimicheskuiu aktivnost' syvorotki krovi bol'nykh shizofreniei.

In 16 schizophrenic patients treated with aminazin changes of the serum antithymic activity (ATA) were studied in relation to the drug pharmacokinetics and peculiarities of the patients' psychic status. It was found that in a part of the patients the serum ATA level sharply fell immediately after the treatment onset; the psychopathological disturbances in these patients were reduced, and the patients developed remissions of a good quality. In another part of the patients the high serum ATA remained unchanged throughout the whole observation period. These patients were resistant to the drug therapy and had pronounced schizophrenic defects in their status.