CT-guided biopsy of metastatic sacral tumors.

Between June 8, 1985 and January 29, 1986, the authors performed five CT-guided needle biopsies of suspicious sacral lesions. In each of the five cases, these biopsies allowed the acquisition of specimens suitable for definitive pathologic diagnosis. Three cases of metastatic adenocarcinoma, one case of desmoplastic fibroma, and one case of chronic inflammatory changes were noted. In the case involving chronic inflammatory changes, subsequent open biopsy was performed, confirming the inflammatory changes and absence of neoplasm. The authors conclude that percutaneous CT-guided biopsy of sacral lesion can be performed safely and rapidly, and allows accurate diagnosis and treatment of sacral lesions.

[Juvenile aponeurotic fibroma (Keasbey tumor) with metastatic course. Apropos of a case]. / Fibrome aponévrotique juvénile (tumeur de Keasbey) a évolution métastatique. A propos d'un cas.

Juvenile aponeurotic fibroma, isolated in 1953 by Louisa Keasbey is a rare tumour which is characterized by its recurrence and infiltration, but which has no tendency to metastasis. The case we report differs in its long-term outcome. The tumour diagnosed in a seven-year-old child has recurred locally for seven years, necessitated hand amputation, and finally developed a fibroblastic process extending to lung and pleura which caused the child's death. This new finding in Keasbey's disease led us to reconsider the nosological situation in juvenile fibromatoses and its reputation for benignity.

[Juvenile aponeurotic fibroma (Keasbey's tumor) with metastatic progression. Apropos of a case]. / Fibrome aponévrotique juvénile (tumeur de Keasbey) à evolution métastatique. A propos d'un cas.

The juvenile aponeurotic fibroma, isolated in 1953 by Louisa Keasbey is a rare tumour which is characterized by its recurrence and infiltration, but which has no tendency to metastasis. The case we report differs in its long-term outcome. The tumour diagnosed in a seven-year-old child has recurred locally for seven years, necessitated hand amputation, and finally developed a fibroblastic process extending to lung and pleura which caused the child's death. After this new finding in Keasbey's disease, we are led to reconsider the nosological situation in juvenile fibromatoses and its character of benign disease.

[Clinico-morphologic analysis of primary and metastatic tumors of the heart]. / Kliniko-morfologicheskii analiz pervichnykh i metastaticheskikh opukholei serdtsa.

The analysis of 7358 autopsies performed in 1966-1986 showed that cardiac tumors were detected in 94 cases (1.27%) and accounted for 4.9% of cancer and 5.48% of cardiac disease cases. Detailed characteristics are provided for 9 primary tumors, of these 3 were assessed clinically and morphologically, (left ventricular elastofibroma, left ventricular pleomorphic rhabdomyosarcoma, left atrial embryonal rhabdomyosarcoma). Primary metastases of pulmonary localization were recorded in 47.9% of cases. Metastatic involvement of the heart presented in 85 cases (1.15% of autopsies, 4.43% of cancer cases, 5% of cardiac affections, 90.42% of cardiac tumors). Cardiac compartments were evaluated for the frequency of tumor emergence.

Metastatic atypical fibroxanthoma of skin.

Metastases from an atypical fibroxanthoma of skin have been reported but are very few in the literature. We had a personal case which, originally localized on the nostril, gave metastases to the cervical regional lymph node with no local recurrence. We examined both the primary and metastatic tumor by conventional histological stains and by immunoperoxidase technique to localize lysozyme, alpha-1-antitrypsin, ferritin and factor VIII antigens. The results show a clear correspondence between the primary and metastatic tumor.

[Applicability of nuclear spin tomography to heart diseases]. / Einsatzmöglichkeiten der Kernspintomographie bei Erkrankungen des Herzens.

Thirty-one patients with abnormalities of the heart and ten controls were examined by ECG-triggered nuclear resonance tomography. All patients had previously been completely investigated. Chamber sizes and mural thickness could be reliably demonstrated and, in addition, it was possible to show areas which could not be easily investigated by echocardiography. Visualisation of the valves was limited, but intra- and para-cardial lesions could be differentiated by a double echo technique. Absence and defects of septa could be shown exactly, as well as accurate demonstration of the relationship of the large vessels to the cardiac chambers.

Desmoid tumor--review and follow-up of ten cases.

Ten cases of desmoid tumor, diagnosed, treated, and followed during the past 11 years, were reviewed and the patients reexamined. Two were up to 3 years, two up to 5 years, and four up to 11 years after excision. The remaining two patients were lost to follow-up. The 10 patients included one male and nine females; six females were of childbearing age and three were postmenopausal. In four females the desmoid tumor was located near various surgical scars. In the one recurrent desmoid it was most probably related to both repeated traumatization of the abdominal wall due to pregnancies and hyperestrogenism. All the surgical margins of resection were microscopically involved by the process. An open liver biopsy, performed simultaneously with the excision of the recurrent desmoid, showed benign nodular hyperplasia compatible with hyperestrogenism. Estrogen and progesterone receptors of this desmoid were negative. In the present series follow-up revealed, in contrast to general agreement, that in spite of incomplete excision, the recurrence rate was low. We suggest that the surgical approach to desmoid tumors could be less radical, except possibly for lesions in patients with multiple causative factors.

A multifocal extra-abdominal desmoid tumour.

The literature on multifocal aggressive fibromatosis is reviewed and the fifth case recorded is reported. It conforms with the histopathological criteria for aggressive fibromatosis. Conservative local excision and radiotherapy have controlled the disease with preservation of a functioning limb.

Cemento-ossifying fibroma of the orbit.

Cemento-ossifying fibroma presents with ophthalmic symptoms and signs rarely. We report the clinical and pathological findings in a case of cemento-ossifying fibroma of the right maxilla with extension into the orbital floor causing intermittent vertical diplopia, proptosis, and upward displacement of the globe. Compression of the nasolacrimal duct produced epiphora early in the course of the disease. Fibrous dysplasia has often been diagnosed in other cases of benign monostotic fibro-osseous conditions. Ossifying fibroma is easily confused with fibrous dysplasia. The histopathological difference between the two lesions is described.