1.
J Med Chem
; 20(8): 1065-8, 1977 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-894676
RESUMO
Two minor metabolites of (+)-propoxyphene were prepared in both the (+/-) and (+) forms. The optically pure forms were synthesized by a degradative route from (+)-propoxyphene. The di-N-demethylated metabolite 10a,b had weak analgesic activity while the cyclized oxazine metabolite 7a was inactive.
Assuntos
Dextropropoxifeno/análogos & derivados , Analgésicos/síntese química , Animais , Dextropropoxifeno/síntese química , Dextropropoxifeno/metabolismo , Camundongos , Estereoisomerismo
2.
Yakugaku Zasshi
; 92(4): 421-30, 1972 Apr.
Artigo
em Japonês
| MEDLINE
| ID: mdl-5065438
3.
Farmaco Sci
; 24(10): 900-4, 1969 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5361905
