RESUMO
OBJECTIVE: To highlight the characteristics of pulmonary hyalinizing granuloma (PHG). METHOD: One patient with PHG confirmed by pathological assessment was presented and relevant literatures were reviewed. RESULTS: PHG is a rare disease characterized by multiple bilateral pulmonary nodules. Symptoms include cough, dyspnea, chest pain, hemoptysis, fever and fatigue. Histologically, the nodules consist of haphazard or whorled arrays of lamellar, keloid - like collagen. Evidence suggests that the nodules are the result of a chronic exaggerated immune response. CONCLUSIONS: PHG should be considered in patients showing multiple bilateral pulmonary nodules. The clinical course of PHG in most patients is benign. At present, there is no effective therapy.