RESUMO
OBJECTIVE: The aim of this study was to compare the prevalence of Candida spp. in diabetics and nondiabetics with and without denture stomatitis (DS). STUDY DESIGN: Mycologic samples were taken from the dentures of 90 healthy subjects (control group [CG]), 80 denture stomatitis nondiabetics (DSND), and 40 denture stomatitis diabetics (DSD; well controlled type 2) for identification of Candida spp. Results were analyzed by Fisher exact test, Bonferroni-corrected confidence interval, and χ(2) test (α = .05). RESULTS: Candida albicans was the predominant species isolated (81.9%; P < .016), with C. tropicalis and C. glabrata demonstrating similar prevalence (15.71% and 15.24%, respectively). The prevalence of C. albicans and C. tropicalis in the DS groups were significantly higher (P < .01) than in the CG. The prevalence of C. tropicalis significantly increased with the highest degree of inflammation (P < .05). CONCLUSIONS: The prevalence of Candida spp. was similar between diabetic and nondiabetic patients with DS. Candida tropicalis may play a role in the progression of DS.
Assuntos
Candida/isolamento & purificação , Prótese Dentária/microbiologia , Dentaduras/efeitos adversos , Diabetes Mellitus Tipo 2/microbiologia , Estomatite sob Prótese/microbiologia , Idoso , Glicemia/metabolismo , Candida/classificação , Estudos de Casos e Controles , Distribuição de Qui-Quadrado , Estudos Transversais , Prótese Dentária/efeitos adversos , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Boca/microbiologia , Valores de Referência , Fatores Sexuais , Estatísticas não Paramétricas , Estomatite sob Prótese/sangue , Estomatite sob Prótese/complicaçõesRESUMO
Denture stomatitis is a primarily oral disease that affects denture wearers. The presence of Candida albicans in the palatal mucosa, on the internal surface of the maxillary denture, and in the blood of patients with denture stomatitis was evaluated. Although the results did not show C albicans in the bloodstream of patients, a strong relationship between denture stomatitis and Candida sp was confirmed for both the palatal mucosa and maxillary denture.