RESUMO
605 consecutive patients were patch tested with the standard CDRG test series and with a 10% alcoholic solution of propolis. Positive allergic reactions to propolis were observed in 25 patients (4.2%); thirteen of them exhibited a simultaneous positive patch test to balsam of Peru. In view of the relatively high incidence of allergic reactions and the appearance of pseudo-cross-sensitivity to another common allergen, balsam of Peru, propolis should not be used in topical medicaments or as a component of cosmetic preparations.
Assuntos
Dermatite de Contato/etiologia , Própole/imunologia , Resinas Vegetais/imunologia , Administração Cutânea , Bálsamos/imunologia , Bálsamos/uso terapêutico , Reações Cruzadas , Tchecoslováquia , Humanos , Testes do Emplastro , Própole/uso terapêuticoRESUMO
In 73 hairdressers, out of a total number of 3,300 patients, patchtests were performed using substances of a standard series. Patients of various professions excluding hairdressers and patients belonging to an age group comparable with that of hairdressers, served as two control-groups. In the group of hairdressers the most frequently seen positive reactions were against p-phenylendiamin, nickelsulfat, pellidol, cobaltchlorid, p-aminodiphenylamin, and perubalsam. The incidence of positive reactions against p-phenylendiamin and pellidol in this group was significantly higher than in the control group, whereas the higher incidence of nickelsulfat allergy in hairdressers proved not to be significant.
Assuntos
Compostos Azo/imunologia , Dermatite Ocupacional/imunologia , Eczema/induzido quimicamente , Tinturas para Cabelo/efeitos adversos , Preparações para Cabelo/efeitos adversos , Níquel/imunologia , o-Aminoazotolueno/imunologia , Adulto , Bálsamos/imunologia , Eczema/imunologia , Humanos , Pessoa de Meia-Idade , Testes do Emplastro , Fenilenodiaminas/imunologia , o-Aminoazotolueno/análogos & derivadosAssuntos
Alérgenos/isolamento & purificação , Dermatite de Contato/etiologia , Testes do Emplastro , Testes Cutâneos , Adolescente , Adulto , Idoso , Bálsamos/imunologia , Criança , Pré-Escolar , Cromo/imunologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Mercúrio/imunologia , Pessoa de Meia-Idade , Níquel/imunologiaRESUMO
Predictive tests are of value in forecasting the response of a population to a sensitizer; diagnostic testing is used to determine what substances may actually be producing dermatologic problems. Skin sensitization predictive and diagnostic data for the eleven most frequently encountered skin sensitizers in Western Europe, Canada and the United States are reviewed. These compounds include two drugs (benzocaine and neomycin), two cosmetic ingredients (p-phenylenediamine and balsam of Peru), four preservatives (formaldehyde, ethylenediamine, parabens and mercurials) and three ingredients of wearing apparel (nickel, chromium and thiram). Many of the data were collected by the North American Contact Dermatitis Group and the International Contact Dermatitis Research Group on tests with 1,200 and 4,825 dermatologic patients, respectively; the remainder were obtained by individual investigators with smaller groups of subjects. The data obtained by various investigators are discussed in relation to the factors which affect the extent and degree of sensitization which they can cause.
