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1.
J Manag Care Spec Pharm ; 27(2): 157-165, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33506732

RESUMO

BACKGROUND: Cystic fibrosis (CF) patients who receive high-dose aminoglycosides can acquire inner ear damage and subsequent hearing loss. There is no current standard protocol for assessing ototoxicity in CF centers in the United States. OBJECTIVE: To evaluate the cost-effectiveness of a pharmacist-implemented routine hearing screening for ototoxicity among pediatric patients using a clinically validated tablet audiometer to allow for earlier detection of hearing loss in an exploratory analysis. METHODS: A Markov decision-analytic model was developed to assess the cost-effectiveness of implementing routine screening with monthly cycles over a 3-year time horizon. The model measured the difference in promptly detected hearing loss, delayed detected hearing loss, and undetected hearing loss, compared with current screening practices. Model inputs were obtained through a comprehensive literature review. Primary model outcomes included total health care costs and quality-adjusted life-years (QALYs) gained with a 3% yearly discount. One-way, two-way, and probabilistic sensitivity analyses were conducted to evaluate model uncertainty. RESULTS: In a hypothetical cohort of 100 patients, routine screening using a tablet audiometer increased promptly detected hearing loss by 8 patients. There was an incremental gain of 3.2 QALYs at an increased cost of $333,826 compared with current screening practices. This resulted in an incremental cost-effectiveness ratio (ICER) of $103,771 per QALY. In the 1-way sensitivity analysis, the ICER ranged between $64,345 and $258,830 per QALY. CONCLUSIONS: Using a tablet audiometer for routine hearing screening appears to be a cost-effective option at a $150,000 per QALY willingness-to-pay threshold when only considering the immediate benefits gained. This analysis did not examine the long-term effects of early detection in language development for pediatric patients. DISCLOSURES: Huang reports funding from the University of North Carolina and GlaxoSmithKline Health Outcomes Fellowship. GlaxoSmithKline had no involvement in the study creation, analysis, or manuscript composition. The other authors have nothing to disclose.


Assuntos
Aminoglicosídeos/efeitos adversos , Audiometria/economia , Fibrose Cística/tratamento farmacológico , Perda Auditiva/diagnóstico , Programas de Rastreamento/organização & administração , Aminoglicosídeos/administração & dosagem , Audiometria/instrumentação , Criança , Computadores de Mão/economia , Análise Custo-Benefício , Relação Dose-Resposta a Droga , Implementação de Plano de Saúde/economia , Implementação de Plano de Saúde/organização & administração , Perda Auditiva/induzido quimicamente , Perda Auditiva/economia , Perda Auditiva/epidemiologia , Humanos , Cadeias de Markov , Programas de Rastreamento/economia , Modelos Econômicos , Farmacêuticos/organização & administração , Anos de Vida Ajustados por Qualidade de Vida , Estados Unidos/epidemiologia
2.
Health Secur ; 18(S1): S64-S71, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32004122

RESUMO

Global health security depends on effective surveillance systems to prevent, detect, and respond to disease threats. Real-time surveillance initiatives aim to develop electronic systems to improve reporting and analysis of disease data. Sierra Leone, with the support of Global Health Security Agenda partners, developed an electronic Integrated Disease Surveillance and Response (eIDSR) system capable of mobile reporting from health facilities. We estimated the economic costs associated with rollout of health facility eIDSR in the Western Area Rural district in Sierra Leone and projected annual direct operational costs. Cost scenarios with increased transport costs, decreased use of partner personnel, and altered cellular data costs were modeled. Cost data associated with activities were retrospectively collected and were assessed across rollout phases. Costs were organized into cost categories: personnel, office operating, transport, and capital. We estimated costs by category and phase and calculated per health facility and per capita costs. The total economic cost to roll out eIDSR to the Western Area Rural district over the 14-week period was US$64,342, a per health facility cost of $1,021. Equipment for eIDSR was the primary cost driver (45.5%), followed by personnel (35.2%). Direct rollout costs were $38,059, or 59.2% of total economic costs. The projected annual direct operational costs were $14,091, or $224 per health facility. Although eIDSR equipment costs are a large portion of total costs, annual direct operational costs are projected to be minimal once the system is implemented. Our findings can be used to make decisions about establishing and maintaining electronic, real-time surveillance in Sierra Leone and other low-resource settings.


Assuntos
Controle de Doenças Transmissíveis/economia , Coleta de Dados/economia , Monitoramento Epidemiológico , Computadores de Mão/economia , Custos e Análise de Custo , Coleta de Dados/métodos , Instalações de Saúde/economia , Humanos , Vigilância em Saúde Pública/métodos , Estudos Retrospectivos , Serra Leoa/epidemiologia
3.
Med Teach ; 41(9): 1039-1044, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31131661

RESUMO

Introduction: The Objective Structured Clinical Examination (OSCE) is used globally for formative and summative purposes. The objective of this study was to examine the impact of tablet-scoring on sources of validity evidence for an Internal Medicine residency OSCE. Methods: We compared paper-scored OSCEs from 2014 to tablet-scored OSCEs in 2015 for missing data, amount of comments, and time to pass/fail decision. We then examined in 2016 the impact on learning of showing residents their score sheets and asking them to write an action plan immediately after an OSCE. Results: Tablet-scoring significantly reduced stations with missing data from 1.8 to 0.2%, and stations without comments from 42 to 28% with an increase in word count per comment. Time to official results reduced from 3 weeks to 12 h with tablet-scoring. Residents who wrote a learning plan after reviewing their OSCE score sheets were more likely (with medium to large effect sizes) to pursue further studying and/or change their behavior (e.g. history taking or physical examination) in the clinical environment. Conclusions: OSCE tablet-scoring improved many sources of validity evidence, especially educational impact with timeliness of feedback supporting a change in behavior, a hard to achieve goal of educational interventions.


Assuntos
Atitude do Pessoal de Saúde , Competência Clínica , Computadores de Mão , Avaliação Educacional/métodos , Medicina Interna/educação , Estudantes de Medicina/psicologia , Alberta , Computadores de Mão/economia , Avaliação Educacional/economia , Humanos , Internato e Residência , Aprendizagem , Faculdades de Medicina , Inquéritos e Questionários
4.
Circulation ; 136(19): 1784-1794, 2017 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-28851729

RESUMO

BACKGROUND: Asymptomatic atrial fibrillation (AF) is increasingly common in the aging population and implicated in many ischemic strokes. Earlier identification of AF with appropriate anticoagulation may decrease stroke morbidity and mortality. METHODS: We conducted a randomized controlled trial of AF screening using an AliveCor Kardia monitor attached to a WiFi-enabled iPod to obtain ECGs (iECGs) in ambulatory patients. Patients ≥65 years of age with a CHADS-VASc score ≥2 free from AF were randomized to the iECG arm or routine care (RC). iECG participants acquired iECGs twice weekly over 12 months (plus additional iECGs if symptomatic) onto a secure study server with overread by an automated AF detection algorithm and by a cardiac physiologist and/or consultant cardiologist. Time to diagnosis of AF was the primary outcome measure. The overall cost of the devices, ECG interpretation, and patient management were captured and used to generate the cost per AF diagnosis in iECG patients. Clinical events and patient attitudes/experience were also evaluated. RESULTS: We studied 1001 patients (500 iECG, 501 RC) who were 72.6±5.4 years of age; 534 were female. Mean CHADS-VASc score was 3.0 (heart failure, 1.4%; hypertension, 54%; diabetes mellitus, 30%; prior stroke/transient ischemic attack, 6.5%; arterial disease, 15.9%; all CHADS-VASc risk factors were evenly distributed between groups). Nineteen patients in the iECG group were diagnosed with AF over the 12-month study period versus 5 in the RC arm (hazard ratio, 3.9; 95% confidence interval=1.4-10.4; P=0.007) at a cost per AF diagnosis of $10 780 (£8255). There was a similar number of stroke/transient ischemic attack/systemic embolic events (6 versus 10, iECG versus RC; hazard ratio=0.61; 95% confidence interval=0.22-1.69; P=0.34). The majority of iECG patients were satisfied with the device, finding it easy to use without restricting activities or causing anxiety. CONCLUSIONS: Screening with twice-weekly single-lead iECG with remote interpretation in ambulatory patients ≥65 years of age at increased risk of stroke is significantly more likely to identify incident AF than RC over a 12-month period. This approach is also highly acceptable to this group of patients, supporting further evaluation in an appropriately powered, event-driven clinical trial. CLINICAL TRIAL REGISTRATION: URL: https://www.isrctn.com. Unique identifier: ISRCTN10709813.


Assuntos
Fibrilação Atrial/diagnóstico , Computadores de Mão , Eletrocardiografia Ambulatorial/instrumentação , Sistema de Condução Cardíaco/fisiopatologia , Frequência Cardíaca , Tecnologia de Sensoriamento Remoto/instrumentação , Telemedicina/instrumentação , Telemetria/instrumentação , Potenciais de Ação , Idoso , Algoritmos , Doenças Assintomáticas , Fibrilação Atrial/economia , Fibrilação Atrial/fisiopatologia , Computadores de Mão/economia , Análise Custo-Benefício , Eletrocardiografia Ambulatorial/economia , Desenho de Equipamento , Feminino , Custos de Cuidados de Saúde , Humanos , Masculino , Aplicativos Móveis , Valor Preditivo dos Testes , Prognóstico , Estudos Prospectivos , Tecnologia de Sensoriamento Remoto/economia , Reprodutibilidade dos Testes , Processamento de Sinais Assistido por Computador , Telemedicina/economia , Telemetria/economia , Fatores de Tempo , País de Gales
5.
Addict Behav ; 71: 111-117, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28327379

RESUMO

OBJECTIVE: Both computerised and telephone surveys have potential advantages for research data collection. The current study aimed to determine the: (i) feasibility, (ii) acceptability, and (iii) cost per completed survey of computer tablet versus telephone data collection for clients attending an outpatient drug and alcohol treatment clinic. DESIGN: Two-arm randomised controlled trial. METHOD: Clients attending a drug and alcohol outpatient clinic in New South Wales, Australia, were randomised to complete a baseline survey via computer tablet in the clinic or via telephone interview within two weeks of their appointment. All participants completed a three-month follow-up survey via telephone. RESULTS: Consent and completion rates for the baseline survey were significantly higher in the computer tablet condition. The time taken to complete the computer tablet survey was lower (11min) than the telephone condition (17min). There were no differences in the proportion of consenters or completed follow-up surveys between the two conditions at the 3-month follow-up. Acceptability was high across both modes of data collection. The cost of the computer tablet condition was $67.52 greater per completed survey than the telephone condition. CONCLUSION: There is a trade-off between computer tablet and telephone data collection. While both data collection methods were acceptable to participants, the computer tablet condition resulted in higher consent and completion rates at baseline, therefore yielding greater external validity, and was quicker for participants to complete. Telephone data collection was however, more cost-effective. Researchers should carefully consider the mode of data collection that suits individual study needs.


Assuntos
Computadores de Mão/estatística & dados numéricos , Pacientes Ambulatoriais/psicologia , Pacientes Ambulatoriais/estatística & dados numéricos , Transtornos Relacionados ao Uso de Substâncias/psicologia , Inquéritos e Questionários , Telefone/estatística & dados numéricos , Adulto , Transtornos Relacionados ao Uso de Álcool/diagnóstico , Transtornos Relacionados ao Uso de Álcool/psicologia , Análise por Conglomerados , Computadores de Mão/economia , Análise Custo-Benefício/economia , Análise Custo-Benefício/estatística & dados numéricos , Estudos de Viabilidade , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , New South Wales , Transtornos Relacionados ao Uso de Substâncias/diagnóstico , Telefone/economia
6.
Eval Program Plann ; 63: 1-6, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28279866

RESUMO

Mobile technology is opening new avenues for healthcare providers to create and implement tailored and personalized health education programs. We estimate and compare the cost of developing an i-Pad based tailored interactive multimedia intervention (TIMI) and a print based (Photonovella) intervention to increase human papillomavirus (HPV) immunization. The development costs of the interventions were calculated using a societal perspective. Direct cost included the cost of planning the study, conducting focus groups, and developing the intervention materials by the research staff. Costs also included the amount paid to the vendors who produced the TIMI and Photonovella. Micro cost data on the staff time and materials were recorded in logs for tracking personnel time, meeting time, supplies and software purchases. The costs were adjusted for inflation and reported in 2015 USD. The total cost of developing the Photonovella was $66,468 and the cost of developing the TIMI was $135,978. The amortized annual cost for the interventions calculated at a 3% discount rate and over a 7-year period was $10,669 per year for the Photonovella and $21,825 per year for the TIMI intervention. The results would inform decision makers when planning and investing in the development of interactive multimedia health interventions.


Assuntos
Computadores de Mão/economia , Educação em Saúde/economia , Educação em Saúde/métodos , Multimídia/economia , Infecções por Papillomavirus/prevenção & controle , Publicações/economia , Custos e Análise de Custo , Grupos Focais , Conhecimentos, Atitudes e Prática em Saúde , Hispânico ou Latino , Humanos , Vacinas contra Papillomavirus , Pais/psicologia , Texas
7.
Cytometry B Clin Cytom ; 92(6): 451-455, 2017 11.
Artigo em Inglês | MEDLINE | ID: mdl-25917935

RESUMO

BACKGROUND: Point-of-care (POC) CD4 T-cell counting is increasingly recognized as providing improved linkage-to-care during management of HIV infection, particularly in resource-limited settings where disease burden is highest. This study evaluated prototype POC CD4 T-cell counters from MBio Diagnostics in the context of low CD4 count, hospitalized patients in Mozambique. This study measured system performance when presented with challenging, low count samples from HIV/AIDS patients with acute illnesses resulting in hospitalization. METHODS: Forty whole blood samples were collected from donors on the medical service at Maputo Central Hospital and absolute CD4 counts were generated on the MBio CD4 system and a reference laboratory using flow cytometry. RESULTS: The mean and median CD4 counts by the flow cytometry reference were 173 and 80 cells/µL, respectively. Correlation between the MBio CD4 System and the reference was good. Bland-Altman analysis showed a mean bias of +15 cells/µL (+9 to +21 cells/µL, 95% CI), and limits of agreement of -47 to 77 cells/µL. For samples with counts >100 cells/µL (N = 14), the mean coefficient of variation was 7.3%. For samples with counts <50 cells/µL, mean absolute bias of replicate samples was 4.8 cells/µL. When two MBio readers were compared, Bland-Altman bias was -4 cells/µL (-13 to +6 cells/µL, 95% CI), and limits of agreement of -63 and +55 cells/µL. CONCLUSIONS: The MBio System holds promise as a POC system for quantitation of CD4 T cells in resource-limited settings given system throughput (80-100 cartridges/day), design simplicity, and ease-of-use. © 2015 International Clinical Cytometry Society.


Assuntos
Contagem de Linfócito CD4/instrumentação , Linfócitos T CD4-Positivos/imunologia , Citometria de Fluxo/instrumentação , Infecções por HIV/diagnóstico , Imunofenotipagem/métodos , Sistemas Automatizados de Assistência Junto ao Leito , Complexo CD3/imunologia , Linfócitos T CD4-Positivos/virologia , Estudos de Casos e Controles , Computadores de Mão/economia , Computadores de Mão/provisão & distribuição , Países em Desenvolvimento , Citometria de Fluxo/economia , Infecções por HIV/imunologia , Infecções por HIV/virologia , Humanos , Imunofenotipagem/instrumentação , Subpopulações de Linfócitos/imunologia , Subpopulações de Linfócitos/virologia , Aplicativos Móveis/economia , Aplicativos Móveis/provisão & distribuição , Moçambique , Padrões de Referência , Reprodutibilidade dos Testes
8.
Cytometry B Clin Cytom ; 92(6): 437-444, 2017 11.
Artigo em Inglês | MEDLINE | ID: mdl-27406947

RESUMO

CD4 T-cell counting was introduced in clinical laboratories shortly after the discovery of the human immune deficiency virus (HIV) in the early eighties. In western clinical laboratories, improvements in the CD4 T-cell counting methods were mainly driven by progress in the field of flow cytometry and immunology. In contrast, the development of dedicated CD4 T-cell counting technologies were needs driven. When antiretroviral treatment (ART) was made available on a large scale by international Acquired Immune Deficiency Syndrome (AIDS) relief programs to HIV+ patients living in low income countries in 2003, there was a distinct need for simplified and affordable CD4 T-cell counting technologies. The first decade of 2000, several compact flow cytometers appeared on the market, mainly to the benefit of low income countries with limited resources. More recently, however, portable point-of-care (POC) CD4 T-cell counting devices have been developed especially to improve access to affordable monitoring of HIV+ patients in low income countries. The accuracy of these POC instruments is not yet very well documented as many are still under development and clinical validation but preliminary evidence is encouraging. The new HIV treatment guidelines released by the World Health Organization in 2016 give CD4 T-cell counting a less central role in the management of HIV infection. It is, therefore, to be expected that CD4 T-cell counting will be phased out as a tool to assess eligibility of HIV+ patients for ART in the future. However, CD4 T-cell counting will remain a valuable tool for directing treatment against opportunistic infections. © 2016 International Clinical Cytometry Society.


Assuntos
Contagem de Linfócito CD4/instrumentação , Linfócitos T CD4-Positivos/imunologia , Citometria de Fluxo/instrumentação , Infecções por HIV/diagnóstico , Testes Imediatos , Fármacos Anti-HIV/uso terapêutico , Linfócitos T CD4-Positivos/virologia , Computadores de Mão/economia , Computadores de Mão/provisão & distribuição , Países em Desenvolvimento , Citometria de Fluxo/economia , HIV/efeitos dos fármacos , HIV/fisiologia , Infecções por HIV/tratamento farmacológico , Infecções por HIV/imunologia , Infecções por HIV/virologia , Humanos , Imunofenotipagem/instrumentação , Imunofenotipagem/métodos , Aplicativos Móveis/economia , Aplicativos Móveis/provisão & distribuição , Guias de Prática Clínica como Assunto
9.
Cyberpsychol Behav Soc Netw ; 19(12): 733-739, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27849356

RESUMO

This study explores whether screen shape influences smartwatch adoption by proposing an extended technology acceptance model that integrates an empirical comparison between round and square screens with utilitarian and hedonic motivations for higher usage intention. To verify the statistical validity of the proposed model, a structural equation modeling analysis is conducted on data collected from a between-subjects experiment (N = 200) in which participants trialed a smartwatch with either a round or square screen to retrieve health information cumulated from the physical activity during the experiment. Results indicate that a round screen, compared with a square screen, is more effective in promoting smartwatch adoption by enhancing the device's hedonic qualities. However, a round screen is found to reduce the controllability of the device, although such a utilitarian quality still positively influences the adoption process. Implications of the study findings and directions for future research are discussed.


Assuntos
Computadores de Mão/economia , Comportamento do Consumidor , Apresentação de Dados , Intenção , Motivação , Adolescente , Adulto , Economia , Feminino , Humanos , Masculino , Adulto Jovem
10.
High Blood Press Cardiovasc Prev ; 23(3): 187-96, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27072129

RESUMO

Electronic processes and communication technologies are more and more often employed to provide healthcare services to caregivers and their patients. Such solutions are currently referred as e-health, the most popular and widely distributed being those based on telemedicine and mobile health (m-health). A specific application of telemedicine for hypertension management is blood pressure telemonitoring (BPT), which allows remote data transmission of BP and additional information on patients' health status from their living site or from a community setting to the doctor's office or the hospital. Several randomized studies have documented a significant BP reduction with regular BPT compared to usual care, particularly in high risk hypertensive patients. Additional benefits are observed when BPT is offered under the supervision of a team of healthcare professionals, including a community pharmacist. BPT may also be provided in the context of m-health solutions, which commonly include wireless diagnostic and clinical decision support tools. M-health has the potential to promote patient's self-management, as a complement to the doctor's intervention, and encourage greater participation in medical decision making. Current statistics show that half of smartphone owners gather health information through their phone and 19 % use a health app. In case of hypertensive patients the most popular apps are those with tracking function, including BPT. Thus, e-health, and in particular BPT and m-health, are progressively gaining a key role in the management of hypertensive patients, having the potential to improve the quality of the delivered care and to more effectively prevent cardiovascular consequences of high BP.


Assuntos
Determinação da Pressão Arterial/instrumentação , Pressão Sanguínea , Computadores de Mão , Diagnóstico por Computador/instrumentação , Hipertensão/diagnóstico , Hipertensão/terapia , Aplicativos Móveis , Telemedicina/instrumentação , Terapia Assistida por Computador/instrumentação , Determinação da Pressão Arterial/economia , Serviços Comunitários de Farmácia , Computadores de Mão/economia , Análise Custo-Benefício , Prestação Integrada de Cuidados de Saúde , Diagnóstico por Computador/economia , Custos de Cuidados de Saúde , Nível de Saúde , Humanos , Hipertensão/economia , Hipertensão/fisiopatologia , Aplicativos Móveis/economia , Valor Preditivo dos Testes , Melhoria de Qualidade , Indicadores de Qualidade em Assistência à Saúde , Telemedicina/economia , Terapia Assistida por Computador/economia , Resultado do Tratamento
11.
Value Health ; 18(5): 631-7, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26297091

RESUMO

OBJECTIVE: To report the cost-effectiveness of a tailored handheld computerized procedural preparation and distraction intervention (Ditto) used during pediatric burn wound care in comparison to standard practice. METHODS: An economic evaluation was performed alongside a randomized controlled trial of 75 children aged 4 to 13 years who presented with a burn to the Royal Children's Hospital, Brisbane, Australia. Participants were randomized to either the Ditto intervention (n = 35) or standard practice (n = 40) to measure the effect of the intervention on days taken for burns to re-epithelialize. Direct medical, direct nonmedical, and indirect cost data during burn re-epithelialization were extracted from the randomized controlled trial data and combined with scar management cost data obtained retrospectively from medical charts. Nonparametric bootstrapping was used to estimate statistical uncertainty in cost and effect differences and cost-effectiveness ratios. RESULTS: On average, the Ditto intervention reduced the time to re-epithelialize by 3 days at AU$194 less cost for each patient compared with standard practice. The incremental cost-effectiveness plane showed that 78% of the simulated results were within the more effective and less costly quadrant and 22% were in the more effective and more costly quadrant, suggesting a 78% probability that the Ditto intervention dominates standard practice (i.e., cost-saving). At a willingness-to-pay threshold of AU$120, there is a 95% probability that the Ditto intervention is cost-effective (or cost-saving) against standard care. CONCLUSIONS: This economic evaluation showed the Ditto intervention to be highly cost-effective against standard practice at a minimal cost for the significant benefits gained, supporting the implementation of the Ditto intervention during burn wound care.


Assuntos
Queimaduras/economia , Queimaduras/terapia , Custos Hospitalares , Hospitais Pediátricos/economia , Manejo da Dor/economia , Terapia Assistida por Computador/economia , Adolescente , Fatores Etários , Bandagens/economia , Queimaduras/diagnóstico , Criança , Pré-Escolar , Cicatriz/diagnóstico , Cicatriz/economia , Cicatriz/terapia , Simulação por Computador , Computadores de Mão/economia , Análise Custo-Benefício , Feminino , Humanos , Masculino , Modelos Econômicos , Manejo da Dor/instrumentação , Poliésteres/economia , Poliésteres/uso terapêutico , Polietilenos/economia , Polietilenos/uso terapêutico , Avaliação de Programas e Projetos de Saúde , Estudos Prospectivos , Queensland , Reepitelização , Estudos Retrospectivos , Silicones/economia , Silicones/uso terapêutico , Terapia Assistida por Computador/instrumentação , Resultado do Tratamento
12.
ACS Nano ; 9(8): 7857-66, 2015 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-26159546

RESUMO

Standard microplate based enzyme-linked immunosorbent assays (ELISA) are widely utilized for various nanomedicine, molecular sensing, and disease screening applications, and this multiwell plate batched analysis dramatically reduces diagnosis costs per patient compared to nonbatched or nonstandard tests. However, their use in resource-limited and field-settings is inhibited by the necessity for relatively large and expensive readout instruments. To mitigate this problem, we created a hand-held and cost-effective cellphone-based colorimetric microplate reader, which uses a 3D-printed opto-mechanical attachment to hold and illuminate a 96-well plate using a light-emitting-diode (LED) array. This LED light is transmitted through each well, and is then collected via 96 individual optical fibers. Captured images of this fiber-bundle are transmitted to our servers through a custom-designed app for processing using a machine learning algorithm, yielding diagnostic results, which are delivered to the user within ∼1 min per 96-well plate, and are visualized using the same app. We successfully tested this mobile platform in a clinical microbiology laboratory using FDA-approved mumps IgG, measles IgG, and herpes simplex virus IgG (HSV-1 and HSV-2) ELISA tests using a total of 567 and 571 patient samples for training and blind testing, respectively, and achieved an accuracy of 99.6%, 98.6%, 99.4%, and 99.4% for mumps, measles, HSV-1, and HSV-2 tests, respectively. This cost-effective and hand-held platform could assist health-care professionals to perform high-throughput disease screening or tracking of vaccination campaigns at the point-of-care, even in resource-poor and field-settings. Also, its intrinsic wireless connectivity can serve epidemiological studies, generating spatiotemporal maps of disease prevalence and immunity.


Assuntos
Anticorpos Antivirais/sangue , Computadores de Mão/economia , Ensaio de Imunoadsorção Enzimática/métodos , Imunoglobulina G/sangue , Sistemas Automatizados de Assistência Junto ao Leito/economia , Telefone Celular/instrumentação , Colorimetria/economia , Colorimetria/instrumentação , Colorimetria/métodos , Ensaio de Imunoadsorção Enzimática/economia , Ensaio de Imunoadsorção Enzimática/instrumentação , Herpes Genital/sangue , Herpes Genital/diagnóstico , Herpes Genital/imunologia , Herpes Simples/sangue , Herpes Simples/diagnóstico , Herpes Simples/imunologia , Humanos , Aprendizado de Máquina , Sarampo/sangue , Sarampo/diagnóstico , Sarampo/imunologia , Aplicativos Móveis , Caxumba/sangue , Caxumba/diagnóstico , Caxumba/imunologia , Fibras Ópticas , Testes Imediatos , Sensibilidade e Especificidade
13.
PLoS One ; 10(6): e0131584, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26110865

RESUMO

Illegal hunting (poaching) is a global threat to wildlife. Anti-poaching initiatives are making increasing use of technology, such as infrared thermography (IRT), to support traditional foot and vehicle patrols. To date, the effectiveness of IRT for poacher location has not been tested under field conditions, where thermal signatures are often complex. Here, we test the hypothesis that IRT will increase the distance over which a poacher hiding in African scrub bushveldt can be detected relative to a conventional flashlight. We also test whether any increase in effectiveness is related to the cost and complexity of the equipment by comparing comparatively expensive (22,000 USD) and relatively inexpensive (2000 USD) IRT devices. To test these hypotheses we employ a controlled, fully randomised, double-blind procedure to find a poacher in nocturnal field conditions in African bushveldt. Each of our 27 volunteer observers walked three times along a pathway using one detection technology on each pass in randomised order. They searched a prescribed search area of bushveldt within which the target was hiding. Hiding locations were pre-determined, randomised, and changed with each pass. Distances of first detection and positive detection were noted. All technologies could be used to detect the target. Average first detection distance for flashlight was 37.3 m, improving by 19.8 m to 57.1 m using LIRT and by a further 11.2m to 68.3m using HIRT. Although detection distances were significantly greater for both IRTs compared to flashlight, there was no significant difference between LIRT and HIRT. False detection rates were low and there was no significant association between technology and accuracy of detection. Although IRT technology should ideally be tested in the specific environment intended before significant investment is made, we conclude that IRT technology is promising for anti-poaching patrols and that for this purpose low cost IRT units are as effective as units ten times more expensive.


Assuntos
Computadores de Mão , Comportamento Criminoso , Espécies em Perigo de Extinção , Pradaria , Atividades Humanas , Termografia , Adulto , Animais , Animais Selvagens , Computadores de Mão/economia , Conservação dos Recursos Naturais/métodos , Análise Custo-Benefício , Método Duplo-Cego , Armas de Fogo , Humanos , Raios Infravermelhos , Masculino , Aplicativos Móveis/economia , Parques Recreativos , Distribuição Aleatória , África do Sul , Termografia/economia , Termografia/instrumentação , Termografia/métodos
14.
Radiol Technol ; 86(5): 490-8, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25995401

RESUMO

BACKGROUND: Developing countries have far fewer trained radiography professionals than developed countries, which exacerbates the limited access to imaging services. The lack of trained radiographers reflects, in part, limited availability of radiographer-specific educational resources. Historically, organizations that provided such resources in the developing world faced challenges related to the limited stock of current materials as well as expenses associated with shipping and delivery. METHODS: Four mobile electronic devices (MEDs) were loaded with educational content (e-books, PDFs, and digital applications) spanning major radiography topics. The MEDs were distributed to 4 imaging departments in Ghana, India, Nepal, and Nigeria based on evidence of need for radiography-specific resources, as revealed by survey responses. A cost comparison of postal delivery vs digital delivery of educational content was performed. The effectiveness of delivering additional content via Wi-Fi transmission also was evaluated. Feedback was solicited on users' experience with the MEDs as a delivery tool for educational content. RESULTS: An initial average per e-book expense of $30.05, which included the cost of the device, was calculated for the MED delivery method compared with $15.56 for postal delivery of printed materials. The cost of the MED delivery method was reduced to an average of $10.05 for subsequent e-book deliveries. Additional content was successfully delivered via Wi-Fi transmission to all recipients during the 3-month follow-up period. Overall user feedback on the experience was positive, and ideas for enhancing the MED-based method were identified. CONCLUSION: Using MEDs to deliver radiography-specific educational content appears to be more cost effective than postal delivery of printed materials on a long-term basis. MEDs are more efficient for providing updates to educational materials. Customization of content to department needs, and using projector devices could enhance the usefulness of MEDs for radiographer training.


Assuntos
Instrução por Computador/economia , Computadores de Mão/economia , Países em Desenvolvimento , Diagnóstico por Imagem/economia , Radiologia/economia , Radiologia/educação , Instrução por Computador/métodos , Análise Custo-Benefício , Avaliação Educacional
15.
Nurse Educ Today ; 35(5): 663-72, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25665926

RESUMO

BACKGROUND: The International Council of Nurses (ICN), Sigma Theta Tau International Honor Society of Nursing (STTI), and many National Nurses Associations (NNAs), have called for the integration of information technology into nursing curriculums to prepare nursing students for the current practice environment which requires access to large amounts of information to provide evidence-based patient care. Nurse educators have begun to address the integration of technology in nursing curriculum, but are the available tools, in particular, mobile devices loaded with informational applications, being maximized? Literature Review Aims The aims of this literature review are to 1) explore the literature written on the use of mobile technology in nursing education; 2) methodically discuss the benefits and concerns involved in using mobile technology in nursing education; and 3) consider strategies for enhancing the use of mobile technology in nursing education. Review Methods A search was conducted on the use of mobile technology in nursing programs in Academic Search Complete, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Medline with Full Text, and Medline Journals. Seventeen studies, published within the last five years in peer-reviewed journals regarding the mobile technology in nursing programs were identified. Findings Although many nursing programs have implemented the use of mobile technology in the clinical, classroom, and laboratory settings, more work needs to be done to overcome the concerns related to: cost, lack of IT support, lack of faculty acceptance and role-modeling, lack of structured assignments and/or activities designed to encourage the implementation of mobile devices; and constraints on their use in clinical settings. CONCLUSION: While much has been done to incorporate the use of mobile technology in nursing curriculum, nurse educators are encouraged to develop strategies to overcome the concerns noted. Possible strategies to overcome the concerns are discussed herein.


Assuntos
Computadores de Mão/estatística & dados numéricos , Educação em Enfermagem , Informática Médica/estatística & dados numéricos , Atitude Frente aos Computadores , Computadores de Mão/economia , Currículo , Docentes de Enfermagem , Informática Médica/economia , Estudantes de Enfermagem
16.
Augment Altern Commun ; 31(1): 27-36, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25685882

RESUMO

Families of children with communication disabilities were surveyed to explore wants and preferences relative to mobile media technology, including iPads, as a form of augmentative and alternative communication (AAC). The families surveyed reported wanting information and support from professionals, including speech language pathologists (SLPs), who are knowledgeable about AAC. These families wanted devices to meet their children's individual needs and reported that ease of use and affordability were the most influential characteristics in the purchase of mobile media devices and communication applications. SLPs who understand family decision making can utilize collaborative clinical decision making that respects families' wants and needs, while also focusing on device feature matching and family education.


Assuntos
Auxiliares de Comunicação para Pessoas com Deficiência , Transtornos da Comunicação/reabilitação , Computadores de Mão , Comportamento do Consumidor , Família , Aplicativos Móveis , Adulto , Paralisia Cerebral/complicações , Paralisia Cerebral/reabilitação , Auxiliares de Comunicação para Pessoas com Deficiência/economia , Transtornos da Comunicação/etiologia , Computadores de Mão/economia , Síndrome de Down/complicações , Síndrome de Down/reabilitação , Apoio Financeiro , Humanos , Pessoa de Meia-Idade , Aplicativos Móveis/economia , Avaliação das Necessidades , Adulto Jovem
17.
Methods Mol Biol ; 1256: 459-96, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25626557

RESUMO

Smartphones of the latest generation featuring advanced multicore processors, dedicated microchips for graphics, high-resolution cameras, and innovative operating systems provide a portable platform for running sophisticated medical screening software and delivering point-of-care patient diagnostic services at a very low cost. In this chapter, we present a smartphone digital dermoscopy application that can analyze high-resolution images of skin lesions and provide the user with feedback about the likelihood of malignancy. The same basic procedure has been adapted to evaluate other skin lesions, such as the flesh-eating bacterial disease known as Buruli ulcer. When implemented on the iPhone, the accuracy and speed achieved by this application are comparable to that of a desktop computer, demonstrating that smartphone applications can combine portability and low cost with high performance. Thus, smartphone-based systems can be used as assistive devices by primary care physicians during routine office visits, and they can have a significant impact in underserved areas and in developing countries, where health-care infrastructure is limited.


Assuntos
Úlcera de Buruli/diagnóstico , Telefone Celular/instrumentação , Dermoscopia/instrumentação , Melanoma/diagnóstico , Neoplasias Cutâneas/diagnóstico , Telemedicina/instrumentação , Algoritmos , Úlcera de Buruli/microbiologia , Úlcera de Buruli/patologia , Telefone Celular/economia , Computadores de Mão/economia , Dermoscopia/economia , Países em Desenvolvimento , Diagnóstico por Imagem , Humanos , Interpretação de Imagem Assistida por Computador , Internet , Melanoma/patologia , Sistemas Automatizados de Assistência Junto ao Leito , Neoplasias Cutâneas/patologia , Software , Telemedicina/economia , Telemedicina/métodos
18.
Curationis ; 38(2): e1-e10, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26852423

RESUMO

BACKGROUND: Promoting the quality and effectiveness of nursing education is an important factor, given the increased demand for nursing professionals. It is important to establish learning environments that provide personalised guidance and feedback to students about their practical skills and application of their theoretical knowledge. OBJECTIVE: To explore and describe the knowledge and points of view of students and educators about introduction of new technologies into an undergraduate nursing programme. METHOD: The qualitative design used Tesch's (1990) steps of descriptive data analysis to complete thematic analysis of the data collected in focus group discussions (FGDs) and individual interviews to identify themes. RESULTS: Themes identified from the students' FGDs and individual interviews included: mobile devices as a communication tool; email, WhatsApp and Facebook as methods of communication; WhatsApp as a method of communication; nurses as role-models in the clinical setting; setting personal boundaries; and impact of mobile devices in clinical practice on professionalism. Themes identified from the FGD, individual interviews and a discussion session held with educators included: peer learning via mobile devices; email, WhatsApp and Facebook as methods of communication; the mobile device as a positive learning method; students need practical guidance; and ethical concerns in clinical facilities about Internet access and use of mobile devices. CONCLUSION: The research project established an understanding of the knowledge and points of view of students and educators regarding introduction of new technologies into an undergraduate nursing programme with the aim of enhancing integration of theory and clinical practice through use of mobile devices.


Assuntos
Computadores de Mão/economia , Bacharelado em Enfermagem/métodos , Percepção , Estudantes de Enfermagem/psicologia , Computadores de Mão/normas , Grupos Focais , Humanos , Cuidados de Enfermagem/métodos , Cuidados de Enfermagem/normas , Pesquisa Qualitativa , Mídias Sociais
19.
Stud Health Technol Inform ; 206: 20-8, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25365668

RESUMO

The purpose of this study is to develop an understanding in the use of mobile devices in administering telemedicine services within the public health care sector of South Africa. An online questionnaire was developed and distributed amongst medical officers, specialists, students and medical staff of one of the health districts of South Africa. This paper describes the design of the questionnaire as well as the most significant outcomes. Results are presented in terms of reasons why healthcare workers use mobile devices, as well as perceptions in terms of transmission security and quality of transmitted information.


Assuntos
Telefone Celular/estatística & dados numéricos , Computadores de Mão/estatística & dados numéricos , Prática de Saúde Pública/economia , Prática de Saúde Pública/estatística & dados numéricos , Telemedicina/instrumentação , Telemedicina/estatística & dados numéricos , Telefone Celular/economia , Computadores de Mão/economia , África do Sul , Inquéritos e Questionários , Telemedicina/economia
20.
BMC Med Inform Decis Mak ; 14: 100, 2014 Nov 25.
Artigo em Inglês | MEDLINE | ID: mdl-25421099

RESUMO

BACKGROUND: Excessive venipunctures are a significant problem both in emergency rooms and during hospital stays. Near-infrared (NIR) illumination devices improve venipuncture success rate but their usage is limited by their availability and economic cost. The objectives of this study were to develop a low-cost NIR spectroscopy prototype from a standard mobile device, to evaluate its efficacy and acceptance as an educational tool, and in a clinical setting. METHODS: Through a user-centric design process a prototype device was developed. Its educational efficacy was evaluated through a non-invasive, observational study (20 student clinicians, 25 subjects) and its acceptance was assessed using quantitative and qualitative analysis. A smaller clinical trial was performed by a group of 4 medical professionals over a period of 6 weeks that involved 64 patients. RESULTS: The prototype enables real-time visualization of peripheral veins on a variety of Android-based devices. The prototype was 35.2% more successful in visualizing and locating veins (n = 500 attempts) than the nursing students. The acceptance assessment revealed high perception of usefulness, satisfaction, and ease of use. In the clinical trial, 1.6 (SD 1.3) additional veins per patient were identified compared with the traditional visualization methods. CONCLUSIONS: To the best of our knowledge this is the first study that describes the design, feasibility and application of an NIR spectroscopy prototype developed on a standard mobile device.


Assuntos
Computadores de Mão/tendências , Educação em Enfermagem/métodos , Aplicativos Móveis/tendências , Flebotomia/enfermagem , Espectroscopia de Luz Próxima ao Infravermelho/métodos , Dispositivos de Acesso Vascular/tendências , Sistemas Computacionais , Computadores de Mão/economia , Educação em Enfermagem/estatística & dados numéricos , Desenho de Equipamento , Estudos de Viabilidade , Humanos , Aplicativos Móveis/economia , Flebotomia/estatística & dados numéricos , Eslovênia , Espectroscopia de Luz Próxima ao Infravermelho/economia , Espectroscopia de Luz Próxima ao Infravermelho/instrumentação , Dispositivos de Acesso Vascular/economia
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