1.
Xenobiotica
; 9(2): 119-27, 1979 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-433310
RESUMO
1. Two metabolites, isolated from the urine of rats dosed with bencyclane fumarate, were characterized as cis-1-benzyl-1-(3-N,N-dimethylaminopropoxy)-4-hydroxycycloheptane (metabolite I) and 1-benzyl-1-(3-N,N-dimethylaminopropoxy)-4-oxocycloheptane (metabolite II). 2. Bencyclane and the two metabolites were determined in the urine of rats and volunteers by g.l.c. Metabolite I was a major metabolite in men, being excreted in urine to the extent of 23.5% dose in the first 24 h.
Assuntos
Benciclano/metabolismo , Cicloeptanos/metabolismo , Animais , Benciclano/análogos & derivados , Benciclano/urina , Fenômenos Químicos , Química , Humanos , Masculino , Ratos , Especificidade da Espécie
2.
Boll Chim Farm
; 114(11): 663-7, 1975 Nov.
Artigo
em Italiano
| MEDLINE
| ID: mdl-1220723
3.
Pharmazie
; 30(9): 609, 1975 Sep.
Artigo
em Alemão
| MEDLINE
| ID: mdl-1187743
