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1.
Probl Radiac Med Radiobiol ; 26: 199-218, 2021 Dec.
Artigo em Inglês, Ucraniano | MEDLINE | ID: mdl-34965549

RESUMO

Objective of research is to improve the electronic database of WBC measurements dated 1986 by inputting of newinformation from paper carriers, reconstruction of information gaps, verification and analysis of new entered data,revision of internal exposure doses that are based on results of WBC measurements dated 1986. MATERIALS AND METHODS: In 2013-2015 during a revision of databases (DB) of WBC measurements results dated1986-2014, it was discovered a great amount of paper carriers with information about WBC measurements, includ-ing the ones dated 1986, that were not inputted to the electronic DB. The paper carriers were systematized andordered by the following indicators: place of residence of a person and place of WBC measurement, institution andoperator that made the measurement, measurement device and date of measurement. For a comfortable inputtingof the information to the electronic DB, it was additionally created a form which exists as an option in existing program complex Silbody (Version 19.0.9). In the revised DB of WBC measurements dated 1986 internal exposure dosesfrom radio-cesium of Chornobyl origin were computed based on an ecological and dosimetric model for radio-cesiummigration in environment and a model for radio-cesium metabolism in human body. In the work, mathematical andstatistical methods of research were used. RESULTS: In 2019-2021 additionally 35,319 notes were inputted to the electronic DB of WBC measurement dated1986, and as a result its volume increased in 2.2 times. Mostly those are data on results concerning residents of Kyiv,Zhytomyr, Donetsk, Cherkasy, Odessa, Ivano-Frankivsk, and Rivne Oblasts. It was established the information onmeasurement devices and respectively on the minimal detected activity (MDA) for 27,119 notes (76.7 % of all newentered). Information is reconstructed about the body mass of all persons under investigation. Evaluation is madefor values of intake of incorporated radionuclides 137Cs and 134Cs for all new entered to DB. Quality of reconstructedinformation was analyzed. To group 1, «qualitative¼, it was classified 18,598 notes (53 % of all new entered), measurements in 1986 (including new entered). Dose not exceeding 1 mSv was obtained by 80 % of adults (older than20), as well as 73 % of persons younger than 20. CONCLUSION: To DB of WBC measurements, it was additionally inputted 35,319 notes on results of measurementsdated 1986. New entered information is verified and distributed by the quality groups. Individual exposure dosesevaluated based on those data can be used for further scientific research.


Assuntos
Acidente Nuclear de Chernobyl , Bases de Dados Factuais/estatística & dados numéricos , Bases de Dados Factuais/tendências , Exposição à Radiação/estatística & dados numéricos , Monitoramento de Radiação/estatística & dados numéricos , Radiometria/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Confiabilidade dos Dados , Coleta de Dados/estatística & dados numéricos , Coleta de Dados/tendências , Monitoramento Epidemiológico , Previsões , Humanos , Sistema de Registros , Ucrânia
2.
Artigo em Inglês | MEDLINE | ID: mdl-32037370

RESUMO

Responding to the radiation-related concerns of parents/guardians with infants/small children is an important public health issue for regional recovery after radioactive contamination. This study summarizes the results of a systematic internal contamination screening of infants/small children, aged 0-6 years, using BABYSCAN and individual counselling sessions with physicians about radiation concerns from 2014 to 2018 in Minamisoma City. Of 3,114 participants, no one was found to have internal contamination with radioactive caesium with a detection limit of 50 Bq/body. The questionnaire survey showed a decreasing trend of concerns about food contamination and playing outside as possible causes of internal contamination over time. Because people's concerns were diverse in counselling sessions, individual responses are required. This study showed that examinations using BABYSCAN provide an opportunity for direct dialogue between the parents/guardians of infants/small children and experts. This can be considered a model case for risk communication conducted by the local government after a radioactive contamination incident.


Assuntos
Radioisótopos de Césio/análise , Contagem Corporal Total/estatística & dados numéricos , Criança , Pré-Escolar , Exposição Ambiental/estatística & dados numéricos , Feminino , Contaminação Radioativa de Alimentos/estatística & dados numéricos , Acidente Nuclear de Fukushima , Humanos , Lactente , Recém-Nascido , Japão , Masculino , Centrais Nucleares , Monitoramento de Radiação/estatística & dados numéricos , Liberação Nociva de Radioativos/estatística & dados numéricos , Fatores de Risco , Inquéritos e Questionários
3.
Radiat Prot Dosimetry ; 184(1): 44-53, 2019 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-30371899

RESUMO

Since our previous publication of organ dose for the pediatric CT cohort in the UK, there have been questions about the magnitude of uncertainty in our dose estimates. We therefore quantified shared and unshared uncertainties in empirical CT parameters extracted from 1073 CT films (1978-2008) from 36 hospitals in the study and propagated these uncertainties into organ doses using Monte Carlo random sampling and NCICT organ dose calculator. The average of 500 median brain and marrow doses for the full cohort was 35 (95% confidence interval: 30-40) mGy and 6 (5-7) mGy, respectively. We estimated that shared uncertainty contributed ~99% of coefficient of variation of median brain doses in brain scans compared to unshared uncertainty (1% contribution). We found that the previous brain doses were slightly underestimated for <1990 and overestimated for >1990 compared to the results in the current study due to the revised CTDI models based on CT films.


Assuntos
Algoritmos , Processamento de Imagem Assistida por Computador/métodos , Imagens de Fantasmas , Tomografia Computadorizada por Raios X/métodos , Contagem Corporal Total/estatística & dados numéricos , Adolescente , Adulto , Criança , Pré-Escolar , Estudos de Coortes , Simulação por Computador , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Método de Monte Carlo , Especificidade de Órgãos , Doses de Radiação , Valores de Referência , Incerteza , Reino Unido , Adulto Jovem
4.
Health Phys ; 113(1): 23-29, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28542008

RESUMO

This paper continues a series of publications that analyze the impact of radiation on incidence of circulatory system diseases in the cohort of Russian recovery operation workers (liquidators) and presents the results of the analysis of cardiovascular disease (CVD) incidence. The studied cohort consists of 53,772 liquidators who arrived in the Chernobyl accident zone within the first year after the accident (26 April 1986 to 26 April 1987). The individual doses varied from 0.0001 Gy to 1.42 Gy, and the mean external whole body dose in the cohort was 0.161 Gy. A total of 27,456 cases of CVD were diagnosed during the follow-up period 1986-2012 as a result of annual health examinations. A Poisson regression model was applied to estimate radiation risks and other risk factors associated with CVD. The following factors were identified as risk factors for CVD: the dose, duration of the liquidators' work in the Chernobyl zone, and concomitant diseases (diabetes mellitus, hypertension, overweight, and alcohol dependence). The baseline incidence of CVD is statistically significantly (p < 0.001) associated with all studied concomitant diseases. The incidence of CVD has revealed a statistically significant dose response with the lack of a latent period and with the average ERR Gy = 0.47, 95% CI = 0.31, 0.63, p < 0.001. Radiation risks of CVD statistically significantly (p = 0.01) varied with the duration of liquidators' stay in the Chernobyl zone; for those who stayed in the Chernobyl zone less than 6 wk, ERR/Gy = 0.80, 95% CI = 0.53; 1.08, p < 0.001.


Assuntos
Doenças Cardiovasculares/mortalidade , Acidente Nuclear de Chernobyl , Descontaminação/estatística & dados numéricos , Exposição Ocupacional/estatística & dados numéricos , Exposição à Radiação/estatística & dados numéricos , Lesões por Radiação/mortalidade , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Doses de Radiação , Fatores de Risco , Federação Russa/epidemiologia , Taxa de Sobrevida , Contagem Corporal Total/estatística & dados numéricos , Adulto Jovem
5.
J Nucl Med ; 58(5): 717-722, 2017 05.
Artigo em Inglês | MEDLINE | ID: mdl-27738010

RESUMO

The optimal management of radioactive iodine (RAI) treatment in patients with metastatic thyroid cancer (TC) is still a matter of debate. Methods: We retrospectively analyzed 352 patients with RAI-avid metastatic well-differentiated TC treated with 131I by an empiric fixed activity of 3.7 GBq at Gustave Roussy (GR, n = 231) or by personalized activity (2.7-18.6 GBq) based on whole-body/-blood clearance (WB/BC) dosimetry at Memorial Sloan Kettering Cancer Center (MSKCC, n = 121). The primary endpoint was to compare overall survival (OS) in the 2 groups of patients by log-rank test. Results: Patients received a median cumulative activity of 14.8 GBq at GR and 24.2 GBq at MSKCC (P < 0.0001). The median follow-up after the diagnosis of metastases was 7.2 y (0.4-31 y). Five-year OS was 86.8% and 78.8% for patients treated at GR and at MSKCC, respectively (P < 0.01). However, there was no statistical difference in OS after correction for sex, age at the diagnosis of distant metastases, metastases site, and metastases extension between the 2 centers (P = 0.16). OS at 5 y was 96% and 96% for patients younger than 40 y with micrometastases, 70% and 65% for patients older than 40 y with macrometastases or multiple metastases, and 92% and 87% for younger patients with macrometastases or older patients with micrometastases treated at GR and MSKCC, respectively (P = not significant). Conclusion: Routine use of WB/BC dosimetry without lesional dosimetry provided no OS advantage when compared with empiric fixed RAI activity in the management of thyroid cancer patients with RAI-avid distant metastases.


Assuntos
Radioisótopos do Iodo/uso terapêutico , Exposição à Radiação/estatística & dados numéricos , Radioterapia Conformacional/mortalidade , Neoplasias da Glândula Tireoide/mortalidade , Neoplasias da Glândula Tireoide/radioterapia , Contagem Corporal Total/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Relação Dose-Resposta à Radiação , França/epidemiologia , Humanos , Masculino , Taxa de Depuração Metabólica , Pessoa de Meia-Idade , Metástase Neoplásica , Prevalência , Compostos Radiofarmacêuticos/uso terapêutico , Dosagem Radioterapêutica , Estudos Retrospectivos , Fatores de Risco , Taxa de Sobrevida , Resultado do Tratamento , Contagem Corporal Total/métodos , Adulto Jovem
6.
Health Phys ; 111(5): 451-64, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27682904

RESUMO

The Tokyo Electric Power Company's Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident in 2011 resulted in a release of radionuclides into the environment (I: 142.9 PBq, Cs:12.4 PBq). This study presents the results of internal doses to 174 residents living near the FDNPP at the time of the accident based on whole-body (WB) measurements performed by the National Institute of Radiological Sciences (NIRS) during the period between 27 June and 28 July 2011. The 174 subjects consisted of 125 adults (≥18-y) and 49 children (<18-y) and included 90 persons of Namie town, one of the municipalities heavily contaminated with the radionuclides. The number of subjects with significant detection of both Cs and Cs was relatively small: 28.8% for the adults and 4.1% for the children. A significant gender difference in the Cs detection rate (males > females) was observed in the adults but not the children. In this study, the committed effective dose (CED) from Cs and Cs was calculated based on individual WB contents (Cs) corrected against body size, the observed body content ratio of Cs to Cs, and the assumed intake scenario (namely, acute inhalation of Type F compounds on 12 March 2011 when the first explosive event occurred at the site of the FDNPP). The 90th-percentile CED value for the adults was around 0.1 mSv and the maximum CED (0.63 mSv) was found in an elderly male. Comparable CED results were obtained in other WB measurements subsequently performed by the Japan Atomic Energy Agency (JAEA) in a similar manner to that of the NIRS, suggesting that the contribution of ingestion to the WB content observed would be trivial for most of the JAEA subjects. The intake ratio of I to Cs was evaluated to be 3~5 based on the I thyroid measurement data of Tokonami et al. Using the average intake ratio of 3.8, the resulting median and maximum thyroid-equivalent doses to the adult subjects of this study were estimated at 3.5 mSv and 84 mSv, respectively.


Assuntos
Radioisótopos de Césio/análise , Acidente Nuclear de Fukushima , Centrais Nucleares/estatística & dados numéricos , Exposição à Radiação/estatística & dados numéricos , Cinza Radioativa/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Exposição à Radiação/análise , Cinza Radioativa/análise , Distribuição por Sexo , Contagem Corporal Total/métodos , Adulto Jovem
7.
Appl Radiat Isot ; 117: 36-41, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27094250

RESUMO

The objectives of this study were to measure the entrance surface air kerma (ESAK) and the effective doses in pediatric patients undergoing micturating cystourethrography (MCU) procedures. The ESAK was determined using calibrated thermoluminescent dosimeters (TLD- GR 200 A) in 167 pediatric patients. The patient population was categorized into three groups according to age (0-5 years (group 1), 6-10 years (group 2) and 11-15 years (group 3)). The mean ESAK±SD and range (mGy) resulting from a MCU procedure was estimated to be 2.2±0.5 (0.8-9.2), 2.48±0.6 (0.9-8.1) and 3.90±0.6 (1.1-10.3) for group 1, 2 and 3, respectively. The mean effective dose was between 0.03 and 0.4 mSv per procedure for the pediatric population. Pediatric patients were exposed to avoidable radiation doses because no gonad shields were used.


Assuntos
Cistografia/estatística & dados numéricos , Exposição à Radiação/análise , Exposição à Radiação/estatística & dados numéricos , Monitoramento de Radiação/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Adolescente , Distribuição por Idade , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Sudão/epidemiologia , Micção
8.
Int J Radiat Biol ; 92(2): 59-70, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26857121

RESUMO

PURPOSE: An interlaboratory comparison of radiation dosimetry was conducted to determine the accuracy of doses being used experimentally for animal exposures within a large multi-institutional research project. The background and approach to this effort are described and discussed in terms of basic findings, problems and solutions. METHODS: Dosimetry tests were carried out utilizing optically stimulated luminescence (OSL) dosimeters embedded midline into mouse carcasses and thermal luminescence dosimeters (TLD) embedded midline into acrylic phantoms. RESULTS: The effort demonstrated that the majority (4/7) of the laboratories was able to deliver sufficiently accurate exposures having maximum dosing errors of ≤5%. Comparable rates of 'dosimetric compliance' were noted between OSL- and TLD-based tests. Data analysis showed a highly linear relationship between 'measured' and 'target' doses, with errors falling largely between 0 and 20%. Outliers were most notable for OSL-based tests, while multiple tests by 'non-compliant' laboratories using orthovoltage X-rays contributed heavily to the wide variation in dosing errors. CONCLUSIONS: For the dosimetrically non-compliant laboratories, the relatively high rates of dosing errors were problematic, potentially compromising the quality of ongoing radiobiological research. This dosimetry effort proved to be instructive in establishing rigorous reviews of basic dosimetry protocols ensuring that dosing errors were minimized.


Assuntos
Laboratórios/estatística & dados numéricos , Exposição à Radiação/análise , Contagem Corporal Total/instrumentação , Irradiação Corporal Total/instrumentação , Absorção de Radiação , Animais , Desenho de Equipamento , Análise de Falha de Equipamento , Camundongos , Exposição à Radiação/estatística & dados numéricos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Contagem Corporal Total/métodos , Contagem Corporal Total/estatística & dados numéricos , Irradiação Corporal Total/estatística & dados numéricos
9.
J Nucl Med ; 57(2): 238-41, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26564326

RESUMO

UNLABELLED: The role of CT in PET/CT imaging includes acquisition techniques for diagnostic, anatomic localization, and attenuation correction purposes. Diagnostic reference levels of the volumetric CT dose index (CTDIvol) are available for dedicated CT procedures on selected body regions, but similar reference levels for whole-body CT used in PET/CT examinations are limited. This work reports CTDIvol values from sites that conduct whole-body oncologic PET/CT examinations and participated in the scanner validation program of the Society of Nuclear Medicine and Molecular Imaging Clinical Trials Network. METHODS: From 2010 to 2014, a total of 154 sites submitted CT acquisition parameters used in their clinical (18)F-FDG PET/CT oncology protocols. From these parameters, the CTDIvol was estimated using the ImPACT CTDI dosimetry tables. Histograms of CTDIvol values were created for each year, and descriptive statistics, including mean, median, and 75th percentile, were reported. Repeated-measures ANOVA was performed to determine whether significant differences occurred between reporting years. RESULTS: A wide range of technical parameters was reported, most notably in tube current. Between 2010 and 2014, the median CTDIvol ranged from 4.9 to 6.2 mGy and the 75th percentile from 9.7 to 10.2 mGy. There was no significant change in CTDIvol between reporting years (repeated-measures ANOVA, P = 0.985). CONCLUSION: The 75th percentile CTDIvol reported in this work was 9.8 mGy averaged over all reporting years. These data provide a resource for establishing CTDIvol reference values specific to performing CT in PET/CT whole-body examinations. The wide ranges of CT acquisition parameters reported by sites suggest that CTDIvol reference levels may be beneficial for optimization of CT protocols.


Assuntos
Tomografia por Emissão de Pósitrons/estatística & dados numéricos , Doses de Radiação , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Fluordesoxiglucose F18 , Humanos , Radiometria , Compostos Radiofarmacêuticos , Padrões de Referência , Valores de Referência , Reprodutibilidade dos Testes
10.
Disaster Med Public Health Prep ; 10(1): 34-7, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26349438

RESUMO

OBJECTIVE: Although much attention is now being paid to the health risks associated with nuclear disasters, reliable information is lacking. We retrospectively evaluated the health effects of living in highly contaminated radioactive areas in Japan. METHODS: The health evaluation was conducted in Tamano district, Fukushima prefecture, in 2011 and 2012. The surface deposition density of cesium in Tamano was 600 to 1000 kBq/m2 shortly after the Fukushima nuclear accident. Clinical parameters included body mass index, blood pressure, and laboratory examinations for blood cell counts, glucose levels, and lipid profiles. A screening program for internal and external exposure was also implemented. RESULTS: One hundred fifty-five residents participated in the health evaluation. Significant decreases in average body mass index and blood pressure were observed from 2011 to 2012. Annual internal exposure levels did not exceeded 1 mSv in any participants. The levels of external exposure ranged from 1.3 to 4.3 mSv/y measured in the first test period but decreased to 0.8 to 3.6 mSv/y in the second test period. CONCLUSIONS: These findings suggest that inhabiting nuclear contaminated areas is not always associated with short-term health deterioration and that radiation exposure can be controlled within safety limitations.


Assuntos
Promoção da Saúde/métodos , Monitoramento de Radiação/métodos , Adolescente , Adulto , Idoso , Feminino , Acidente Nuclear de Fukushima , Promoção da Saúde/estatística & dados numéricos , Humanos , Japão , Masculino , Pessoa de Meia-Idade , Avaliação de Resultados em Cuidados de Saúde/estatística & dados numéricos , Exposição à Radiação/estatística & dados numéricos , Lesões por Radiação/epidemiologia , Monitoramento de Radiação/estatística & dados numéricos , Estudos Retrospectivos , Fatores de Risco , Contagem Corporal Total/mortalidade , Contagem Corporal Total/estatística & dados numéricos
11.
J Am Coll Radiol ; 12(8): 815-23, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26250975

RESUMO

As CT use steadily rises, concern over potential risks of radiation exposure from medical imaging has received increasing attention. Since May 2011, the ACR Dose Index Registry (DIR) has been open for general participation and has been collecting CT radiation dose data from an increasing number of facilities of various types. In this introductory review, we analyze the first three years of ACR DIR data, categorize the 10 most commonly performed CT examinations nationwide, review the variability of the recorded radiation dose indices for each, and take preliminary steps toward identifying possible factors associated with variability in dose indices. We believe that disseminating such information will help prompt informed improvements in standardization of CT protocols with respect to radiation dose.


Assuntos
Absorção de Radiação , Exposição à Radiação/estatística & dados numéricos , Proteção Radiológica/estatística & dados numéricos , Sistema de Registros , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Adulto , Feminino , Humanos , Masculino , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Estados Unidos/epidemiologia
12.
Phys Med Biol ; 60(14): 5601-25, 2015 Jul 21.
Artigo em Inglês | MEDLINE | ID: mdl-26134511

RESUMO

This paper describes the development and testing of VirtualDose--a software for reporting organ doses for adult and pediatric patients who undergo x-ray computed tomography (CT) examinations. The software is based on a comprehensive database of organ doses derived from Monte Carlo (MC) simulations involving a library of 25 anatomically realistic phantoms that represent patients of different ages, body sizes, body masses, and pregnant stages. Models of GE Lightspeed Pro 16 and Siemens SOMATOM Sensation 16 scanners were carefully validated for use in MC dose calculations. The software framework is designed with the 'software as a service (SaaS)' delivery concept under which multiple clients can access the web-based interface simultaneously from any computer without having to install software locally. The RESTful web service API also allows a third-party picture archiving and communication system software package to seamlessly integrate with VirtualDose's functions. Software testing showed that VirtualDose was compatible with numerous operating systems including Windows, Linux, Apple OS X, and mobile and portable devices. The organ doses from VirtualDose were compared against those reported by CT-Expo and ImPACT-two dosimetry tools that were based on the stylized pediatric and adult patient models that were known to be anatomically simple. The organ doses reported by VirtualDose differed from those reported by CT-Expo and ImPACT by as much as 300% in some of the patient models. These results confirm the conclusion from past studies that differences in anatomical realism offered by stylized and voxel phantoms have caused significant discrepancies in CT dose estimations.


Assuntos
Simulação por Computador , Imagens de Fantasmas , Software , Tomografia Computadorizada por Raios X/métodos , Contagem Corporal Total/estatística & dados numéricos , Adolescente , Adulto , Tamanho Corporal , Criança , Pré-Escolar , Bases de Dados Factuais , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Modelos Teóricos , Método de Monte Carlo , Obesidade , Especificidade de Órgãos , Gravidez , Doses de Radiação , Radiometria/métodos
13.
Pediatr Radiol ; 45(9): 1282-92, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25801905

RESUMO

BACKGROUND: It is necessary to develop a mechanism to estimate and analyze cumulative radiation risks from multiple CT exams in various clinical scenarios in children. OBJECTIVE: To identify major contributors to high cumulative CT dose estimates using actual dose-length product values collected for 5 years in children. MATERIALS AND METHODS: Between August 2006 and July 2011 we reviewed 26,937 CT exams in 13,803 children. Among them, we included 931 children (median age 3.5 years, age range 0 days-15 years; M:F = 533:398) who had 5,339 CT exams. Each child underwent at least three CT scans and had accessible radiation dose reports. Dose-length product values were automatically extracted from DICOM files and we used recently updated conversion factors for age, gender, anatomical region and tube voltage to estimate CT radiation dose. We tracked the calculated CT dose estimates to obtain a 5-year cumulative value for each child. The study population was divided into three groups according to the cumulative CT dose estimates: high, ≥30 mSv; moderate, 10-30 mSv; and low, <10 mSv. We reviewed clinical data and CT protocols to identify major contributors to high and moderate cumulative CT dose estimates. RESULTS: Median cumulative CT dose estimate was 5.4 mSv (range 0.5-71.1 mSv), and median number of CT scans was 4 (range 3-36). High cumulative CT dose estimates were most common in children with malignant tumors (57.9%, 11/19). High frequency of CT scans was attributed to high cumulative CT dose estimates in children with ventriculoperitoneal shunt (35 in 1 child) and malignant tumors (range 18-49). Moreover, high-dose CT protocols, such as multiphase abdomen CT (median 4.7 mSv) contributed to high cumulative CT dose estimates even in children with a low number of CT scans. CONCLUSION: Disease group, number of CT scans, and high-dose CT protocols are major contributors to higher cumulative CT dose estimates in children.


Assuntos
Absorção de Radiação , Doses de Radiação , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Adolescente , Distribuição por Idade , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Estudos Longitudinais , Masculino , Especificidade de Órgãos , República da Coreia/epidemiologia , Medição de Risco , Distribuição por Sexo
14.
J Radiol Prot ; 35(1): 197-207, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25647828

RESUMO

Positron emission tomography (PET) is now one of the most important methods in the diagnosis of cancer diseases. Due to the rapid growth of PET/CT centres in Poland in less than a decade, radiation protection and, consequently, the assessment of worker exposure to ionising radiation, emitted mainly by the isotope (18)F, have become essential issues. The main aim of the study was to analyse the doses received by workers employed in the Medical Diagnostic Centre. The analysis comprises a physicist, three nurses, three physicians, three technicians, as well as two administrative staff employees. High-sensitivity thermoluminescent detectors (TLDs) were used to measure the doses for medical staff. The personnel was classified into categories, among them employees having direct contact with the 'source of radiation'-(18)FDG. The TLDs were placed on the fingertips of both hands and they were also attached at the level of eye lenses, thyroid and gonads depending on the assigned category. The highest dose of radiation was observed during the administration of the (18)FDG to the patients. In the case of the physicist, the highest dose was recorded during preparation of the radiopharmaceutical-(18)FDG. The body parts most exposed to ionizing radiation are the fingertips of the thumb, index and middle finger.


Assuntos
Fluordesoxiglucose F18/análise , Pessoal de Saúde/estatística & dados numéricos , Exposição Ocupacional/estatística & dados numéricos , Tomografia por Emissão de Pósitrons/estatística & dados numéricos , Doses de Radiação , Dosimetria Termoluminescente/estatística & dados numéricos , Humanos , Imagem Multimodal/estatística & dados numéricos , Polônia/epidemiologia , Compostos Radiofarmacêuticos/análise , Reprodutibilidade dos Testes , Medição de Risco , Sensibilidade e Especificidade , Dosimetria Termoluminescente/instrumentação , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos
15.
Health Phys ; 108(1): 67-75, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25437522

RESUMO

Radioactive material deposited in multiple organs of the body is likely to confound a result of an in vivo measurement performed over the lungs, the most frequently monitored organ for occupational exposure. The significance of this interference was evaluated by measuring anthropometric torso phantoms containing lungs, liver, skeleton, and axillary lymph nodes, each with a precisely known quantity of 241Am uniformly distributed in the organs. Arrays of multiple high-resolution germanium detectors were positioned over organs within the torso phantom containing 241Am or over proximal organs without activity to determine the degree of measurement confounding due to photons emitted from other source organs. A set of four mathematical response functions describes the measured count rate with detectors positioned over each of the relevant organs and 241Am contained in the measured organ or one of the other organs selected as a confounder. Simultaneous solution of these equations by matrix algebra, where the diagonal terms of the matrix are calibration factors for a direct measurement of activity in an organ and the off-diagonal terms reflect the contribution (i.e., interference or cross-talk) produced by 241Am in a confounding organ, yields the activity deposited in each of the relevant organs. The matrix solution described in this paper represents a method for adjusting a result of 241Am measured directly in one organ for interferences that may arise from 241Am deposited elsewhere and represents a technically valid procedure to aid in evaluating internal dose based upon in vivo measurements for those radioactive materials known to deposit in multiple organs.


Assuntos
Amerício/análise , Pulmão/efeitos da radiação , Contagem Corporal Total/métodos , Amerício/efeitos adversos , Osso e Ossos/química , Osso e Ossos/efeitos da radiação , Humanos , Fígado/química , Fígado/efeitos da radiação , Pulmão/química , Linfonodos/química , Linfonodos/efeitos da radiação , Exposição Ocupacional/estatística & dados numéricos , Especificidade de Órgãos , Imagens de Fantasmas , Monitoramento de Radiação/métodos , Monitoramento de Radiação/estatística & dados numéricos , Liberação Nociva de Radioativos , Crânio/química , Crânio/efeitos da radiação , Contagem Corporal Total/estatística & dados numéricos
16.
AJR Am J Roentgenol ; 204(1): W27-36, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25539270

RESUMO

OBJECTIVE. The purpose of this study was to comprehensively study estimated radiation doses for subjects included in the main analysis of the Combined Non-invasive Coronary Angiography and Myocardial Perfusion Imaging Using 320 Detector Computed Tomography (CORE320) study ( ClinicalTrials.gov identifier NCT00934037), a clinical trial comparing combined CT angiography (CTA) and perfusion CT with the reference standard catheter angiography plus myocardial perfusion SPECT. SUBJECTS AND METHODS. Prospectively acquired data on 381 CORE320 subjects were analyzed in four groups of testing related to radiation exposure. Radiation dose estimates were compared between modalities for combined CTA and perfusion CT with respect to covariates known to influence radiation exposure and for the main clinical outcomes defined by the trial. The final analysis assessed variations in radiation dose with respect to several factors inherent to the trial. RESULTS. The mean radiation dose estimate for the combined CTA and perfusion CT protocol (8.63 mSv) was significantly (p < 0.0001 for both) less than the average dose delivered from SPECT (10.48 mSv) and the average dose from diagnostic catheter angiography (11.63 mSv). There was no significant difference in estimated CTA-perfusion CT radiation dose for subjects who had false-positive or false-negative results in the CORE320 main analyses in a comparison with subjects for whom the CTA-perfusion CT findings were in accordance with the reference standard SPECT plus catheter angiographic findings. CONCLUSION. Radiation dose estimates from CORE320 support clinical implementation of a combined CT protocol for assessing coronary anatomy and myocardial perfusion.


Assuntos
Absorção de Radiação , Angiografia Coronária/estatística & dados numéricos , Estenose Coronária/diagnóstico por imagem , Doses de Radiação , Tomografia Computadorizada de Emissão de Fóton Único/estatística & dados numéricos , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Idoso , Feminino , Humanos , Internacionalidade , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
17.
Radiat Prot Dosimetry ; 163(2): 181-7, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24795393

RESUMO

More and more anaesthetists are getting involved in interventional radiology procedures and so it is important to know the radiation dose and to optimise protection for anaesthetists. In this study, based on Monte Carlo simulations and field measurements, both the whole-body doses and eye lens dose of anaesthetists were studied. The results showed that the radiation exposure to anaesthetists not only depends on their workload, but also largely varies with their standing positions and beam projections during interventional procedures. The simulation results showed that the effective dose to anaesthetists may vary with their standing positions and beam projections to more than a factor of 10, and the eye lens dose may vary with the standing positions and beam projections to more than a factor of 200. In general, a close position to the bed and the left lateral (LLAT) beam projection will bring a high exposure to anaesthetists. Good correlations between the eye lens dose and the doses at the neck, chest and waist over the apron were observed from the field measurements. The results indicate that adequate arrangements of anaesthesia device or other monitoring equipment in the fluoroscopy rooms are useful measures to reduce the radiation exposure to anaesthetists, and anaesthetists should be aware that they will receive the highest doses under left lateral beam projection.


Assuntos
Anestesiologia/estatística & dados numéricos , Cristalino , Exposição Ocupacional/estatística & dados numéricos , Postura , Radiografia Intervencionista/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Absorção de Radiação , Simulação por Computador , Humanos , Modelos Estatísticos , Método de Monte Carlo , Exposição Ocupacional/prevenção & controle , Proteção Radiológica/estatística & dados numéricos , Medição de Risco/métodos , Contagem Corporal Total/métodos , Carga de Trabalho/estatística & dados numéricos , Raios X
18.
Radiat Prot Dosimetry ; 163(3): 319-24, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24891405

RESUMO

The purpose of this study is to present a national survey that was performed in Greece for the establishment of national Dose Reference Levels (DRLs) for seven common adult Computed Tomography (CT) examinations. Volumetric computed tomography dose index and dose-length product values were collected from the post-data page of 65 'modern' systems that incorporate tube current modulation. Moreover, phantom dose measurements on 26 'older' systems were performed. Finally, the effective dose to the patient from a typical acquisition during these examinations was estimated. The suggested national DRLs are generally comparable with respective published values from similar European studies, with the exception of sinuses CT, which presents significantly higher values. This fact, along with the large variation of the systems' dose values that were observed even for scanners of the same type, indicates a need for further patient protection optimisation without compromising the clinical outcome.


Assuntos
Tomografia Computadorizada de Feixe Cônico/estatística & dados numéricos , Tomografia Computadorizada de Feixe Cônico/normas , Exposição Ambiental/análise , Exposição Ambiental/normas , Contagem Corporal Total/estatística & dados numéricos , Contagem Corporal Total/normas , Adulto , Carga Corporal (Radioterapia) , Tomografia Computadorizada de Feixe Cônico/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento/normas , Grécia , Guias como Assunto , Humanos , Masculino , Imagens de Fantasmas/normas , Doses de Radiação , Proteção Radiológica/normas , Proteção Radiológica/estatística & dados numéricos , Valores de Referência
19.
Radiat Prot Dosimetry ; 163(3): 353-61, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24982262

RESUMO

In order to effectively and appropriately manage external radiation doses in the affected areas of Fukushima, it is important to identify when, where and how much exposure occurred. It is also necessary to quantitatively measure external exposure and air dose rates for different activity patterns in individuals living and working in Japanese-style buildings. The authors used a new personal dosemeter (D-shuttle) along with a global positioning system and geographical information system to relate personal dose rate with activity patterns and air dose rate. Hourly individual doses obtained by D-shuttle can provide an effective communication tool for those who want to identify when and how much exposure occurs. Personal monitoring of 26 volunteers showed that personal doses obtained from D-shuttle were ∼30% of cumulative air dose estimated by data from the airborne monitoring survey. This analysis showed that, for most study volunteers, the exposure from staying at home represented about half of the total cumulative dose. This suggests that even though the peak exposure doses may be observed outside of working hours, to develop appropriate countermeasures for external dose reduction, it is thus important to identify the contributions of individuals' time-activities. This study provides a valuable basis for developing a realistic and pragmatic method to estimate external doses of individuals in Fukushima.


Assuntos
Poluição do Ar em Ambientes Fechados/estatística & dados numéricos , Contaminação Radioativa do Ar/estatística & dados numéricos , Carga Corporal (Radioterapia) , Acidente Nuclear de Fukushima , Habitação/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Poluentes Radioativos do Ar/análise , Poluição do Ar em Ambientes Fechados/análise , Contaminação Radioativa do Ar/análise , Humanos , Japão , Doses de Radiação
20.
J Am Coll Radiol ; 12(1): 82-9, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25086959

RESUMO

PURPOSE: The purpose of this prospective study was to investigate absolute radiation exposure values and factors that influence radiation exposure of interventionists during CT-guided interventions (CTGIs). To our knowledge, no data exist regarding the radiation dose to which the interventionist is exposed during these procedures. METHODS: Absolute radiation dose values from a total of 131 CTGIs were analyzed. Radiation dose values were collected by thermoluminescent dosimeters that were positioned above the lead protection being worn, on the forehead, thyroid, chest, gonads, and right and left hand and foot. The radiation doses were analyzed with respect to the experience level of the person performing the procedure, the degree of difficulty measured on a 4-point Likert scale, the lesion size measured on a 3-point Likert scale, and the CT system used. RESULTS: Median whole-body dose was 12 µSv. With the exception of the forehead, all whole-body radiation doses were statistically significantly lower in CTGIs performed using the modern dual-source CT system compared with the 16-slice multi-detector CT. For CTGIs rated as more complex, the radiation exposure of the radiologist performing the procedure was statistically significantly higher, with the exception of the left hand. A statistically significantly lower median whole-body dose was measured for inexperienced compared with experienced radiologists. However, a few dose measurements of more than 1 mSv were found at the right hand. CONCLUSIONS: Radiation exposure measured during CTGIs is low (<50 µSv). Because the radiation dose was higher in more-complex interventions and for 16-slice multi-detector row CT, inexperienced radiologists should focus on less-complex procedures.


Assuntos
Corpo Clínico Hospitalar/estatística & dados numéricos , Exposição Ocupacional/estatística & dados numéricos , Doses de Radiação , Radiografia Intervencionista/estatística & dados numéricos , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Contagem Corporal Total/estatística & dados numéricos , Idoso , Feminino , Alemanha , Humanos , Masculino , Exposição Ocupacional/análise , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Cirurgia Assistida por Computador/estatística & dados numéricos
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