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1.
Artigo em Russo | MEDLINE | ID: mdl-10925884

RESUMO

In tick-borne encephalitis certain immunopathological reactions develop in the tissues of the central nervous system; alpha 2-macroglobulin may serve as the marker of the activity of these reactions. The dynamic study of liquor taken from 16 patients with the meningeal and focal forms of tick-borne encephalitis (TBE), 8 patients with severe craniocerebral traumas accompanied by meningitis and 10 patients with osteochondrosis was made. As revealed in this study, in TBE patients the level of alpha 2-macroglobulin increases 3.5-fold and remains stable during the acute period of the disease.


Assuntos
Encéfalo/imunologia , Encefalite Transmitida por Carrapatos/imunologia , alfa-Macroglobulinas/imunologia , Doença Aguda , Biomarcadores/líquido cefalorraquidiano , Traumatismos Craniocerebrais/líquido cefalorraquidiano , Traumatismos Craniocerebrais/complicações , Traumatismos Craniocerebrais/imunologia , Encefalite Transmitida por Carrapatos/líquido cefalorraquidiano , Humanos , Meningite/líquido cefalorraquidiano , Meningite/etiologia , Meningite/imunologia , Meningoencefalite/líquido cefalorraquidiano , Meningoencefalite/etiologia , Meningoencefalite/imunologia , Osteocondrite/líquido cefalorraquidiano , Osteocondrite/imunologia , Espondilite/líquido cefalorraquidiano , Espondilite/imunologia , alfa-Macroglobulinas/líquido cefalorraquidiano
2.
Zh Vopr Neirokhir Im N N Burdenko ; (1): 25-7; discussion 27-8, 1999.
Artigo em Russo | MEDLINE | ID: mdl-10335573
3.
Artigo em Russo | MEDLINE | ID: mdl-7856372

RESUMO

Spontaneous and initiated by hydrogen peroxide chemiluminescence was evaluated before and after freezing of the CSF from 20 patients with various spinal tumors and 10 controls with intervertebral lumbar osteochondrosis. The intensity of the above chemiluminescence was found significantly different in tumors and osteochondrosis. Cryotreatment induced marked changes in CSF chemiluminescence, especially in extramedullary spinal tumors. CSF treatment with hydrogen peroxide entailed alterations in free radical oxidation which can serve an additional criterion in combined diagnosis of spinal cord tumors.


Assuntos
Peróxidos/líquido cefalorraquidiano , Neoplasias da Medula Espinal/líquido cefalorraquidiano , Líquido Cefalorraquidiano/efeitos dos fármacos , Radicais Livres , Congelamento , Humanos , Peróxido de Hidrogênio/farmacologia , Vértebras Lombares , Medições Luminescentes , Osteocondrite/líquido cefalorraquidiano , Espondilite/líquido cefalorraquidiano
4.
Artigo em Russo | MEDLINE | ID: mdl-7856374

RESUMO

Pre- and postoperative immunochemical indices of cerebrospinal fluid (CSF) were investigated in 10 patients with fibrillary-protoplasmic astrocytoma and 10 patients with glioblastoma multiforme. Malignant neoplastic developments in the brain are associated with appearance of marked humoral reaction. Tumor-specific CSF changes observed comprise registration of ceruloplasmin immunomodulating proteins and alpha 2-macroglobulin. It is emphasized that biochemical antioxidant, antiprotease, energy-supplying systems are related directly to humoral immune reactions in the process of relevant postoperative rehabilitation.


Assuntos
Astrocitoma/líquido cefalorraquidiano , Astrocitoma/imunologia , Neoplasias Encefálicas/líquido cefalorraquidiano , Neoplasias Encefálicas/imunologia , Adolescente , Adulto , Formação de Anticorpos , Astrocitoma/cirurgia , Neoplasias Encefálicas/cirurgia , Feminino , Humanos , Imuno-Histoquímica , Vértebras Lombares , Masculino , Pessoa de Meia-Idade , Neuroimunomodulação , Osteocondrite/líquido cefalorraquidiano , Osteocondrite/imunologia , Espondilite/líquido cefalorraquidiano , Espondilite/imunologia , Fatores de Tempo
6.
J Neurosurg ; 44(6): 687-97, 1976 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-1271089

RESUMO

Cerebrospinal fluid (CSF) pressure was recorded in 149 patients and arterial blood pressure (BP) in 11 patients while moving between lateral and sitting positions. Rapid tilting initiated waves in BP and CSF filling pressure. The postural CSF pressure wave manifested itself either as a transient or as a stationary wave similar to a plateau wave. When patients sat up, transient waves had amplitudes up to 550 and stationary waves up to 1000 mm H2O. When they lay down, transient waves had amplitudes up to 800 mm H2O. Stationary waves were found only among patients with elevated intracranial pressure and a diseased brain. The waves were mainly caused by changes in cerebral blood volume probably reflecting the postural BP wave and brain autoregulation. Most patients with stationary and large transient waves also manifested clinical symptoms. These symptoms were aggravated when a craniospinal block developed in the sitting position, and were reduced or avoided when the tilting was performed slowly over 2 to 3 minutes.


Assuntos
Pressão Intracraniana , Postura , Pressão Sanguínea , Ventrículos Cerebrais , Líquido Cefalorraquidiano/fisiologia , Vértebras Cervicais , Humanos , Hidrocefalia/líquido cefalorraquidiano , Pressão Hidrostática , Região Lombossacral , Movimento , Pressão , Espondilite/líquido cefalorraquidiano , Hemorragia Subaracnóidea/líquido cefalorraquidiano , Fatores de Tempo
7.
J Neurosurg ; 44(6): 698-705, 1976 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-1271090

RESUMO

Lumbar cerebrospinal fluid (CSF) pressure was recorded in 116 adult neurosurgical patients in the lateral and sitting positions. The level of zero CSF pressure while in the sitting position (ZPS) and hydrostatic indifferent point (HIP) for lateral and sitting positions were determined and referred to the craniospinal axis. In control patients ZPS was located mainly at the upper cervical region, and showed nearly the same variation and frequency distribution as CSF pressure in the lateral position when efforts were made to reduce sources of error and there was no orthostatic change in CSF filling pressure. Under these circumstances ZPS may be used as a variable comparable from one subject to another. In control patients the HIP was located between C-6 and T-5. In 25 hydrocephalic patients, shunting resulted in a mean caudal shift of ZPS of 244 mm, and a mean pressure fall of 126 mm H2O in the lateral position. This difference was due to a caudal shift of HIP on shunting. A caudally located ZPS was found in patients with complete cervical subarachnoid block. Prevention and treatment of CSF leakage cranial to HIP is discussed.


Assuntos
Pressão Hidrostática , Pressão Intracraniana , Postura , Pressão , Pressão Sanguínea , Líquido Cefalorraquidiano/fisiologia , Derivações do Líquido Cefalorraquidiano , Vértebras Cervicais , Humanos , Hidrocefalia/líquido cefalorraquidiano , Movimento , Crânio/anormalidades , Espondilite/líquido cefalorraquidiano , Fatores de Tempo
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