RESUMO
CASE REPORTS: Five dogs (4 with severe carpal contracture, 1 with a chronically infected carpal joint) underwent antebrachiometacarpal arthrodesis. Excision of all carpal bones, except the accessory carpal bone, was done, either because of persistent infection or to allow the manus to be arthrodesed in a functional position. All five dogs developed varying degrees of soft tissue swelling of the surgical site following surgery. All five arthrodeses achieved complete osseous union within 4-67 weeks. The immediate postoperative distal radiometacarpal frontal plane angulation ranged from 1° to 19° (mean ± SD: 7 ± 8°). The immediate postoperative distal radiometacarpal sagittal plane angulation ranged from 6° to 26° (mean ± SD: 17 ± 9°). Plate coverage of the secured metacarpal bone(s) ranged from 75% to 87% (mean ± SD: 80 ± 4%). Infection necessitated plate removal in four dogs, 3-17 (mean ± SD: 8 ± 6) months following surgery and 0-15 (mean ± SD: 5 ± 7) weeks following radiographic documentation of complete osseous union. CONCLUSION: Despite one dog having marked elbow incongruency and degenerative joint disease and one dog having an ipsilateral radial nerve deficit, all five dogs improved and had acceptable limb function at the time of the final evaluation, which ranged from 25 to 296 (mean ± SD: 99 ± 111) weeks following surgery.
Assuntos
Artrodese/veterinária , Ossos do Carpo/cirurgia , Carpo Animal/cirurgia , Cães/cirurgia , Animais , Artrodese/efeitos adversos , Artrodese/métodos , Placas Ósseas/veterinária , Ossos do Carpo/lesões , Carpo Animal/anormalidades , Carpo Animal/lesões , Carpo Animal/microbiologia , Cães/anormalidades , Cães/lesões , Feminino , Masculino , Resultado do TratamentoRESUMO
A 6-month-old male castrated Labrador retriever was presented for coughing and forelimb lameness. Blastomyces dermatitidis was identified in cytology of sputum and synovial fluid. Repeat arthrocentesis 7 months later revealed resolution of septic arthritis. Fungal septic arthritis should be considered for cases of monoarthritis and may respond to oral itraconazole treatment.
Blastomycose carpienne intra-articulaire chez un Labrador retriever. Un Labrador retriever mâle castré âgé de 6 mois a été présenté pour une toux et une boiterie du membre antérieur. Blastomyces dermatitidis a été identifié lors d'une cytologie de l'expectoration et du liquide synovial. Une nouvelle arthrocentèse 7 mois plus tard a révélé la résolution de l'arthrite septique. L'arthrite septique fongique devrait être considérée pour les cas de mono-arthrite et elle peut réagir au traitement à l'itraconazole oral.(Traduit par Isabelle Vallières).
Assuntos
Artrite Infecciosa/veterinária , Blastomicose/veterinária , Carpo Animal/microbiologia , Doenças do Cão/microbiologia , Itraconazol/uso terapêutico , Animais , Antifúngicos/uso terapêutico , Artrite Infecciosa/tratamento farmacológico , Artrite Infecciosa/microbiologia , Artrite Infecciosa/patologia , Blastomyces/isolamento & purificação , Blastomicose/tratamento farmacológico , Blastomicose/microbiologia , Blastomicose/patologia , Carpo Animal/patologia , Doenças do Cão/tratamento farmacológico , Doenças do Cão/patologia , Cães , Masculino , Pneumonia/microbiologia , Pneumonia/veterináriaRESUMO
The localization of sialic acids and antimicrobial products (lysozyme, IgA, lactoferrin, ß-defensin 2) as well as Rab3D in the carpal glands of pig was studied by sialoglycoconjugate histochemistry and immunohistochemistry. The secretory epithelium of the carpal glands consisted of dark and clear cells. The dark cells of these glands exhibited high levels of sialoglycoconjugates, including O-acetylated sialic acids, whereas the localization of sialic acids linked to α2-3Gal1-4GlcNAc was confined to a subpopulation of the dark cells. Furthermore, all antimicrobial substances and Rab3D were mainly detectable in a subpopulation of the dark cells. The results obtained are discussed with regard to the functional significance of these glands. Our findings suggested that Rab3D is involved in the secretory regulation of sialoglycoconjugates and antimicrobial substances. These secretory products may create a defensive barrier against microbial invasion and play an essential role in the preservation of skin integrity.
Assuntos
Carpo Animal/metabolismo , Glândulas Écrinas/metabolismo , Ácidos Siálicos/metabolismo , Animais , Carpo Animal/microbiologia , Células Cultivadas , Imunidade Inata , Imunoglobulina A/metabolismo , Imuno-Histoquímica , Lactoferrina/metabolismo , Muramidase/metabolismo , Especificidade de Órgãos , Suínos , beta-Defensinas/metabolismo , Proteínas rab3 de Ligação ao GTP/metabolismoAssuntos
Artrite Infecciosa/veterinária , Doenças das Cabras/congênito , Transmissão Vertical de Doenças Infecciosas/veterinária , Infecções por Mycoplasma/veterinária , Mycoplasma agalactiae , Animais , Animais Recém-Nascidos , Artrite Infecciosa/congênito , Artrite Infecciosa/patologia , Artrite Infecciosa/transmissão , Carpo Animal/microbiologia , Carpo Animal/patologia , Feminino , Doenças das Cabras/microbiologia , Doenças das Cabras/patologia , Doenças das Cabras/transmissão , Cabras , Masculino , Infecções por Mycoplasma/congênito , Infecções por Mycoplasma/patologia , Infecções por Mycoplasma/transmissão , Gravidez , Tarso Animal/microbiologia , Tarso Animal/patologiaAssuntos
Brucella abortus/isolamento & purificação , Brucelose/veterinária , Bursite/veterinária , Carpo Animal/microbiologia , Doenças dos Cavalos/diagnóstico , Animais , Anticorpos Antibacterianos/sangue , Brucella abortus/imunologia , Brucelose/diagnóstico , Brucelose/microbiologia , Brucelose/transmissão , Bursite/diagnóstico , Bursite/microbiologia , Carpo Animal/patologia , Doenças dos Cavalos/microbiologia , Doenças dos Cavalos/transmissão , Cavalos , Masculino , NigériaRESUMO
Fifteen two- to three-week-old kids, fed artificially with goats' milk from a dairy, were found to have polyarthritis. The most affected joints were the carpals, either unilaterally or bilaterally, and in some cases the tarsal joints. Mycoplasma putrefaciens was isolated from the joints which showed an acute fibrinopurulent arthritis. No clinical mastitis was detected in the dairy.
Assuntos
Artrite Infecciosa/veterinária , Doenças das Cabras/microbiologia , Infecções por Mycoplasma/veterinária , Animais , Artrite Infecciosa/microbiologia , Artrite Infecciosa/patologia , Carpo Animal/microbiologia , Carpo Animal/patologia , Feminino , Doenças das Cabras/patologia , Cabras , Mycoplasma/isolamento & purificação , Infecções por Mycoplasma/complicações , Infecções por Mycoplasma/patologia , Líquido Sinovial/microbiologia , Tarso Animal/microbiologia , Tarso Animal/patologiaRESUMO
A debilitated adult female moose (Alces alces) shot east of the MacKenzie River, Northwest Territories, Canada, had large fluctuant masses over both carpi. Only the forelimbs were available for examination. Carpal pathology included bilateral bursitis and osteomyelitis of subjacent bone. In addition severe osteomyelitis with fractures was observed in the left lateral and right medial digits. Brucella suis biovar 4 was isolated from the right medial first phalanx. This is believed to be the first reported case of infection with this organism in a wild moose. The bacterium is common in caribou (Rangifer tarandus) in the region.
Assuntos
Brucella/isolamento & purificação , Brucelose/veterinária , Carpo Animal/patologia , Cervos , Animais , Brucelose/patologia , Bursite/patologia , Bursite/veterinária , Carpo Animal/microbiologia , Feminino , Osteomielite/patologia , Osteomielite/veterináriaRESUMO
Eight calves were exposed in an aerosol chamber to nebulized foot-and-mouth disease virus. Two control animals were exposed in a similar manner to cell culture media only. Animals were euthanized at intervals and various tissues examined by in situ hybridization using a biotinylated RNA probe corresponding to a portion of the viral gene coding for the polymerase enzyme. By this technique large amounts of viral nucleic acid were found in coronary band, interdigital cleft and tongue as early as six hours postexposure, indicating a very rapid delivery from the portal of entry to the predilection sites for lesion development. This occurred well before the onset of viremia which by virus isolation was not detectable until 30 hours postexposure. The in situ hybridization signal in these tissues decreased in intensity and extent with time to focally positive areas, occasionally surrounding a vesicle. Other epidermal sites not normally thought of as sites for foot-and-mouth lesion development, such as carpus and eyelid, also had some viral nucleic acid detectable at various time intervals. In the lung by in situ hybridization, alveolar septa had viral nucleic acid early in infection (6-18 h postexposure) while later (36-96 h postexposure), the in situ hybridization signal was prominent in alveolar macrophages.
Assuntos
Aphthovirus/fisiologia , Doenças dos Bovinos/microbiologia , Febre Aftosa/microbiologia , Animais , Aphthovirus/genética , Aphthovirus/isolamento & purificação , Carpo Animal/microbiologia , Bovinos , Doenças dos Bovinos/patologia , Pálpebras/microbiologia , Febre Aftosa/patologia , Casco e Garras/microbiologia , Casco e Garras/patologia , Pulmão/microbiologia , Pulmão/patologia , Hibridização de Ácido Nucleico , Tonsila Palatina/patologia , Sondas RNA , RNA Viral/análise , Língua/microbiologia , Língua/patologia , Viremia/microbiologia , Viremia/veterináriaRESUMO
Four groups of 8 horses each had 1 midcarpal joint injected with 33 colony-forming units (CFU) of viable Staphylococcus aureus plus: 1 ml of saline solution (group 1, control), 250 mg of polysulfated glycosaminoglycan (PSGAG, group 2), 100 mg of methylprednisolone acetate (group 3), or 20 mg of sodium hyaulronate (group 4). Horses were euthanatized, and samples were obtained on the basis of clinical signs of septic arthritis that were nonresponsive to phenylbutazone administration. One group-1 horse, all 8 group-2 horses, 3 group-3 horses, and 4 group-4 horses were culture-positive for S aureus and had clinical signs, results of synovial fluid analysis, and histopathologic findings that were consistent with sepsis. The addition of 250 mg of PSGAG increased the development of sepsis significantly (P = 0.001), compared with results in control horses. Differences in the development of sepsis between horses injected with methylprednisolone acetate or sodium hyaluronate and control horses were not significant.