[Rapunzel syndrome: Radiological diagnosis]. / Síndrome de Rapunzel: diagnóstico radiológico.

Background: Rapunzel syndrome is a rare presentation of trichobezoar, secondary to the ingestion of hair known as trichophagia. This bezoar has been found mainly in women, it invades the stomach and extends to the small intestine. Clinically, patients present weight loss and chronic obstructive symptoms at the intestinal level. A case of Rapunzel syndrome is presented. Clinical case: A 13-year-old female presented with a weight loss of 10kg in two months, chronic constipation, predominantly nocturnal vomiting, and abdominal pain of seven days' duration. Physical examination revealed decreased peristalsis and a palpable mass in the epigastrium. Laboratories taken on admission: normal blood count, kidney function tests, and liver function tests. The abdominal X-ray showed opacity in the fundus, body and gastric antrum, the abdominal ultrasound showed non-specific findings in the epigastrium, later an abdominal tomography was performed with a swallow of water-soluble contrast medium and showed occupation in the gastric lumen. She underwent exploratory laparotomy and the finding was a trichobezoar in the stomach with extension to the duodenum and part of the jejunum, which was removed without complications. The evolution of the patient was favorable. Conclusions: For the diagnosis of Rapunzel Syndrome, the use of contrast imaging studies is necessary, and the treatment of choice is surgical.

Introducción: el síndrome de Rapunzel es una presentación poco frecuente de tricobezoar, secundario a la ingesta de cabello conocida como tricofagia. Este bezoar se ha encontrado principalmente en mujeres, invade estómago y se extiende a intestino delgado. Clínicamente, los pacientes presentan pérdida de peso y síntomas crónicos de tipo obstructivo a nivel intestinal. Se presenta un caso de síndrome de Rapunzel. Caso clínico: paciente mujer de 13 años que se presenta con pérdida de peso de 10 kg en dos meses, estreñimiento crónico, vómito de predominio nocturno y dolor abdominal de siete días de evolución. A la exploración física, se encontró peristalsis disminuida y masa palpable en epigastrio. Laboratorios tomados a su ingreso: biometría hemática, pruebas de función renal y hepáticas normales. La radiografía de abdomen mostró opacidad en fundus, cuerpo y antro gástrico, la ecografía de abdomen mostró hallazgos inespecíficos en epigastrio, posteriormente se realizó tomografía abdominal con trago de medio de contraste hidrosoluble y mostró ocupación en la luz gástrica. Se sometió a laparotomía exploradora y el hallazgo fue un tricobezoar en estómago con extensión a duodeno y parte de yeyuno, fue removido sin complicaciones. La evolución de la paciente fue favorable. Conclusiones: para el diagnóstico del síndrome de Rapunzel es necesario el uso de estudios de imagen contrastados y el tratamiento de elección es quirúrgico.

Rapunzel Syndrome. A rare cause of intestinal obstruction.

BACKGROUND: Rapunzel syndrome is the formation of a trichobezoar that extends beyond the small intestine. Since its discovery few cases have been reported in the literature with variable clinical characteristics, causing important complications such as intestinal obstruction. Laparotomy is currently considered the treatment of choice. CASE REPORT: We present the clinical case of a patient who presented with recurrent peritonitis associated with a peritoneal dialysis catheter, anorexia, nausea, vomiting, without channeling or presenting evacuations, epigastric tumor, anxiety, trichotillomania and trichophagia. Rapunzel syndrome is diagnosed and admission to the operating room is decided.

ANTECEDENTES: El síndrome de Rapunzel es la formación de un tricobezoar que se extiende más allá del intestino delgado. Desde su descubrimiento, pocos casos se han reportado en la literatura y con características clínicas variables, provocando complicaciones importantes como obstrucción intestinal. Actualmente, la laparotomía se considera el tratamiento de elección. CASO CLÍNICO: Paciente de sexo femenino que acude por presentar peritonitis de repetición asociada a catéter de diálisis peritoneal, anorexia, náuseas, vómito, sin canalizar ni presentar evacuaciones, tumoración en epigastrio, ansiedad, tricotilomanía y tricofagia. Se realiza el diagnóstico de síndrome de Rapunzel y se decide su ingreso a quirófano.

Obstrução gástrica por bezoar / Gastric obstruction due to bezoar

A obstrução por bezoar é um acúmulo de material parcialmente ou não digerido no estômago. Bezoares gástricos são raros e ocorrem com mais frequência em pacientes com transtornos de comportamento, esvaziamento gástrico anormal ou após cirurgia gástrica. Podem ser assintomáticos ou apresentar sintomas como dor abdominal e vômitos incoercíveis. Podem ainda ter composições diversas e ocorrer em todas as faixas etárias. O objetivo deste relato foi demonstrar um caso de bezoar gástrico em paciente previamente submetido à cirurgia bariátrica e internado com quadro de vômitos incoercíveis e hemorragia digestiva alta, com a demonstração de que sua resolução completa ocorreu na realização da segunda endoscopia.

Bezoar obstruction is an accumulation of partially digested or undigested material in the stomach. Gastric bezoars are rare and occur more frequently in patients with behavioral disorders, abnormal gastric emptying, or after gastric surgery. They may be asymptomatic or present with symptoms such as abdominal pain and incoercible vomiting. They can have diverse compositions and occur in all age groups. The aim of this report was to demonstrate a case of gastric bezoar in a patient who previously underwent a bariatric surgery and was hospitalized with incoercible vomiting and upper gastrointestinal hemorrhage, with the demonstration that its complete resolution occurred during the second endoscopy.

Cecum perforation associated with a calcium polystyrene sulfonate bezoar - a rare entity / Perfuração do ceco associada a bezoar de poliestirenossulfonato de cálcio - uma entidade rara

Abstract Hyperkalemia is one of the most common electrolyte disorders, responsible for a high number of adverse outcomes, including life-threatening arrhythmias. Potassium binders are largely prescribed drugs used for hyperkalemia treatment but unfortunately, there are many adverse events associated with its use, mostly gastrointestinal. Identification of patients at highest risk for the serious complications associated with the current potassium binders, such as colon necrosis and perforation, could prevent fatal outcomes. The authors present a case of a 56-year-old man with secondary diabetes and chronic renal disease that was treated for hyperkalemia with Calcium Polystyrene Sulfonate (CPS). He later presented with acute abdomen due to cecum perforation and underwent ileocecal resection but ultimately died from septic shock a week later. During surgery, a solid white mass was isolated in the lumen of the colon. The mass was identified as a CPS bezoar, a rare drug-mass formed in the gastrointestinal tract that contributed to the perforation. A previous history of partial gastrectomy and vagothomy was identified as a probable risk factor for the CPS bezoar development. Hopefully, the two new potassium binders patiromer and (ZS-9) Sodium Zirconium Cyclosilicate will help treat such high-risk patients, in the near future.

Resumo A hipercalemia é um dos distúrbios eletrolíticos mais comuns, responsável por um grande número de desfechos adversos, incluindo arritmias potencialmente fatais. Quelantes de potássio são amplamente prescritos para o tratamento da hipercalemia, mas infelizmente são muitos os eventos adversos associados ao seu uso, em particular os gastrointestinais. A identificação de pacientes com risco mais elevado para complicações graves associadas aos quelantes de potássio atualmente em uso, como necrose e perfuração do cólon, pode evitar desfechos fatais. O presente artigo descreve o caso de um homem de 56 anos com diabetes secundário e doença renal crônica em tratamento por hipercalemia com poliestirenossulfonato de cálcio (PSC). Posteriormente o paciente apresentou abdômen agudo devido a perfuração do ceco e foi submetido a uma ressecção ileocecal, mas acabou indo a óbito por choque séptico uma semana mais tarde. Durante a cirurgia, uma massa branca sólida foi isolada no lúmen do cólon. A massa foi identificada como um bezoar de PSC, uma massa de fármaco de rara ocorrência formada no trato gastrointestinal que contribuiu para a perfuração. História pregressa de gastrectomia parcial e vagotomia foi identificada como provável fator de risco para o desenvolvimento do bezoar de PSC. Espera-se que os dois novos quelantes de potássio - patiromer e ciclossilicato de zircônio sódico - ajudem a tratar pacientes de alto risco em um futuro próximo.

Obstrucción intestinal por fitobezoar en una paciente con bypass gástrico laparoscópico en Y de Roux: reporte de un caso / Intestinal obstruction due to phytobezoar in a patient with laparoscopic gastric bypass in Roux-en-Y: case report

INTRODUCCIÓN: Los bezoares son una etiología infrecuente de obstrucción intestinal (OI) posterior a un bypass gástrico laparoscópico en Y de Roux (BGLYR). OBJETIVO: Describir un caso clínico de OI debido a un fitobezoar en un sitio infrecuente, en una paciente 2 años después de un BGLYR. CASO CLÍNICO: Paciente de sexo femenino con antecedente de BGLYR hace 2 años y cuadro de obstrucción intestinal causado por fitobezoar. DISCUSIÓN: Se discuten los factores que pueden contribuir a la formación del bezoar en este caso y estrategias para su prevención. Se destaca la importancia del estudio imagenológico y de la exploración quirúrgica oportuna.

BACKGROUND: Bezoars are an infrequent aetiology of bowel obstruction after a laparoscopic Roux-en-Y gastric bypass (LRYGB). OBJECTIVE: To describe a clinical case of bowel obstruction due to a phytobezoar in an uncommon site, in a patient 2 years after a LRYGB. CASE REPORT: A female patient with a history of LRYGB 2 years ago and bowel obstruction due to phytobezoar. DISCUSSION: Factors that can contribute to the formation of bezoar in this case and strategies for its prevention are discussed. The importance of the imaging study and timely surgical exploration is emphasized.

[Giant Rapunzel syndrome with atypical complication. Report of a case]. / Síndrome de Rapunzel gigante con complicación atípica. Reporte de un caso.

Rapunzel syndrome is an unusual and rare form of gastric trichobezoar that extends into the small intestine. The formation is due to the continuous ingestion of hair which leads to the impaction of the hair along with mucus and food, but it is rare that gastric perforation occurs. We report the case of a female patient of 16 years of age admitted to our institution with a history of depression and clinical symptoms characterized by nausea, severe epigastralgia and pathological loss of weight. The physical examination showed a tense abdomen with a peritoneal reaction. Contrast-enhanced tomography showed a distended stomach with a heterogeneous content that extended to the duodenum, hydro pneumoperitoneum, Douglas sack bottom liquid, and it was decided to perform an exploratory laparotomy. Showed perforation in the anterior face of the stomach which is infrequent, so we proceeded to the extraction of giant trichobezoar with duodenal extension; Evolving favorably, the patient being referred to outpatient controls with psychiatry; Finally, a high endoscopy was performed at 6 months, which evidenced the scar of the surgical procedure.

Síndrome de Rapunzel gigante con complicación atípica: Reporte de un caso / Giant Rapunzel syndrome with atypical complication: Report of a case

El síndrome de Rapunzel es una forma inusual y rara de tricobezoar gástrico que se extiende al intestino delgado. La formación es debida a la ingestión continua de cabello la cual lleva a la impactación del mismo junto con moco y alimento, pero es infrecuente que se produzca perforación gástrica. Reportamos el caso de una paciente de sexo femenino de 16 años de edad admitida en nuestra institución con antecedentes de depresión y cuadro clínico caracterizado por náuseas, epigastralgia severa y pérdida patológica de peso. Al examen físico se evidenció un abdomen tenso con reacción peritoneal, la tomografía de abdomen contrastada evidenció un estomago distendido con contenido heterogéneo que se extiende hacia el duodeno, hidroneumoperitoneo y líquido en fondo de saco de Douglas, por lo que se le decidió realizar una laparotomía exploratoria que evidenció perforación en cara anterior de estómago que es una complicación infrecuente, por lo que se procedió a la extracción del tricobezoar gigante con extensión duodenal; evolucionando de forma favorable remitiéndose la paciente a controles ambulatorios con psiquiatría; finalmente se le realizó una endoscopía alta a los 6 meses que evidenció la cicatriz del procedimiento quirúrgico.

Rapunzel syndrome is an unusual and rare form of gastric trichobezoar that extends into the small intestine. The formation is due to the continuous ingestion of hair which leads to the impaction of the hair along with mucus and food, but it is rare that gastric perforation occurs. We report the case of a female patient of 16 years of age admitted to our institution with a history of depression and clinical symptoms characterized by nausea, severe epigastralgia and pathological loss of weight. The physical examination showed a tense abdomen with a peritoneal reaction. Contrast-enhanced tomography showed a distended stomach with a heterogeneous content that extended to the duodenum, hydro pneumoperitoneum, Douglas sack bottom liquid, and it was decided to perform an exploratory laparotomy. Showed perforation in the anterior face of the stomach which is infrequent, so we proceeded to the extraction of giant trichobezoar with duodenal extension; Evolving favorably, the patient being referred to outpatient controls with psychiatry; Finally, a high endoscopy was performed at 6 months, which evidenced the scar of the surgical procedure.

Cecum perforation associated with a calcium polystyrene sulfonate bezoar - a rare entity.

Hyperkalemia is one of the most common electrolyte disorders, responsible for a high number of adverse outcomes, including life-threatening arrhythmias. Potassium binders are largely prescribed drugs used for hyperkalemia treatment but unfortunately, there are many adverse events associated with its use, mostly gastrointestinal. Identification of patients at highest risk for the serious complications associated with the current potassium binders, such as colon necrosis and perforation, could prevent fatal outcomes. The authors present a case of a 56-year-old man with secondary diabetes and chronic renal disease that was treated for hyperkalemia with Calcium Polystyrene Sulfonate (CPS). He later presented with acute abdomen due to cecum perforation and underwent ileocecal resection but ultimately died from septic shock a week later. During surgery, a solid white mass was isolated in the lumen of the colon. The mass was identified as a CPS bezoar, a rare drug-mass formed in the gastrointestinal tract that contributed to the perforation. A previous history of partial gastrectomy and vagothomy was identified as a probable risk factor for the CPS bezoar development. Hopefully, the two new potassium binders patiromer and (ZS-9) Sodium Zirconium Cyclosilicate will help treat such high-risk patients, in the near future.

Surgical outcome of jejunum-jejunum intussusception secondary to Rapunzel syndrome: a case report.

BACKGROUND: Adult intestinal intussusception is a rare condition caused by the mechanical disruption of bowel motility. A bezoar is defined as indigestible material inside the gastrointestinal tract that develops into a trapped mass; the most frequent bezoar is a trichobezoar. When a trichobezoar extends into the small intestine it is defined as Rapunzel's syndrome. Literature describing complications related to this pathology remains scarce. CASE PRESENTATION: A 16-year-old Mexican girl presented to our emergency room with acute abdomen and a presumptive diagnosis of intestinal obstruction. Computed tomography was suggestive of intussusception. Surgery confirmed a jejunal-jejunal intussusception with a mass within the gastric cavity extending into her small intestine, corresponding to a trichobezoar. A manual intussusception reduction and a gastrotomy with extraction of the trichobezoar were performed. CONCLUSIONS: We present a case of a jejunum intussusception as a complication of Rapunzel syndrome. Our patient had a favorable outcome after surgical intervention with a manual intussusception reduction, with retrograde displacement of the trichobezoar into the gastric lumen, and a complete extraction through a gastrostomy. Follow-up included psychiatric evaluation.

Síndrome de Rapunzel en una adolescente: causa de suboclusión intestinal / Rapunzel syndrome in teenager: Intestinal subocclusion cause

Resumen Objetivo: Presentar un caso de síndrome de Rapunzel. Esta es una enfermedad poco frecuente que consiste en una variante de tricobezoar gástrico que se extiende hasta la segunda porción del duodeno. Caso clínico: Paciente femenina adolescente con antecedentes de atresia tricuspídea tratada quirúrgicamente. Presentó dolor abdominal de 3 días de evolución en el hipocondrio izquierdo irradiado al hipocondrio derecho, con distensión abdominal, náuseas y vómitos. Al examen físico presentó un perímetro abdominal de 58 cm y ruidos hidroaéreos disminuidos. La laparotomía exploratoria con gastrostomía anterior mostró una masa de cabellos entrelazados de aproximadamente 40 cm de longitud, compatible con tricobezoar, que se extendió desde el fondo gástrico hasta la segunda porción, llamado síndrome de Rapunzel, provocando suboclusión intestinal. Conclusión: El diagnóstico temprano permite evitar complicaciones, que pueden ser graves. Se recomienda un manejo multidisciplinario con el servicio de psiquiatría para controlar la enfermedad de base.

Abstract Aim: Present a case of Rapunzel syndrome, this is a rare disease that is a variant of gastric tricobezoar which extends to the second portion of duodenum. Case report: Female patient with tricuspid atresia treated surgically. Abdominal pain three days of evolution on the left upper quadrant radiating to the right upper quadrant with abdominal distension, nausea and vomiting. Abdominal circumference was 58 cm, decreased bowel sounds. The exploratory laparotomy presenced of a mass formed by interlocking hair, approximately 40 cm long with a compatible tricobezoar that spread from the gastric fundus to the duodenum called Rapunzel síndrome and caused partial bowel obstruction. Conclusion: Early diagnosis can prevent complications, which can be severe, a multidisciplinary management is recommended in psychiatry service to control the underlying disease.

[Rapunzel syndrome as a cause of obstruction and intestinal perforation]. / Síndrome de Rapunzel como causa de obstrucción y perforación intestinal.

The following is a case report involving a 16 year old female with trichotillomania as an antecedent. This patient presented to the Emergency Room with a chief complaint of early satiety and persistent abdominal pain for the past 3 months. However, recently her abdominal pain has worsened and it is now complicated by nausea and vomiting. The physical exam was notable for epigastric pain on deep palpation. The biochemical analysis and abdominal ultrasound were otherwise unremarkable. An esophagogastroduodenoscopy was subsequently performed where a trichobezoar was discovered. It extended from the gastric fundus to the third portion of the duodenum. A surgical extraction of the trichobezoar was then performed. The trichobezoar was found to be 130 cm in length and 8 cm wide at its most cephalad aspect. It is important to note that they also found five mall perforations throughout the duodenum and jejunum. The patient was discharged with outpatient follow up with psychiatry. In this report we describe the case of a patient with Rapunzel syndrome that was complicated by small bowel perforation and we provide a review of the salient literature concerning this syndrome and its associated complications.

[Gastric tricobezoar: a rare cause of tumoral syndrome and pyloric obstruction]. / Tricobezoar gástrico: una causa poco frecuente de síndrome tumoral y de obstrucción pilórica.

UNLABELLED: A Trichobezoar is a rare tumoral mass of the gastrointestinal tract, formed mainly from the ingestion of hair. It contains also mucus and foods debris. CASE PRESENTATION: A 22 years old female with a 10 years history of surgery secondary to gastric foreign body (trichobezoar), presents with abdominal pain, swelling, nausea and vomiting. Physical examination of the abdomen revealed a palpable mass in the epigastric and left upper quadrant regions. It was also noted areas of alopecia of the scalp. DISCUSSION: Ninety percent of the trichobezoars present in females with a high frequency between 10-19 years. The treatment of bezoars (unless small in size) is mainly surgical. A psychiatric evaluation and follow up is important after surgery hence in most cases there is a psychological disorder that lead to the ingestion of hair.

Tricobezoar / Trichobezoar

Cuando los cuerpos extraños permanecen en el tubo digestivo del hombre por largo tiempo y resisten la acción de los jugos digestivos, forman concreciones a las que se les denomina bezoares. Los bezoares pueden estar compuestos por uno o varios tipos de materia, como los pelos de las personas (tricobezoares). En este trabajo se analiza el caso de una paciente femenina, de 24 años de edad, procedencia rural, que acude a servicio de urgencias por la presencia de dolor abdominal difuso, fundamentalmente en epigastrio, y que se irradia a todo el abdomen; además presenta vómitos y diarreas que contienen pelos. La endoscopia digestiva alta evidenció un cuerpo extraño que ocupaba toda la luz gástrica. Se realizó laparotomía exploradora y gastrotomía longitudinal anterior, en la que se encontró una gran masa compacta de aspecto oscuro. El informe anatomopatológico de la pieza, describió una muestra con forma de masa alargada, compuesta por pelo procedente del cuero cabelludo(AU)

When foreign bodies remain in the human digestive tract for a long time and tolerate the digestive juices, the produce concretions called benzoars, which may be composed by one of several types of matter, by example the hairs (trichobezoars). The objective of present paper is to analyze the case of a female patient aged 24 arriving from rural zones, who came to emergency services due to a diffuse abdominal pain, mainly in epigastrium irradiating to all the abdomen; also, had vomiting and diarrheas containing hairs. The high digestive endoscopy demonstrated a foreign body occupying all the gastric lumen. An exploratory laparotomy and anterior longitudinal gastrotomy were carried out noting a large compact mass of obscure appearance. The sample anatomical-pathological report described an enlarged mass consisting of hair from the scalp(AU)

Síndrome de Rapunzel: revisão de literatura / Rapunzel syndrome: a literature review

Tricobezoar gastroduodenal é definido como o acúmulo de cabelos e pelos no trato gastrointestinal, tendo como origem a ingestão dessas substâncias. As autoras relatam o caso de um volumoso tricobezoar associado à síndrome de Rapunzel, em jovem do sexo feminino com história de tricotilofagia e emagrecimento. Foram utilizados, como base de dados, a revisão de prontuário, a avaliação dos exames realizados e o acompanhamento durante o ato operatório. Apesar de ser um caso incomum, é necessário aventar sua hipótese diagnóstica diante de uma clínica exuberante como a da referida paciente. Não somente o bezoar deve ser adequadamente tratado, mas também a causa subjacente que levou a paciente à ingestão de cabelos.

Gastroduodenal trichobezoar is the accumulation of hair inside the gastroduodenal tract, originated by the ingestion of such object. On the presented study is reported the case of a voluminous trichobezoar associated with Rapunzel's syndrome on a young female with history of trichophagia and weight loss. With this purpose, chart review, assessment of the tests, and monitoring during the surgery were used. Despite being an unusual case, it should be suspected in a clinical exuberant as the patient, and must be properly treated, not only the bezoar itself, but the underlying cause that led to the ingestion of hair.