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1.
PLoS One ; 14(7): e0218464, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31291265

RESUMO

There is evidence that replacing saturated fat (SFA) with polyunsaturated fat (PUFA) lowers ischemic heart disease (IHD). In order to improve the population's diet, the World Health Organization has called for the taxation of foods that are high in SFA. We aimed to assess the potential health gains of a European fat tax by applying the SFA intake reduction that has been observed under the Danish fat tax to six other European countries. For each country, we created a fat tax scenario with a decreased SFA intake and a corresponding increase in PUFA. We compared this fat tax scenario to a reference scenario with no change in SFA intake, and to a guideline scenario with a population-wide SFA intake in line with dietary recommendations. We used DYNAMO-HIA to dynamically project the policy-attributable IHD cases of these three scenarios 10 years into the future. A fat tax would reduce prevalent IHD cases by a minimum of 500 and 300 among males and females in Denmark, respectively, up to a maximum of 5,600 and 4,000 among males and females in the UK. Thereby, the prevented IHD cases under a fat tax scenario would correspond to between 11.0% (in females in the Netherlands) and 29.5% (in females in Italy) of the prevented IHD cases under a guideline scenario, which represents the maximum preventable disease burden. Henceforth, our quantification of beneficial health impacts makes the case for the policy debate on fat taxes.


Assuntos
Gorduras na Dieta/efeitos adversos , Isquemia Miocárdica/etiologia , Isquemia Miocárdica/prevenção & controle , Dieta/economia , Dieta/métodos , Dieta Hiperlipídica/efeitos adversos , Dieta Hiperlipídica/economia , Gorduras na Dieta/economia , Gorduras Insaturadas na Dieta/economia , Europa (Continente) , Feminino , Avaliação do Impacto na Saúde , Política de Saúde , Humanos , Masculino , Fatores de Risco , Impostos
2.
J Biosci Bioeng ; 128(1): 98-102, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30745064

RESUMO

Biodiesel production depends to a great extent on the use of cheap raw materials, since biodiesel itself is a mass product, not a high-value product. New processing methods, such as micro-flow continuous processing combined with enzymatic catalysis, open doors to the latter. As reported here, the window of opportunity in enzyme-catalyzed biodiesel production is the conversion of waste cooking oil. The main technological challenge for this is to obtain efficient immobilization of the lipase catalyst on beads. The beads can be filled into tubular reactors where designed packed-bed provide porous channels, forming micro-flow. It turns out, that in this way, the immobilization costs become the decisive economic factor. This paper reports a solution to that issue. The use of oil cake enables economic viability, which is not given by any of the commercial polymeric substrates used so far for enzyme immobilization. The costs of immobilization are mirrored in the earnings and cash flow of the new biotechnological process.


Assuntos
Biocombustíveis , Reatores Biológicos , Biotecnologia/economia , Gorduras Insaturadas na Dieta , Enzimas Imobilizadas/metabolismo , Lipase/metabolismo , Biocombustíveis/análise , Biocombustíveis/economia , Reatores Biológicos/economia , Biotecnologia/instrumentação , Biotecnologia/métodos , Catálise , Culinária , Análise Custo-Benefício , Gorduras Insaturadas na Dieta/economia , Gorduras Insaturadas na Dieta/metabolismo , Enzimas Imobilizadas/economia , Esterificação , Humanos , Dispositivos Lab-On-A-Chip/economia , Microtecnologia/instrumentação , Microtecnologia/métodos , Óleos de Plantas/química , Óleos de Plantas/metabolismo
3.
J Nutr Biochem ; 51: 99-104, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-29125992

RESUMO

At present, high-density lipoprotein (HDL) function is thought to be more relevant than HDL cholesterol quantity. Consumption of olive oil phenolic compounds (PCs) has beneficial effects on HDL-related markers. Enriched food with complementary antioxidants could be a suitable option to obtain additional protective effects. Our aim was to ascertain whether virgin olive oils (VOOs) enriched with (a) their own PC (FVOO) and (b) their own PC plus complementary ones from thyme (FVOOT) could improve HDL status and function. Thirty-three hypercholesterolemic individuals ingested (25 ml/day, 3 weeks) (a) VOO (80 ppm), (b) FVOO (500 ppm) and (c) FVOOT (500 ppm) in a randomized, double-blind, controlled, crossover trial. A rise in HDL antioxidant compounds was observed after both functional olive oil interventions. Nevertheless, α-tocopherol, the main HDL antioxidant, was only augmented after FVOOT versus its baseline. In conclusion, long-term consumption of phenol-enriched olive oils induced a better HDL antioxidant content, the complementary phenol-enriched olive oil being the one which increased the main HDL antioxidant, α-tocopherol. Complementary phenol-enriched olive oil could be a useful dietary tool for improving HDL richness in antioxidants.


Assuntos
Antioxidantes/uso terapêutico , Gorduras Insaturadas na Dieta/uso terapêutico , Hipercolesterolemia/dietoterapia , Lipoproteínas HDL/sangue , Azeite de Oliva/uso terapêutico , Fenóis/uso terapêutico , Biomarcadores/sangue , Estudos Cross-Over , Gorduras Insaturadas na Dieta/economia , Método Duplo-Cego , Feminino , Ingredientes de Alimentos/economia , Qualidade dos Alimentos , Indústria de Processamento de Alimentos/economia , Frutas/química , Humanos , Hipercolesterolemia/sangue , Resíduos Industriais/economia , Lipoproteínas HDL/química , Masculino , Pessoa de Meia-Idade , Olea/química , Azeite de Oliva/economia , Fenóis/economia , Extratos Vegetais/economia , Extratos Vegetais/uso terapêutico , Folhas de Planta/química , Espanha , Thymus (Planta)/química , alfa-Tocoferol/análise , alfa-Tocoferol/sangue
4.
Food Chem Toxicol ; 83: 61-7, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26072099

RESUMO

This work studies on the quantitative analysis and health risk assessment of polycyclic aromatic hydrocarbons (PAHs) in edible vegetable oils in Shandong, China. The concentrations of 15 PAHs in 242 samples were determined by high performance liquid chromatography coupled with fluorescence detection. The results indicated that the mean concentration of 15 PAHs in oil samples was 54.37 µg kg(-1). Low molecular weight PAH compounds were the predominant contamination. Especially, the carcinogenic benzo(a)pyrene (BaP) was detected at a mean concentration of 1.28 µg kg(-1), which was lower than the limit of European Union and China. A preliminary evaluation of human health risk assessment for PAHs was accomplished using BaP toxic equivalency factors and the incremental lifetime cancer risk (ILCR). The ILCR values for children, adolescents, adults, and seniors were all larger than 1 × 10(-6), indicating a high potential carcinogenic risk on the dietary exposed populations.


Assuntos
Carcinógenos Ambientais/toxicidade , Gorduras Insaturadas na Dieta/efeitos adversos , Contaminação de Alimentos , Inspeção de Alimentos/métodos , Mutagênicos/toxicidade , Óleos de Plantas/efeitos adversos , Hidrocarbonetos Policíclicos Aromáticos/toxicidade , Benzo(a)pireno/análise , Benzo(a)pireno/química , Benzo(a)pireno/toxicidade , Carcinógenos Ambientais/análise , Carcinógenos Ambientais/química , China , Cromatografia Líquida de Alta Pressão , Gorduras Insaturadas na Dieta/análise , Gorduras Insaturadas na Dieta/economia , Gorduras Insaturadas na Dieta/normas , União Europeia , Guias como Assunto , Humanos , Limite de Detecção , Peso Molecular , Mutagênicos/análise , Mutagênicos/química , Óleo de Amendoim , Óleos de Plantas/química , Óleos de Plantas/economia , Óleos de Plantas/normas , Hidrocarbonetos Policíclicos Aromáticos/análise , Hidrocarbonetos Policíclicos Aromáticos/química , Reprodutibilidade dos Testes , Medição de Risco , Poluentes do Solo/análise , Poluentes do Solo/química , Poluentes do Solo/toxicidade , Espectrometria de Fluorescência
5.
Food Chem Toxicol ; 83: 68-75, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26070504

RESUMO

Monitoring of food contamination from bisphenols is a necessary process for the consumers' risk assessment. A method for the quali-quantitative analysis of Bisphenol A (BPA), Bisphenol B (BPB), Bisphenol A Diglycidyl Ether (BADGE), and Bisphenol F Diglycidyl Ether (BFDGE), by liquid chromatography with fluorescence detection (LC-FD), was performed and validated for their determination in 33 samples of tuna fish, canned in either oil or aqueous medium. Samples were collected in Italian markets. Tuna and the correspondent preservation medium were analyzed separately. Detected levels of bisphenols ranged from 19.1 to 187.0 ng/g in tuna matrix and from 6.3 to 66.9 ng/mL in oil medium. No bisphenols were found in aqueous medium. At least one of the analytes was found in 83% of the tuna samples in oil medium, whereas tuna samples in aqueous medium showed BPA alone in 67% of samples. 21% of the oil medium samples resulted positive for at least one bisphenol. On the basis of measured concentrations and general daily ingestion rate of canned tuna fish, the probable daily intake of BPA for Italian population was calculated.


Assuntos
Compostos Benzidrílicos/análise , Disruptores Endócrinos/análise , Poluentes Ambientais/análise , Contaminação de Alimentos , Alimentos em Conserva/análise , Fenóis/análise , Alimentos Marinhos/análise , Atum , Animais , Compostos Benzidrílicos/toxicidade , Cromatografia Líquida de Alta Pressão , Gorduras Insaturadas na Dieta/análise , Gorduras Insaturadas na Dieta/economia , Disruptores Endócrinos/toxicidade , Poluentes Ambientais/toxicidade , Compostos de Epóxi/análise , Compostos de Epóxi/toxicidade , Inspeção de Alimentos/métodos , Alimentos em Conserva/economia , Humanos , Itália , Limite de Detecção , Fenóis/toxicidade , Óleos de Plantas/química , Óleos de Plantas/economia , Reprodutibilidade dos Testes , Alimentos Marinhos/economia , Espectrometria de Fluorescência , Espectrometria de Massas por Ionização por Electrospray , Espectrometria de Massas em Tandem
6.
Artigo em Inglês | MEDLINE | ID: mdl-26010536

RESUMO

Cu-pyropheophytin a, the major Cu-pigment of Cu-chlorophyll, was determined in edible oil by high-resolution mass spectrometry with a high-performance liquid chromatography-quadrupole (HPLC-Q)-Orbitrap system and by HPLC coupled with a photodiode-array detector. Respective limit of detection and limit of quantification levels of 0.02 µg/g and 0.05 µg/g were obtained. Twenty-nine commercial oil products marked as olive oil, grapeseed oil and blended oil, all sourced directly from a food company that committed adulteration with Cu-chlorophyll, were investigated. In this company, four green dyes illegally used in oils were seized during factory investigation by the health authorities. The food additive Cu-pyropheophytin a was found in all confiscated samples in concentrations between 0.02 and 0.39 µg/g. Survey results of another 235 commercial oil samples manufactured from other companies, including olive pomace oil, extra virgin olive oil, olive oil, grapeseed oil and blended oil, indicated high positive incidences of 63%, 39%, 44%, 97% and 8%, respectively, with a concentration range between 0.02 and 0.54 µg/g. High Cu-chlorophyll concentrations are indications for fraudulent adulteration of oils.


Assuntos
Clorofilídeos/análise , Gorduras Insaturadas na Dieta/análise , Corantes de Alimentos/análise , Contaminação de Alimentos , Inspeção de Alimentos/métodos , Óleos de Plantas/química , Clorofila/análogos & derivados , Clorofila/análise , Cromatografia Líquida de Alta Pressão , Gorduras Insaturadas na Dieta/economia , Indústria de Processamento de Alimentos/economia , Frutas/química , Guias como Assunto , Resíduos Industriais/análise , Resíduos Industriais/economia , Limite de Detecção , Azeite de Oliva/química , Azeite de Oliva/economia , Azeite de Oliva/normas , Feofitinas/análise , Fotometria , Óleos de Plantas/normas , Sementes/química , Espectrofotometria Ultravioleta , Taiwan , Espectrometria de Massas em Tandem , Vitis/química
7.
Artigo em Inglês | MEDLINE | ID: mdl-25896944

RESUMO

The determination of phthalates in edible oils (virgin olive oil, olive oil, canola oil, hazelnut oil, sunflower oil, corn oil) sold in Turkish markets was carried out using gas chromatography-mass spectrometry. Mean phthalate concentrations were between 0.102 and 3.863 mg L(-1) in virgin olive oil; 0.172 and 6.486 mg L(-1) in olive oil; 0.501 and 3.651 mg L(-1) in hazelnut oil; 0.457 and 3.415 mg L(-1) in canola oil; 2.227 and 6.673 mg L(-1) in sunflower oil; and 1.585 and 6.248 mg L(-1) in corn oil. Furthermore, the influence of the types of oil and container to the phthalate migration was investigated. The highest phthalate levels were measured in sunflower oil. The lowest phthalate levels were determined in virgin olive oil and hazelnut oil. The highest phthalate levels were determined in oil samples contained in polyethylene terephthalate.


Assuntos
Gorduras Insaturadas na Dieta/análise , Disruptores Endócrinos/análise , Contaminação de Alimentos , Embalagem de Alimentos , Ácidos Ftálicos/análise , Óleos de Plantas/química , Plastificantes/análise , Óleo de Milho/efeitos adversos , Óleo de Milho/química , Óleo de Milho/economia , Corylus/química , Gorduras Insaturadas na Dieta/efeitos adversos , Gorduras Insaturadas na Dieta/economia , Disruptores Endócrinos/toxicidade , Ácidos Graxos Monoinsaturados/efeitos adversos , Ácidos Graxos Monoinsaturados/química , Ácidos Graxos Monoinsaturados/economia , Inspeção de Alimentos , Cromatografia Gasosa-Espectrometria de Massas , Humanos , Limite de Detecção , Nozes/química , Azeite de Oliva/efeitos adversos , Azeite de Oliva/química , Azeite de Oliva/economia , Azeite de Oliva/normas , Ácidos Ftálicos/toxicidade , Óleos de Plantas/efeitos adversos , Óleos de Plantas/economia , Plastificantes/toxicidade , Polietilenotereftalatos/química , Polietilenotereftalatos/toxicidade , Óleo de Brassica napus , Medição de Risco , Óleo de Girassol , Turquia
8.
Artigo em Inglês | MEDLINE | ID: mdl-25777369

RESUMO

In this study a total of 522 samples were collected from Shandong province of China in 2014 and analysed for the occurrence of fumonisin B1 (FB1), FB2 and FB3 by isotope dilution ultrahigh performance liquid chromatography-tandem mass spectrometry. Fumonisins were detected in 98.1% of the corn products, with the average total level of 369.2 µg kg(-1). The individual average values of FB1, FB2 and FB3 in corn products were 268.3, 53.7 and 47.2 µg kg(-1), respectively. The simultaneous occurrence of FB1, FB2 and FB3 was observed in 76.7% of the corn products. Especially, the results demonstrated that the difference in the contamination levels for fumonisins in these three types of corn products was apparent. In addition, 6.2% of the wheat flour samples were contaminated with FB1, with concentrations ranging from 0.3 to 34.6 µg kg(-1). No FB2 or FB3 was detected in wheat flour. In corn oil samples no fumonisins were detected.


Assuntos
Gorduras Insaturadas na Dieta/análise , Grão Comestível/química , Farinha/análise , Contaminação de Alimentos , Fumonisinas/análise , Óleos de Plantas/química , Zea mays/química , Calibragem , Carcinógenos Ambientais/análise , China , Cromatografia Líquida de Alta Pressão , Gorduras Insaturadas na Dieta/economia , Gorduras Insaturadas na Dieta/normas , Grão Comestível/economia , Grão Comestível/normas , Farinha/economia , Farinha/normas , Inspeção de Alimentos/métodos , Guias como Assunto , Limite de Detecção , Óleos de Plantas/economia , Óleos de Plantas/normas , Reprodutibilidade dos Testes , Espectrometria de Massas por Ionização por Electrospray , Espectrometria de Massas em Tandem
9.
Public Health Nutr ; 18(18): 3260-4, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25757509

RESUMO

OBJECTIVE: Long-chain n-3 fatty acid intake in Colombia is low because fish consumption is limited. Vegetable oils with high n-3 fatty acid content are recommended, but their concentrations of trans fats were high in previous studies. Thus, regular monitoring of the fatty acid composition of vegetable oils is required. Our objective was to quantify the fatty acid composition in commercially available oils in Bogota, Colombia and determine if composition changed from 2008 to 2013. DESIGN: Cross-sectional study. We obtained samples of all commercially available oils reported in a survey of low- and middle-income families with a child participating in the Bogota School Children Cohort. SETTING: Bogota, Colombia. SUBJECTS: Not applicable. RESULTS: Sunflower oil had the highest trans-fatty acid content (2.18%). Canola oil had the lowest proportion of trans-fatty acids (0.40%) and the highest n-3 fatty acid content (9.37%). In terms of percentage reduction from 2008 to 2013 in 18:1 and 18:2 trans-fatty acids, canola oil had 89% and 65% reduction, mixed oils had 44% and 48% reduction, and sunflower oil had 25% and 51 % reduction, respectively. Soyabean oil became widely available in 2013. CONCLUSIONS: The content of trans-fatty acids decreased in all oils from 2008 to 2013, suggesting a voluntary reduction by industry. We believe that regular monitoring of the fatty acid composition of oils is warranted.


Assuntos
Culinária , Gorduras Insaturadas na Dieta/análise , Fidelidade a Diretrizes , Política Nutricional , Óleos de Plantas/química , Ácidos Graxos trans/análise , População Urbana , Estudos de Coortes , Colômbia , Custos e Análise de Custo , Estudos Transversais , Inquéritos sobre Dietas , Gorduras Insaturadas na Dieta/administração & dosagem , Gorduras Insaturadas na Dieta/efeitos adversos , Gorduras Insaturadas na Dieta/economia , Família , Rotulagem de Alimentos , Indústria de Processamento de Alimentos/economia , Indústria de Processamento de Alimentos/tendências , Humanos , Renda , Óleos de Plantas/administração & dosagem , Óleos de Plantas/efeitos adversos , Óleos de Plantas/economia , Ácidos Graxos trans/administração & dosagem , Ácidos Graxos trans/efeitos adversos , Ácidos Graxos trans/economia
10.
Food Nutr Bull ; 35(4): 440-8, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25639129

RESUMO

BACKGROUND: The global economic crisis in 2007/08 resulted in higher food prices, which increased household food expenditures while worsening the quantity and quality of food consumed, potentially leading to child undernutrition. OBJECTIVE: To characterize the relationship of the mean proportions of household expenditures on strategic foods with the prevalence of undernutrition (high stunting, wasting, and underweight) among children under 2 years of age in Indonesia. METHODS: The study used data from 437 districts from two nationally representative surveys conducted in 2007, the National Socioeconomic Survey (Susenas) and the Basic Health Research (Riskesdas). RESULTS: A higher mean proportion of household expenditure on soybeans was significantly associated with lower odds (3rd vs. 1st tertile) of prevalence of high wasting (OR, 0.51; 95% CI, 0.28 to 0.94; p =.031) and high underweight (OR, 0.09; 95% CI, 0.03 to 0.28; p < .0001). A lower mean proportion of household expenditure on sugar and cooking oil was significantly associated with lower odds of prevalence of high wasting (OR, 2.41; 95% CI, 1.37 to 4.23; p = .002) and high underweight (2nd vs. 1st tertile) (OR, 2.38; 95% CI, 1.05 to 5.41; p = .039). CONCLUSIONS: Among all strategic foods, a higher proportion of household expenditure on soybeans and a lower proportion of household expenditure on sugar and cooking oil are associated with lower odds of high wasting and underweight prevalence among children 0 to 23 months of age. The results indicate the need for promotion of consumption of fermented soybeans and education aiming at decreasing expenditure on sugar and cooking oil to increase consumption of more nutritious foods.


Assuntos
Alimentos/economia , Desnutrição/epidemiologia , Orçamentos , Carboidratos/economia , Custos e Análise de Custo , Gorduras Insaturadas na Dieta/economia , Características da Família , Humanos , Indonésia/epidemiologia , Lactente , Recém-Nascido , Valor Nutritivo , Razão de Chances , Glycine max/economia , Magreza/epidemiologia
11.
Atheroscler Suppl ; 7(2): 61-2, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16716765

RESUMO

Since the start in Italy and Denmark more than 10 years ago the application of fats and oils without trans fatty acids (TFA) has increased all over the world. Today the food industry uses enormous resources to decrease the content of TFA in existing and new products. The food industry has in most cases succeeded in making consumer accepted products without TFA-most of the quality issues have been related to the technological properties of the fat- and oil-based ingredients. The change from the traditional process of selective hydrogenation to fractionation and interesterification has caused a change in the demand of vegetable oils and process capacities in the market, but until now most of these changes has been absorbed by the market without significant changes in the cost of the raw materials.


Assuntos
Gorduras Insaturadas na Dieta/economia , Indústria Alimentícia/economia , Alimentos/economia , Ácidos Graxos trans/economia , Custos e Análise de Custo , Dinamarca , Gorduras Insaturadas na Dieta/efeitos adversos , Gorduras Insaturadas na Dieta/história , Alimentos/efeitos adversos , Indústria Alimentícia/história , História do Século XX , História do Século XXI , Itália , Controle de Qualidade , Ácidos Graxos trans/efeitos adversos , Ácidos Graxos trans/história
12.
Atheroscler Suppl ; 7(2): 47-52, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16713385

RESUMO

A high intake of industrially produced trans fatty acids (IP-TFA) is associated with increased risk of coronary heart disease (CHD), and a daily intake as low as possible is required to minimize health risks. To achieve this at the individual level in Denmark, legislation limited IP-TFA in foods to a maximum of 2% of fat content from 2004. We assessed the potential exposure of consumers to IP-TFA by analysing popular foods in Denmark, and in 25 other countries. Fifty-five servings of French fries and chicken nuggets, 87 packages of microwave popcorn, and 393 samples of biscuits/cakes/wafers with "partially hydrogenated vegetable fat" listed high on the food label were bought between November 2004 and February 2006. The content of IP-TFA was analysed by standardized methodology. We defined a "high trans menu" as a large size serving of French fries and nuggets, 100 g of microwave popcorn, and 100 g of biscuits/wafers/cakes. The amounts of IP-TFA in a "high trans menu" was 30 g in 2001 in Denmark, but was reduced to less than 1g in 2005. By contrast, a "high trans menu" provided more than 20 g in 17 out of 18 countries, with Hungary, Czech Republic, Poland, Bulgaria, and USA, ranking highest with 42, 40, 38, 37, and 36 g, respectively. The legislation in Denmark has reduced the exposure of IP-TFA at the individual level without noticeable effect on availability, price, and quality of foods previously containing high amounts of IP-TFA. The findings of high concentrations of IP-TFA in popular foods outside Denmark suggest that millions of people inside and outside EU have intakes of IP-TFA that may increase their risk of CHD. The Danish experience demonstrates that this risk can be eliminated.


Assuntos
Doença das Coronárias/prevenção & controle , Gorduras Insaturadas na Dieta , Suplementos Nutricionais , Indústria Alimentícia/legislação & jurisprudência , Política Nutricional/legislação & jurisprudência , Ácidos Graxos trans , Doença das Coronárias/etiologia , Dinamarca , Gorduras Insaturadas na Dieta/efeitos adversos , Gorduras Insaturadas na Dieta/economia , Suplementos Nutricionais/efeitos adversos , Suplementos Nutricionais/economia , Indústria Alimentícia/economia , Humanos , Política Nutricional/economia , Ácidos Graxos trans/efeitos adversos , Ácidos Graxos trans/economia
13.
Atheroscler Suppl ; 7(2): 57-9, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16713387

RESUMO

With the scientific evidence associating trans fatty acid (TFA) intake with an increased risk of coronary heart disease (CHD), the U.S. Food and Drug Administration (FDA) issued a final rule that requires the declaration of the amount of TFA present in foods, including dietary supplements, on the nutrition label by January 1, 2006. The addition of TFA to the nutrition label will lead to the prevention of 600 to 1200 cases of CHD and 240-480 deaths each year saving Dollars 900 million to Dollars 1.8 billion per year in medical costs, lost productivity, and pain and suffering. For the purpose of nutrition labeling, TFA are defined as the sum of all unsaturated fatty acids that contain one or more isolated (i.e. non-conjugated) double bonds in a trans configuration. There are many issues that FDA has yet to resolve: (1) defining nutrient content claims for "free" and "reduced" levels of trans fat, (2) placing limits on the amount of TFA in conjunction with saturated fat limits for nutrient content claims, health claims, and disclosure and disqualifying levels, (3) a daily value, and (4) a possible footnote or disclosure statement to enhance consumer understanding of cholesterol raising lipids. FDA issued an Advanced Notice of Proposed Rulemaking (ANPR) requesting comments on the unresolved issues. FDA will also be conducting consumer research to determine consumer understanding of various TFA labeling possibilities. Comments to the ANPR, results of consumer research and current science will be used by FDA to resolve these issues and to determine future rulemaking for TFA labeling.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Gorduras Insaturadas na Dieta , Indústria Alimentícia/legislação & jurisprudência , Rotulagem de Alimentos/legislação & jurisprudência , Legislação sobre Alimentos , United States Food and Drug Administration/legislação & jurisprudência , Doenças Cardiovasculares/etiologia , Doenças Cardiovasculares/mortalidade , Gorduras Insaturadas na Dieta/efeitos adversos , Gorduras Insaturadas na Dieta/economia , Indústria Alimentícia/economia , Humanos , Legislação sobre Alimentos/economia , Ácidos Graxos trans/efeitos adversos , Ácidos Graxos trans/economia , Estados Unidos , United States Food and Drug Administration/economia
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