Vascular trauma associated with routine spinal anaesthesia.

Samples of cerebrospinal fluid obtained from 130 patients undergoing spinal anaesthesia were examined microscopically. Subarachnoid puncture was performed using either a 25G Whitacre or 25G Quincke spinal needle. Two samples were collected from each patient and the red blood cell count of the second sample collected was taken as a measure of the vascular trauma associated with the procedure. Red blood cells were seen in 50 (38%) of these samples, of which 18 (14%) contained > 100 red blood cells.mm-3. Paraesthesia was felt by 11 (8.5%) patients and the occurrence of paraesthesia was associated with significantly raised red blood cell counts (p < 0.0001). There was also a correlation between the number of needle passes made at lumbar puncture and the red blood cell count in the sample (p < 0. 0001). Neither spinal needle type nor antiplatelet drug therapy influenced red blood cell counts (p = 0.66 and 0.37, respectively). These findings suggest that routine spinal anaesthesia is often complicated by minor degrees of vascular trauma, especially when paraesthesiae or technical difficulty occur at subarachnoid puncture.

[Role of endogenous neurohumoral factors in mechanisms of the pathogenesis and compensation of unilateral movement disorders after serial removal of the motor neocortex]. / Rol' éndogennykh neirogumoral'nykh faktorov v mekhanizmakh patogeneza i kompensatsii odnostoronnikh dvigatel'nykh rasstroistv posle seriinykh udalenii motornogo neokorteksa.

The role of neurohumoral factors in the mechanisms of restoring the lost motor functions after two successive unilateral removals of the neocortex motor region, was studied. The dynamics of the restoring correlated with the posture asymmetry factor (PAF) activity in the CSF. PAF activity was reduced during the restoring by an inactivation factor (FI). Periods of restoration after the 2nd extirpation and inactivation of PAF were shorter than after the 1st one. The existence of the FI before the 2nd extirpation may account for this phenomenon.