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1.
Eur J Gastroenterol Hepatol ; 34(1): 104-111, 2022 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-33852508

RESUMO

OBJECTIVE: Diabetes is the fifth leading cause of death in the People's Republic of China. The aim of the article is to compare the effects of nursing care on the laboratory findings and ultrasound results of diabetic patients with chronic liver diseases (CLD) who were treated with antiglycemic drugs. METHODS: Diabetic were patients treated with metformin hydrochloride in combination with gliclazide, pioglitazone hydrochloride, sitagliptin, exenatide or liraglutide. Non-alcoholic fatty liver disease (NAFLD) was evaluated by abdominal ultrasound, and fibrosis stages were evaluated at baseline and 8 months. All the patients were equally divided into two groups depending on the therapeutic approach. RESULTS: The first group of patients additionally received nursing care, and the second group adhered to the prescribed therapy on their own. In total 90 patients, or 55.6%, had NAFLD at baseline, and its course was dependent upon changes in the weight (P = 0.009) and waist circumference (P = 0.012). The proportions of patients who demonstrated an ultrasonographic improvement in the control group were: 24 (56.8%) with gliclazide, 15 (41.3%) with pioglitazone hydrochloride, 28 (66.1%) with sitagliptin, 16 (79%) with exenatide and 15 (66.7%) with liraglutide (P = 0.2). For the group that received nursing care an ultrasonographic improvement was in: 29 (68.16%) with gliclazide, 18 (49.56%) with pioglitazone hydrochloride, 33 (79.32%) with sitagliptin, 19 (94.8%) with exenatide and 21 80.04% with liraglutide (P = 0.2). CONCLUSIONS: Outcomes from the type 2 diabetes treatment paralleling of CLD were presented. Treatment of type 2 diabetes with pioglitazone hydrochloride, gliclazide, sitagliptin, liraglutide and exenatide was proven effective.


Assuntos
Diabetes Mellitus Tipo 2 , Hipoglicemiantes , Hepatopatia Gordurosa não Alcoólica , Diabetes Mellitus Tipo 2/tratamento farmacológico , Diabetes Mellitus Tipo 2/enfermagem , Exenatida/efeitos adversos , Gliclazida/efeitos adversos , Humanos , Hipoglicemiantes/efeitos adversos , Liraglutida/efeitos adversos , Metformina/efeitos adversos , Hepatopatia Gordurosa não Alcoólica/diagnóstico por imagem , Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico , Hepatopatia Gordurosa não Alcoólica/enfermagem , Pioglitazona/efeitos adversos , Fosfato de Sitagliptina/efeitos adversos
2.
Nursing ; 50(3): 32-39, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32068703

RESUMO

Nonalcoholic fatty liver disease (NAFLD) is defined as storage of excess fat in the liver not caused by heavy alcohol consumption. Nonalcoholic steatohepatitis is the severe form of NAFLD. This article discusses causes, diagnosis, and nursing interventions for patients with either disorder.


Assuntos
Hepatopatia Gordurosa não Alcoólica/enfermagem , Humanos , Síndrome Metabólica , Hepatopatia Gordurosa não Alcoólica/etiologia , Avaliação em Enfermagem , Diagnóstico de Enfermagem , Educação de Pacientes como Assunto , Fatores de Risco , Índice de Gravidade de Doença
3.
Clin Gastroenterol Hepatol ; 17(10): 2132-2133, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-30448600

RESUMO

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, affecting nearly 1 in 3 Americans.1 Nonalcoholic steatohepatitis (NASH), the clinically aggressive variant of NAFLD, has a propensity of fibrosis progression and increased risk of cirrhosis and hepatocellular carcinoma. NASH-related cirrhosis is now the most rapidly growing indication for liver transplantation (LT).2 Disease recurrence and progression to advanced fibrosis after LT are high3; however, the key contributors of these are unknown. We hypothesized that patients with NASH cirrhosis reside in a microenvironment conducive to not only development of NASH but also fibrosis progression, which likely persist after LT and contribute to disease recurrence. The hypothesis was tested by performing vibration-controlled transient elastography (VCTE) in primary caregivers and cohabitants of patients with decompensated cirrhosis awaiting LT.


Assuntos
Cuidadores/estatística & dados numéricos , Cirrose Hepática/enfermagem , Fígado/diagnóstico por imagem , Hepatopatia Gordurosa não Alcoólica/epidemiologia , Filhos Adultos/estatística & dados numéricos , Idoso , Alanina Transaminase/metabolismo , Aspartato Aminotransferases/metabolismo , Diabetes Mellitus/epidemiologia , Dieta/estatística & dados numéricos , Carboidratos da Dieta , Gorduras na Dieta , Dislipidemias/epidemiologia , Técnicas de Imagem por Elasticidade , Ingestão de Energia , Ácidos Graxos , Feminino , Humanos , Hipertensão/epidemiologia , Cirrose Hepática/etiologia , Transplante de Fígado , Masculino , Pessoa de Meia-Idade , Hepatopatia Gordurosa não Alcoólica/complicações , Hepatopatia Gordurosa não Alcoólica/diagnóstico por imagem , Hepatopatia Gordurosa não Alcoólica/enfermagem , Pais , Prevalência , Índice de Gravidade de Doença , Sódio na Dieta , Cônjuges/estatística & dados numéricos
4.
Gastroenterol Nurs ; 41(5): 424-426, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30272604

RESUMO

The incidence of nonalcoholic fatty liver disease (NAFLD) has increased over the past few decades because of the obesity epidemic and is also strongly associated with diabetes Type 2. Patients often present asymptomatically until the liver disease becomes advanced. Alternatively, persons with NAFLD can present with various stages of inflammation, hepatosis, or fibrosis, which can eventually result in cirrhosis and lead to hepatocellular carcinoma. Lifestyle modifications are the most important aspects of cirrhosis prevention. These changes are crucial because cirrhosis is a known cause of long-term liver disease. Nurse practitioners play an important role in the early detection of NAFLD and prevention of its potentially life-threatening complications.


Assuntos
Estilo de Vida Saudável , Hepatopatia Gordurosa não Alcoólica/diagnóstico , Hepatopatia Gordurosa não Alcoólica/enfermagem , Profissionais de Enfermagem , Papel do Profissional de Enfermagem , Educação de Pacientes como Assunto/métodos , Carcinoma Hepatocelular/etiologia , Carcinoma Hepatocelular/prevenção & controle , Gerenciamento Clínico , Progressão da Doença , Feminino , Humanos , Cirrose Hepática/etiologia , Cirrose Hepática/prevenção & controle , Neoplasias Hepáticas/etiologia , Neoplasias Hepáticas/prevenção & controle , Masculino , Hepatopatia Gordurosa não Alcoólica/complicações , Prognóstico , Medição de Risco , Resultado do Tratamento
7.
Nurse Pract ; 42(7): 14-20, 2017 07 15.
Artigo em Inglês | MEDLINE | ID: mdl-28562448

RESUMO

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease in the United States and will soon be the leading indication for liver transplantation. NAFLD can lead to cirrhosis of the liver and is usually asymptomatic. Prompt referral to a hepatologist may halt the morbidity and mortality associated with NAFLD.


Assuntos
Hepatopatia Gordurosa não Alcoólica/epidemiologia , Humanos , Incidência , Hepatopatia Gordurosa não Alcoólica/enfermagem , Hepatopatia Gordurosa não Alcoólica/fisiopatologia , Diagnóstico de Enfermagem , Estados Unidos/epidemiologia
8.
Nurs Stand ; 30(52): 15, 2016 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-27641564

RESUMO

Essential facts Non-alcoholic fatty liver disease (NAFLD) is an excess of fat in the liver that is not the result of excessive alcohol consumption or other secondary causes, such as hepatitis C. According to the National Institute for Health and Care Excellence, fatty liver - steatosis - affects between 20% and 30% of the population and its prevalence is increasing.


Assuntos
Hepatopatia Gordurosa não Alcoólica/diagnóstico , Hepatopatia Gordurosa não Alcoólica/terapia , Humanos , Hepatopatia Gordurosa não Alcoólica/enfermagem , Hepatopatia Gordurosa não Alcoólica/fisiopatologia , Relações Enfermeiro-Paciente , Fatores de Risco
9.
Nurs N Z ; 22(11): 20-24, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30556967

RESUMO

IMPAIRED LIVER function affects every aspect of the body's physiology. Diseases of the liver have more widespread and life-threatening impacts than malfunctioning of any of the body's other conditions. accessory organs. Non-alcoholic fatty Liver disease rates are soaring, concurrent with the obesity epidemic and increasing rates of type 2 diabetes. Alcoholic liver disease and viral hepatitis also contribute to high rates of liver damage in the population, making liver disease one of the commonest causes premature death. Liver transplants, hepatocellular carcinomas, and deaths from Liver disease are increasingly due to preventable or treatable liver conditions. Understanding normal liver function allows nurses to predict the impact of Liver disease on their patients' health and well-being. Knowledge of underlying causes of impaired liver function enhances our ability to support and counsel those who are at risk of, or have been diagnosed with liver disease.


Assuntos
Hepatopatias/enfermagem , Fígado/fisiologia , Carcinoma Hepatocelular/metabolismo , Carcinoma Hepatocelular/enfermagem , Carcinoma Hepatocelular/fisiopatologia , Hepatite Viral Humana/metabolismo , Hepatite Viral Humana/enfermagem , Hepatite Viral Humana/fisiopatologia , Humanos , Fígado/citologia , Fígado/metabolismo , Hepatopatias/metabolismo , Hepatopatias/fisiopatologia , Hepatopatias Alcoólicas/metabolismo , Hepatopatias Alcoólicas/enfermagem , Hepatopatias Alcoólicas/fisiopatologia , Testes de Função Hepática , Neoplasias Hepáticas/metabolismo , Neoplasias Hepáticas/enfermagem , Neoplasias Hepáticas/fisiopatologia , Transplante de Fígado/enfermagem , Hepatopatia Gordurosa não Alcoólica/metabolismo , Hepatopatia Gordurosa não Alcoólica/enfermagem , Hepatopatia Gordurosa não Alcoólica/fisiopatologia
10.
Nurse Pract ; 40(11): 36-42; quiz 42-3, 2015 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-26474202

RESUMO

Nonalcoholic fatty liver disease (NAFLD) is becoming a worldwide health crisis. It is important for NPs to understand the spectrum of NAFLD. Although lifestyle modifications are the first-line treatment, the NP should be aware of current and future medication management to help the patient live a healthy life.


Assuntos
Hepatopatia Gordurosa não Alcoólica/enfermagem , Profissionais de Enfermagem , Guias de Prática Clínica como Assunto , Competência Clínica , Humanos , Estilo de Vida , Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico , Hepatopatia Gordurosa não Alcoólica/epidemiologia , Hepatopatia Gordurosa não Alcoólica/fisiopatologia , Diagnóstico de Enfermagem , Fatores de Risco
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