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1.
Am J Otolaryngol ; 44(2): 103750, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36630732

RESUMO

Empty nose syndrome (ENS) is a relatively rare disease found in patients who have undergone sinonasal surgery, characterized by excessive reduction of the turbinate, causing intranasal turbulence and loss of receptors within the nasal mucosa. Patients diagnosed with the disease usually experience symptoms including dryness of the nose, nasal pain, paradoxical nasal obstruction, and crusts in the nasal cavity. ENS can be treated with conservative care such as nasal irrigation or nasal moisturizers. Accurate efficacy of surgical treatment of ENS is often difficult to predict and is accompanied by operational obstacles and complications. Platelet-rich plasma (PRP) has recently gained attention as a regenerative therapy in several medical fields. We present two cases of ENS treated by injection of PRP as a simple and less invasive method, and describe its efficacy with nasal endoscopy and subjective questionnaires.


Assuntos
Doenças Nasais , Plasma Rico em Plaquetas , Complicações Pós-Operatórias , Humanos , Mucosa Nasal/cirurgia , Nariz/cirurgia , Doenças Nasais/terapia , Síndrome , Conchas Nasais/cirurgia , Procedimentos Cirúrgicos Nasais/efeitos adversos , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/terapia
2.
Nepal J Ophthalmol ; 15(30): 108-115, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38976344

RESUMO

BACKGROUND: Rhino-orbital-cerebral mucormycosis (ROCM) is a rare, opportunistic, angio-invasive, and fatal infection caused by mold fungi of the genera Rhizopus, Mucor, and Rhizomucor. The global incidence of ROCM is 0.005-1.7 per million, with a fatality rate of 46%. Early diagnosis and treatment are crucial for this disease, as a delay of one week can increase the mortality rate to 66%. CASE: A 32-year-old male, a known case of coronavirus disease 2019 (COVID-19) for the past 15 days from Janakpur, Dhanusha, Nepal presented to the emergency department of Dhulikhel Hospital with a sudden onset of blurred vision in the left eye, left-sided ocular pain, and nasal bleeding for the last three days. OBSERVATIONS: The patient was suspected of post-COVID-19 mucormycosis, and a nasal swab for potassium hydroxide (KOH) mount showed hyphae in microscopy. Intravenous and retrobulbar liposomal amphotericin B were administered as medical therapy, along with surgical debridement. A multidisciplinary approach was necessary for the treatment. CONCLUSION: A long-term, multimodal treatment approach involving combined antifungal drug therapy (intravenous liposomal amphotericin B and retrobulbar amphotericin B), and timely surgical debridement leads to an improvement in both short-term and long-term outcomes.


Assuntos
Antifúngicos , COVID-19 , Infecções Oculares Fúngicas , Mucormicose , Doenças Orbitárias , SARS-CoV-2 , Humanos , Mucormicose/diagnóstico , Mucormicose/terapia , Masculino , COVID-19/complicações , COVID-19/diagnóstico , Adulto , Infecções Oculares Fúngicas/diagnóstico , Infecções Oculares Fúngicas/microbiologia , Infecções Oculares Fúngicas/terapia , Infecções Oculares Fúngicas/tratamento farmacológico , Antifúngicos/uso terapêutico , Doenças Orbitárias/diagnóstico , Doenças Orbitárias/microbiologia , Doenças Orbitárias/terapia , Anfotericina B/uso terapêutico , Nepal , Doenças Nasais/microbiologia , Doenças Nasais/diagnóstico , Doenças Nasais/terapia
3.
Medicine (Baltimore) ; 101(2): e28600, 2022 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-35029243

RESUMO

BACKGROUND: From the end of 2019 to now, coronavirus disease 2019 (COVID-19) has put enormous strain on the world's health systems, causing significant deaths and economic losses worldwide. Nasal congestion, one of the symptoms of COVID-19, poses considerable problems for patients. In China, acupuncture has been widely used to treat nasal congestion caused by COVID-19, but there is still a lack of evidence-based medical evaluation. METHODS: According to the retrieval strategies, randomized controlled trials on the acupuncture for COVID-19 nasal congestion were obtained from China National Knowledge Infrastructure, WanFang, VIP, PubMed, Embase, and Cochrane Library, regardless of publication date, or language. Studies were screened based on inclusion and exclusion criteria, and the Cochrane risk bias assessment tool was used to evaluate the quality of the studies. The meta-analysis was performed using Review Manager (RevMan 5.3) and STATA 14.2 software. Ultimately, the evidentiary grade for the results will be evaluated. RESULTS: The study will provide a high-quality and convincing assessment of the efficacy and safety of acupuncture in the treatment of COVID-19's nasal congestion and will be published in peer-reviewed journals. CONCLUSION: Our findings will provide references for future clinical decision and guidance development. PROSPERO REGISTRATION NUMBER: NO.CRD42021299482.


Assuntos
Terapia por Acupuntura , COVID-19/complicações , Doenças Nasais/terapia , Humanos , Metanálise como Assunto , Doenças Nasais/complicações , Projetos de Pesquisa , SARS-CoV-2 , Revisões Sistemáticas como Assunto , Resultado do Tratamento
6.
J Am Anim Hosp Assoc ; 57(3): 114-120, 2021 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-33770179

RESUMO

The purpose of this study was to describe the clinical presentation, imaging findings, and outcome in 10 dogs diagnosed with Rhinosporidium seeberi infections. Histopathology and cytology records were searched at a veterinary teaching hospital and a veterinary diagnostic laboratory to identify dogs with rhinosporidiosis. Medical records were reviewed for clinical, imaging, endoscopic, and surgical findings. Outcome was determined via evaluation of records and, where possible, telephone conversation with the primary care veterinarian and/or owner. Young to middle-aged large-breed dogs with an approximately equal sex distribution were represented. Unilateral signs predominated. Diagnosis was confirmed by histopathology in 9 cases, and cytology was diagnostic in only 1 of 3 cases. Histopathology was superior to cytology. Masses were soft tissue and contrast enhancing with no evidence of bony lysis on computed tomography (2 dogs). Direct or rhinoscopic (2 dogs) visualization revealed white to yellow pinpoint foci. Surgical resection (4 dogs) can result in long-term disease-free periods (up to 2659 days), although repeat surgery can be required. Dapsone was well tolerated in 1 dog, and relapse was not noted despite incomplete surgical resection (follow-up 749 days). Visualization of pale foci on a rostral intranasal mass in an endemic region should prompt consideration of rhinosporidiosis.


Assuntos
Doenças do Cão/diagnóstico , Cavidade Nasal , Doenças Nasais/veterinária , Rinosporidiose/veterinária , Animais , Diagnóstico Diferencial , Doenças do Cão/diagnóstico por imagem , Doenças do Cão/mortalidade , Doenças do Cão/terapia , Cães , Feminino , Masculino , Doenças Nasais/diagnóstico , Doenças Nasais/mortalidade , Doenças Nasais/terapia , Registros/veterinária , Rinosporidiose/diagnóstico , Rinosporidiose/mortalidade , Rinosporidiose/terapia , Tomografia Computadorizada por Raios X
7.
J Laryngol Otol ; 135(2): 110-116, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33563344

RESUMO

BACKGROUND: Nasal lavage is an ancient practice that still has a fundamental role in the management of sinonasal conditions. The history related to these devices is extensive and remarkable. By reviewing it, it is hoped that a broader view can be achieved on what is currently possible with nasal lavage and how advances may be made in the future. METHODS: A careful review of different sources, such as ancient manuscripts, registered patents and scientific papers, was conducted to achieve a thorough examination of the history related to nasal rinsing devices. CONCLUSION: Nasal lavage has evolved significantly since first considered for medical use and has always played a central role in the treatment of patients with sinonasal conditions. Further innovation is still necessary to surmount the shortcomings of current nasal lavage systems.


Assuntos
Desenho de Equipamento/história , Lavagem Nasal/instrumentação , Doenças Nasais/terapia , Seios Paranasais/patologia , História do Século XV , História do Século XVI , História do Século XVII , História do Século XVIII , História do Século XIX , História Antiga , História Medieval , Humanos , Lavagem Nasal/história , Líquido da Lavagem Nasal , Seringas
10.
Int Forum Allergy Rhinol ; 11(6): 984-992, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33151634

RESUMO

BACKGROUND: Individuals affected by empty nose syndrome secondary to turbinate-sparing techniques (ENS-type) experience decreased productivity and lifestyle disruption owing to considerable nasal-associated discomfort. This study aimed to evaluate the effect of psychosomatic intervention on ENS-type. METHODS: A prospective self-controlled study was conducted, and 28 patients suffering from ENS-type who met the diagnostic criteria for somatic symptom disorder (SSD) according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) received cognitive and behavioral therapy (CBT) plus antidepressants. Nasal symptom burden was evaluated using the 25-item Sino-Nasal Outcome Test (SNOT-25). Somatic symptom burden, anxiety severity, and depression severity were assessed by the 25-item Patient Health Questionnaire (PHQ-15), the 9-item PHQ (PHQ-9), and the 7-item Generalized Anxiety Disorder (GAD-7) scale, respectively. Patient assessments were completed prior to treatment and 3 and 12 months after the intervention. RESULTS: The total scores of the SNOT-25 declined posttreatment, showing a significant difference at the 3-month and 12-month follow-ups compared with the baseline scores (p < 0.001). The severity of the 5 most common subjective symptoms, including "nose is too open," "waking up at night," "lack of a good night's sleep," "difficulty falling asleep," and "reduced concentration," declined significantly at 3 and 12 months posttreatment compared to baseline levels. Statistically significant changes in the PHQ-15, PHQ-9, and GAD-7 scores were observed at 3 and 12 months posttreatment compared to baseline scores (p < 0.001). CONCLUSION: This study showed that some patients with ENS-type meeting the diagnostic criteria for SSD might benefit from psychiatric treatment.


Assuntos
Doenças Nasais , Conchas Nasais , Humanos , Doenças Nasais/diagnóstico , Doenças Nasais/terapia , Estudos Prospectivos , Teste de Desfecho Sinonasal , Síndrome , Conchas Nasais/cirurgia
11.
J Craniofac Surg ; 31(7): 1978-1980, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32604314

RESUMO

Nasal cracking is the habit of applying pressure to one's nose until hearing a popping noise or feeling a release of pressure. Clinicians are mostly unaware of it as it is a lesser known habit that has been popularized on social media. Most often it is harmless, however sometimes it can lead to adverse consequences such as pain, bruising, bleeding, and/or breathing problems. In this case study, a patient is evaluated and treated for nasal cracking that led to a septal hematoma.


Assuntos
Hematoma/terapia , Doenças Nasais/terapia , Hábitos , Humanos , Masculino , Septo Nasal , Adulto Jovem
13.
Acta pediatr. esp ; 78(3/4): e74-e81, mar.-abr. 2020. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-202683

RESUMO

INTRODUCCIÓN: Existen pocos estudios sobre la recomendación de soluciones de aguas de mar y el grado de adherencia y satisfacción de los pacientes/usuarios. OBJETIVO: Analizar el perfil de recomendación del médico de los lavados nasales con solución isotónica de agua de mar, el seguimiento y la satisfacción del usuario. MATERIAL Y MÉTODOS: Estudio observacional, epidemiológico, transversal y multicéntrico basado en un registro médico y una encuesta telefónica estructurada a pacientes/usuarios de lavados nasales con agua de mar. RESULTADOS: Participaron 175 médicos (87 pediatras, 53 otorrinolaringólogos, 35 alergólogos) y se entrevistaron por teléfono 1.350 usuarios. Los principales motivos de recomendación: congestión nasal (65,2%), rinitis (34,6%) e higiene (30,6%). La pauta más recomendada es 3 lavados/día durante 3 semanas. El 95% de los usuarios siguió las instrucciones del médico. El principal beneficio es la mejora de la congestión nasal (85,2%), la mucosidad (77,7%) y la dificultad para respirar (72,2%). Un 66,4% refirió haber acortado los días de enfermedad y un 52,8% reducir el uso de medicamentos. La valoración global fue buena o muy buena en el 93,85% de los casos. CONCLUSIONES: El seguimiento del paciente/usuario de la recomendación médica sobre lavados nasales con soluciones de agua de mar es alto y no interfiere de manera importante con su rutina diaria. Sus principales beneficios son la reducción de la congestión nasal, la mucosidad y la dificultad para respirar, así como el acortamiento de los días de enfermedad y el menor consumo de medicamentos. Dos de cada tres lo consideran mejor que el suero fisiológico tradicional


INTRODUCTION: There are few studies on the criteria for recommending the physiological seawater solutions and the adherence and satisfaction of the patients/users. OBJECTIVE: Analyze the medical recommendation profile of nasal washes with isotonic solution of seawater, the follow-up of recommendation and overall satisfaction of the users. Materials and methodology: Observational, epidemiological, cross-sectional and multi-center study based on a medical record and a structured telephone survey of patients/users of nasal washes with isotonic microdiffusion of sea water. RESULTS: A total of 175 physicians participated (87 paediatricians, 53 otolaryngologists and 35 allergists) and 1350 users were interviewed by telephone. The main reasons for recommendation: nasal congestion (65.2%), rhinitis (34.6%) and hygiene (30.6%). The most recommended pattern was 3 washes daily for 3 weeks. 95% of users followed the doctor's instructions. The main benefits were improvement of nasal congestion (85.2%), mucus (77.7%), rhinorrhea (75.6%) and difficulty in breathing (72.2%). 66.4% reported having shortened sick days and 52.8% that had reduced the use of other medications. The overall assessment of the product was good or very good in 93.85% of the cases. CONCLUSIONS: The follow-up by the patient/user of medical recommendation on nasal washes with seawater solutions is high and does not interfere in an important way with the daily routine of patient. The main benefit is the reduction of nasal congestion, mucus and difficulty in breathing, as well as the shortening of sick days and the lower consumption of medications. Two out of three subjects consider their use better than traditional physiological saline


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Adulto Jovem , Adulto , Lavagem Nasal/métodos , Água do Mar , Satisfação do Paciente , Doenças Nasais/terapia , Entrevistas como Assunto , Estudos Transversais , Administração por Inalação , Doenças Nasais/classificação
14.
Dermatol Surg ; 46(7): 904-911, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32079868

RESUMO

BACKGROUND: Few publications have addressed nasal valve (NV) insufficiency as a complication of Mohs micrographic surgery. OBJECTIVE: To comprehensively review the literature and further characterize the causes, prevalence, evaluation, and management of NV insufficiency as it relates to cutaneous oncology. MATERIALS AND METHODS: A PubMed search was completed to identify articles related to the NV in the context of Mohs micrographic surgery, cutaneous oncology, and reconstruction. RESULTS: Nasal valve insufficiency may occur during tumor removal and/or reconstruction. Defect size larger than 1 cm; location on the ala, sidewall, or alar crease; lack of structural support; and poorly planned flaps are the main risk factors for NV insufficiency. Several surgical techniques have been described to avoid and correct this complication. CONCLUSION: Nasal valve insufficiency may be an underrecognized and underreported complication of Mohs micrographic surgery. Nasal valve insufficiency may be identified with relatively simple tests. Knowledge of NV anatomy and preoperative function assessment is essential. Recognition of this potential complication and awareness of its prevention and management may decrease morbidity in patients undergoing cutaneous surgery.


Assuntos
Cirurgia de Mohs/efeitos adversos , Doenças Nasais/etiologia , Neoplasias Nasais/cirurgia , Complicações Pós-Operatórias/etiologia , Humanos , Doenças Nasais/diagnóstico , Doenças Nasais/epidemiologia , Doenças Nasais/terapia , Cuidados Pós-Operatórios , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/terapia
15.
Ann Otol Rhinol Laryngol ; 129(1): 87-90, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31416334

RESUMO

OBJECTIVES: To highlight a severe case of rhinotillexomania (compulsive nasal picking) and its potential to manifest as empty nose syndrome (ENS). METHODS: A single case report with the presentation and management of a patient with severe rhinotillexomania who presented with chronic obstructive symptoms. We review the current literature on rhinotillexomania and ENS. RESULTS: This patient's manifestations mimic the obstructive symptoms of ENS, despite widely patent nasal passages. CONCLUSION: This is the first report of rhinotillexomania manifesting with features of ENS.


Assuntos
Comportamento Compulsivo/complicações , Perfuração do Septo Nasal/etiologia , Idoso , Antibacterianos/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Budesonida/uso terapêutico , Endoscopia , Humanos , Umidificadores , Masculino , Mupirocina/uso terapêutico , Obstrução Nasal , Perfuração do Septo Nasal/diagnóstico , Perfuração do Septo Nasal/terapia , Doenças Nasais/diagnóstico , Doenças Nasais/etiologia , Doenças Nasais/terapia , Síndrome , Irrigação Terapêutica , Tomografia Computadorizada por Raios X
16.
Vet Clin North Am Small Anim Pract ; 50(2): 359-374, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31839206

RESUMO

Nasal disease in dogs is common and is often accompanied by chronic nasal discharge with or without other clinical signs. A thorough history and physical examination often guide the most appropriate choice of diagnostic testing to provide the best chance of attaining a diagnosis as to cause, and therefore, the most appropriate treatment. The purpose of this article is to guide the practitioner through a logical approach to the evaluation of dogs that are presented with signs of nasal disease.


Assuntos
Doenças do Cão/diagnóstico , Doenças Nasais/veterinária , Animais , Doenças do Cão/patologia , Doenças do Cão/terapia , Cães , Feminino , Masculino , Doenças Nasais/diagnóstico , Doenças Nasais/patologia , Doenças Nasais/terapia , Neoplasias Nasais/patologia , Neoplasias Nasais/veterinária
17.
Rev. bras. cir. plást ; 34(4): 576-581, oct.-dec. 2019. ilus, tab
Artigo em Inglês, Português | LILACS | ID: biblio-1047935

RESUMO

Introdução: A rinoplastia é uma cirurgia que muitas vezes apresenta resultados imprevisíveis, mesmo em mãos de cirurgiões experientes. Neste sentido, a rinomodelação com preenchedores é um procedimento não-cirúrgico para corrigir pequenas alterações externas nasais em casos específicos. Métodos: Os autores descrevem a técnica de aplicação de preenchedores (ácido hialurônico ou hidroxiapatita de cálcio) para modelação nasal. Foram incluídos todos os pacientes submetidos ao preenchimento nasal, entre 2009 e 2012. Foi avaliado o edema da ponta nasal, a dor e o grau de satisfação dos pacientes com o resultado. Resultados: Foram incluídos 39 pacientes no estudo. Com relação aos desfechos analisados com ácido hialurônico: 52% apresentaram edema leve; 74% tiveram dor leve; 15% se mostraram muito satisfeitos e 74% satisfeitos com o resultado. Com relação aos pacientes submetidos à rinomodelação com hidroxiapatita de cálcio: 67% apresentaram edema moderado; 50% dor moderada; 17% dor intensa e 84% se mostraram satisfeitos com o resultado. Conclusão: A rinomodelação com preenchedores reabsorvíveis é um procedimento simples, com resultados estéticos aceitáveis, sendo necessário um profundo conhecimento anatômico para diminuir o risco de complicações.


Introduction: Rhinoplasty often leads to unpredictable results, even in the hands of experienced surgeons. However, in specific cases, rhinomodelation with fillers, a non-surgical procedure to correct minor nasal external changes, can be used. Methods: This study describes the application technique of fillers (hyaluronic acid or calcium hydroxyapatite) for nasal modeling. Patients undergoing nasal filling between 2009 and 2012 were included. Edema of the nasal tip, pain, and the degree of patient satisfaction with the outcome were assessed. Results: Thirty-nine patients were included in the study. Regarding the outcomes of rhinomodelation with hyaluronic acid, 52% patients presented with mild edema, 74% had mild pain, 15% were very satisfied, and 74% were satisfied with the result. For the outcomes of rhinomodelation with calcium hydroxyapatite, 67% patients presented with moderate edema, 50% had moderate pain; 17% had severe pain, and 84% were satisfied with the result. Conclusion: Rhinomodelation with resorbable fillers is a simple procedure with acceptable esthetic results. However, a deep anatomical knowledge is necessary to decrease the risk of complications.


Assuntos
Humanos , Adulto , Pessoa de Meia-Idade , História do Século XXI , Complicações Pós-Operatórias , Rinoplastia , Nariz , Deformidades Adquiridas Nasais , Doenças Nasais , Preenchedores Dérmicos , Complicações Pós-Operatórias/terapia , Rinoplastia/métodos , Nariz/cirurgia , Nariz/lesões , Deformidades Adquiridas Nasais/cirurgia , Deformidades Adquiridas Nasais/reabilitação , Doenças Nasais/complicações , Doenças Nasais/terapia , Preenchedores Dérmicos/efeitos adversos , Preenchedores Dérmicos/uso terapêutico
19.
Zhonghua Yan Ke Za Zhi ; 55(8): 629-633, 2019 Aug 11.
Artigo em Chinês | MEDLINE | ID: mdl-31422642

RESUMO

Mucormycosis is a rare, rapidly progressive life threatening opportunistic fungal infection, with rhinocerebral mucormycosis being the most common type. Rhinocerebral mucormycosis usually presents symptoms similar to sinusitis and orbital cellulitis during its early stage,which often leads to a misdiagnosis at the very beginning,and progresses rapidly to endophthalmitis,blindness,sclera perforation, eyeball atrophy, and even gets the central nervous system involved, thus leading to death. Mucormycosis is particularly common in patients with poor glycemic control, ketoacidosis and immunosuppression. The purpose of this review is to highlight the predisposing factors, infection pathway, pathogenesis, clinical presentations, diagnosis, and management of rhinocerebral mucormycosis, hence further promote the early diagnosis and immediate treatment of the disease. (Chin J Ophthalmol,2019,55:629-633).


Assuntos
Encefalopatias , Mucormicose , Doenças Nasais , Encefalopatias/diagnóstico , Encefalopatias/terapia , Fungos , Humanos , Mucormicose/diagnóstico , Mucormicose/terapia , Doenças Nasais/diagnóstico , Doenças Nasais/terapia
20.
Am J Otolaryngol ; 40(4): 609-611, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31109807

RESUMO

The management of invasive fungal sinusitis differs greatly from the management of herpes simplex virus (HSV) of the nose in immunocompromised patients. However, the diagnosis may be uncertain and a delay in treatment can lead to mortality. Here we describe the successful medical management of a series of immunocompromised pediatric patients with HSV lesions of the nose with the initial concern for invasive fungal sinusitis. The diagnosis of HSV herpes was supported by positive polymerase chain reaction (PCR) testing of the nasal lesion. To our knowledge, these are the first cases described in the pediatric literature, emphasizing the need to include this entity on the differential.


Assuntos
Herpes Simples/diagnóstico , Doenças Nasais/diagnóstico , Aciclovir/administração & dosagem , Adolescente , Adulto , Antivirais/administração & dosagem , Criança , Diagnóstico Diferencial , Feminino , Herpes Simples/patologia , Herpes Simples/terapia , Herpes Simples/virologia , Humanos , Hospedeiro Imunocomprometido , Infusões Intravenosas , Infecções Fúngicas Invasivas/patologia , Leucemia de Células B , Masculino , Doenças Nasais/patologia , Doenças Nasais/terapia , Doenças Nasais/virologia , Seios Paranasais , Reação em Cadeia da Polimerase , Leucemia-Linfoma Linfoblástico de Células Precursoras , Sinusite/microbiologia , Sinusite/patologia , Resultado do Tratamento
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