RESUMO
A characteristic electrophoretic pattern of glycosaminoglycans from fluid aspirates of the postoperative maxillary cyst has been observed. This pattern, in which hyaluronic acid and heparan sulfate are the predominant glycosaminoglycans (with lesser amounts of chondroitin-4-sulfate) may faciliate preoperative diagnosis of this lesion.
Assuntos
Glicosaminoglicanos/análise , Cistos Maxilomandibulares/análise , Doenças Maxilares/metabolismo , Sulfatos de Condroitina/análise , Eletroforese em Acetato de Celulose , Exsudatos e Transudatos/análise , Heparitina Sulfato/análise , Humanos , Ácido Hialurônico/análiseRESUMO
Cyst fluids are composed of electrolytes, proteins, lipids and viscous components. These substances affect the state of jaw cysts. Jaw cysts whose inner wall layer is ciliated epithelium contain high-viscosity fluids. This study comprised 30 cases of the following types of jaw cysts: nasopalatine, mucosal and ciliated cysts of the maxilla. And the author chiefly investigated ciliated cysts of the maxilla. Their fluid contents were extracted and pre-treated for analysis. It was concluded that hyaluronidase in cyst fluids causes cyst walls to decompose hyaluronic acid in the cellular interstitium of cyst walls or in the basement membrane of the cellular layer and convert it into cyst fluid, hence it is confirmed that the main component of viscous cyst fluid is hyaluronic acid.
Assuntos
Cistos Maxilomandibulares/análise , Doenças Maxilares/metabolismo , Sulfatos de Condroitina/análise , Cromatografia Líquida de Alta Pressão , Cílios , Exsudatos e Transudatos/análise , Humanos , Ácido Hialurônico/análise , Cistos Maxilomandibulares/ultraestrutura , Espectrofotometria InfravermelhoRESUMO
It is held that cysts in jaws enlarge as the cyst fluids increase and that the intracystic fluid pressure on the jaw bones increases because of inflammation. According to this investigation, cysts enlarge in the following manner: when a cyst is infected, the cyst wall becomes almost bloodless; cell membranes of the wall are destroyed, and unsaturated fatty acids depart from the membranes; these unsaturated fatty acids generate prostaglandins and lipoperoxides which lower the reaction of cyclic AMP; the result is resorption of the jawbone; therefore, control of the cyst inflammation is the first requirement in the treatment of the cyst. For control of the inflammation, exchanges of cyst fluids for liquids, including antibiotics, were carried out once a week. As a result, the volume of cyst fluids decreased, the cysts diminished in size, and clearing tissues were scarcely seen. It can be maintained that this irrigational method is effective for the treatment of cysts in jaws.
