[Investigation of Tahyna virus infection among unknown fever cases in Xinjiang, China].

To investigate the infection status and the spatial distribution of Tahyna virus infection among unknown fever cases in Xinjiang, China. Sera samples of unknown fever cases from Kashi in southern Xin-jiang and Yili in northern Xinjiang were tested against Tahyna virus by IFA. Partial positive cases were tested against Tahyna virus/Snowshoe hare virus/Inkoo virus parrelled. Finally, 742 sera samples of unknown fever cases were collected from Kashi, Southern Xinjiang in 2007-2008, the positive rate of IgM antibody against Tahyna virus was 5.3%, the positive rate of IgG antibody against Tahyna virus was 18.3%. 222 sera samples of unknown fever cases were collected from Yili, Northern Xinjiang in 2008, no positive case of IgM antibody against Tahyna was found. 10 cases showed antibody neutralization against Tahyna virus by plaque reduction neutralization test. Our results demonstrate that there is current infection and past infection of Tahyna virus among Southern Xinjiang residents.

[Outcomes and prognosis of diseases caused by Inkoo and Tahyna viruses]. / Iskhody i prognoz zabolevanii, vyzyvaemykh virusami inko i tiaginia.

The outcomes of diseases caused by Inkoo and Tahyna viruses are favorable. No lethal cases were observed. Altogether 16.7% of convalescents after the febrile form of the disease and 30.7% convalescents after the neuroinfections form develop 1 to 2.5 years after the disease (follow-up period) asthenoneurologic disturbances and microfocal neurologic symptoms. Blood sera of 118 patients with chronic neurologic diseases were tested in the neutralization test with Inkoo and Tahyna viruses. Summary antibodies to Inkoo and Tahyna viruses were detected in 26 (70.3%) of 37 examined patients with disseminated encephalomyelitis. The findings point to necessity of further study of the possible role of California encephalitis group viruses in the etiology of chronic neuroviral infections.