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J Neurol Sci ; 270(1-2): 209-10, 2008 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-18456282

RESUMO

A 40-year-old man was admitted to our department, because of sudden onset of dysphagia, hoarseness, left neck pain and headache. There were no skin lesions. On neurological examination, there were paralysis of the left soft palate and constrictor muscles of the pharynx, weakness of the left sternocleidomastoid and left upper trapezius. In cerebrospinal fluid (CSF) examination, cell count and protein concentration were elevated. Antibody titer to varicella zoster virus (VZV) was elevated in both the serum and CSF. And VZV-DNA was detected by PCR from CSF. Gd enhanced MRI showed the nodular lesion at the left jugular foramen. The diagnosis of Vernet's syndrome (VS) associated with VZV infection was made. The patient's symptoms were immediately improved with 30 mg of prednisone and 3 g of varaciclovir daily for 14 days. Only a few cases of VS due to VZV have been reported previously. Our case is the first case that detected VZV-DNA in CSF by PCR.


Assuntos
Encefalite por Varicela Zoster/complicações , Doenças do Nervo Glossofaríngeo/etiologia , Doenças do Nervo Vago/etiologia , Adulto , Anticorpos/sangue , Anticorpos/líquido cefalorraquidiano , Encefalite por Varicela Zoster/metabolismo , Encefalite por Varicela Zoster/patologia , Doenças do Nervo Glossofaríngeo/metabolismo , Doenças do Nervo Glossofaríngeo/patologia , Doenças do Nervo Glossofaríngeo/virologia , Herpesvirus Humano 3/imunologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Doenças do Nervo Vago/metabolismo , Doenças do Nervo Vago/patologia , Doenças do Nervo Vago/virologia
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