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1.
Obes Surg ; 33(12): 3951-3961, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37864735

RESUMO

PURPOSE: The literature on long-term outcomes of duodenal switch (DS) compared to single anastomosis duodenal switch (SADI-S) procedures is lacking. We evaluated the long-term outcomes of SADI-S compared to those after the classic DS procedure. METHODS: This is a follow-up report from a single-institution prospective cohort study comparing long-term outcomes of SADI-S versus DS both as one- and two-stage procedures (ClinicalTrials.gov: NCT02792166). Data is depicted as count (percentage) or median (interquartile range). RESULTS: Forty-two patients underwent SADI-S, of whom 11 had it as a second-stage procedure (26%). Of 20 patients who underwent DS, twelve had it as a second-stage procedure (60%). Both groups were similar at baseline. Median follow-up times for one-stage SADI-S and DS were 57 (24) and 57 (9) months, respectively (p = 0.93). Similar BMI reductions were observed after one-stage SADI-S (16.5 kg/m2 [8.5]) and DS (18.9 kg/m2 [7.2]; p = 0.42). At median follow-up of 51 (21) and 60 (15) months after second-stage SADI-S and DS, respectively (p = 0.60), surgical procedures yielded reductions in BMI of 20.5 kg/m2 (14.0) and 24.0 kg/m2 (13.9), respectively (p = 0.52). Follow-up rates were similar for one-stage (≥ 88%; p = 0.29) and second-stage procedures (≥ 83%; p = 0.16). Similar diabetes and hypertension remissions were found (p = 0.77; P = 0.54, respectively). Despite fat-soluble vitamin deficiencies at baseline, after supplementation, they were either eliminated or less prevalent long-term after SADI-S. Daily bowel movements were also less frequent. CONCLUSIONS: Long-term weight and comorbidity outcomes after SADI-S are similar to those of DS both as one- and two-stage surgeries. SADI-S procedure may allow for similar beneficial outcomes with less burden from gastrointestinal symptoms and fat-soluble vitamin deficiencies.


Assuntos
Deficiência de Vitaminas , Desvio Biliopancreático , Derivação Gástrica , Obesidade Mórbida , Humanos , Obesidade Mórbida/cirurgia , Estudos Prospectivos , Estudos de Coortes , Desvio Biliopancreático/métodos , Gastrectomia/métodos , Anastomose Cirúrgica , Deficiência de Vitaminas/cirurgia , Estudos Retrospectivos , Derivação Gástrica/métodos , Duodeno/cirurgia
2.
Obes Surg ; 30(2): 427-438, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31749110

RESUMO

BACKGROUND: Vitamin and mineral deficiencies are common after a sleeve gastrectomy (SG). The aim of this study is to examine the effectiveness of a specialized bariatric multivitamin (WLS Optimum) for SG patients on deficiencies compared with a regular multivitamin (MVS) for up to 5 years. METHODS: Data of all patients who underwent a SG procedure in the Catharina Hospital Eindhoven (CZE) between July 2011 and July 2016 were collected and retrospectively analyzed. All patients who completed a preoperative blood test and at least one blood withdrawal during the first operative year were included in this study. RESULTS: This study included 970 patients; 291 patients in the WLS-user group and 679 patients in the non-WLS-user group. In favor of the user group, significantly less de novo deficiencies were found of vitamin B1 (2 years) and vitamin B6 (two and three), folic acid (1 and 2 years), and vitamin B12 (at 1 year). Binomial logistic regression showed a significant influence of multivitamin supplementation mainly on ferritin; vitamins B1, B6, B12, and D; and folic acid, (all p < 0.05). The total number of de novo deficiencies was significantly reduced during the whole study for all WLS Optimum users. CONCLUSIONS: Vitamin deficiencies are common, and postoperative nutritional management after SG is underestimated. The use of a specialized multivitamin supplement resulted in higher mean serum concentrations and less deficiencies of vitamin B1, folic acid, and vitamin B12. This study shows that SG patients benefit from the specialized multivitamin supplements, but adjustments are required for iron and vitamin B6 content.


Assuntos
Deficiência de Vitaminas/prevenção & controle , Suplementos Nutricionais , Gastrectomia/efeitos adversos , Obesidade Mórbida/tratamento farmacológico , Obesidade Mórbida/cirurgia , Vitaminas/administração & dosagem , Adulto , Deficiência de Vitaminas/epidemiologia , Deficiência de Vitaminas/etiologia , Deficiência de Vitaminas/cirurgia , Composição de Medicamentos , Feminino , Seguimentos , Gastrectomia/métodos , Humanos , Síndromes de Malabsorção/tratamento farmacológico , Síndromes de Malabsorção/epidemiologia , Síndromes de Malabsorção/etiologia , Masculino , Pessoa de Meia-Idade , Países Baixos/epidemiologia , Obesidade Mórbida/epidemiologia , Complicações Pós-Operatórias/tratamento farmacológico , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Vitaminas/química
3.
Obes Surg ; 29(12): 4142-4143, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31468304

RESUMO

Roux-en-Y gastric bypass (RYGB) is recently the second most frequent operation worldwide and is only preceded by sleeve gastrectomy. We present an alternative technique of reversal of RYGB. There is no need to dissect or resect the gastrojejunal anastomosis. This dissection might be difficult as the gastrojejunal anastomosis might be adherent to the residual stomach. The 2 anastomoses performed are technically easy and done on healthy non-inflammatory tissue.


Assuntos
Anastomose Cirúrgica/métodos , Derivação Gástrica/efeitos adversos , Reoperação/métodos , Adulto , Deficiência de Vitaminas/etiologia , Deficiência de Vitaminas/cirurgia , Feminino , Humanos , Desnutrição/etiologia , Desnutrição/cirurgia , Duração da Cirurgia
4.
Obes Surg ; 27(12): 3327-3329, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28965167

RESUMO

BACKGROUND: Despite the success of the Biliopancreatic Diversion with Duodenal Switch procedure (BPD-DS) in weight loss and comorbidities resolution, reversal of BPD-DS is necessary in 0.2-0.6% of BPD-DS cases for vitamin, protein, and other micronutrient deficiencies. Different techniques are available to reverse the malabsorptive component of the BPD-DS. METHODS: A retrospective chart review for a 37-year-old female patient who presented with lower leg edema and signs of malnutrition 5 years after a BPD/DS. The patient was not compliant with the required daily vitamin and protein intake. Thus, after extensive discussion with the patient, a decision was made to reverse the malabsorptive component of the BPD-DS. RESULTS: A laparoscopic reversal of the malabsorptive component of the BPD-DS was concluded by transecting the roux limb distally at the ileo-ileal anastomosis and reconnecting it to the proximal jejunum thus substantially lengthening the common channel for absorption. At 6 months follow-up, the patient normalized her vitamin deficiency and had a normal level of serum protein. Her weight, BMI, EWL%, and TBWL% were 72 kg, 27.5 kg/m2, 90%, and 45%, respectively. CONCLUSIONS: Proper nutrition and vitamin supplementation is essential to avoid nutritional complications. Different techniques are available to reverse the malabsorptive component of the BPD-DS. However, no standard approach is adopted by the surgical community. We demonstrate our preferred technique in reversing the malabsorptive component of the BPD-DS.


Assuntos
Desvio Biliopancreático/efeitos adversos , Duodeno/cirurgia , Desnutrição/cirurgia , Obesidade Mórbida/cirurgia , Complicações Pós-Operatórias/cirurgia , Reoperação/métodos , Adulto , Anastomose Cirúrgica , Deficiência de Vitaminas/etiologia , Deficiência de Vitaminas/cirurgia , Desvio Biliopancreático/métodos , Duodeno/patologia , Edema/etiologia , Edema/cirurgia , Feminino , Humanos , Laparoscopia/métodos , Desnutrição/etiologia , Estudos Retrospectivos
5.
Zentralbl Chir ; 134(3): 214-24; discussion 225, 2009 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-19536714

RESUMO

BACKGROUND: Obesity is increasing worldwide at an alarming rate. Particularly in Western countries, obesity and related problems have become a serious medical problem and an enormous socio-economic burden. DISCUSSION: Currently, surgery is the only avail-able treatment for patients with severe obesity which leads to sustained weight loss and cure of co-morbidities in the majority of the patients. The increase in the number of bariatric operations and the occasional failure and complications of these surgical procedures have resulted in an increased need for revision surgery. Overall, 10-25 % of patients are expected to need a revision for failure of the primary bariatric procedure. The main indications for revision procedures are inadequate weight loss, surgery-related complications as well as surgical emergencies and long-term complications caused by malnutrition or -vitamin deficiencies. Unfortunately, there are currently no randomised trials to answer the question as to which operation should be performed in which patient and after which procedure. Decisions are often influenced by the expertise and preference of the operating surgeon as well as by patient's preference. Thus, a systematic review of published data to this complex issue appears to be helpful and important for daily surgical practise. CONCLUSIONS: Revision bariatric procedures are technically more complex and associated with increased postoperative complications. These operations should basically be performed in centres with profound expertise in this field of surgery, and - whenever possible - laparoscopically. However, every abdominal surgeon should be able to diagnose and treat some acute complications. After failed restrictive procedures, revision is recommended only in cases of complications but with adequate weight loss at the time of failure. Otherwise, conversion to combined procedures should be considered. After the failure of combined procedures, further weight loss or successful treatment of complications can be achieved by adding more restriction and/or malabsorption components. The latter is associated with an increased risk of nutritional sequelae.


Assuntos
Cirurgia Bariátrica/métodos , Complicações Pós-Operatórias/cirurgia , Deficiência de Vitaminas/etiologia , Deficiência de Vitaminas/cirurgia , Migração de Corpo Estranho/etiologia , Migração de Corpo Estranho/cirurgia , Gastroplastia/instrumentação , Humanos , Laparoscopia , Síndromes de Malabsorção/etiologia , Síndromes de Malabsorção/cirurgia , Satisfação do Paciente , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/etiologia , Desnutrição Proteico-Calórica/etiologia , Desnutrição Proteico-Calórica/cirurgia , Reoperação , Fatores de Risco , Falha de Tratamento , Redução de Peso
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