RESUMO
We report a case of laboratory-acquired meningococcal disease in a 31-y-old female research assistant. The clinical presentation of the case was atypical with polyserositis affecting knees, pleura and pericardium, without septicaemia or meningitis. The diagnosis was made by positive PCR for Neisseria meningitidis (genogroup C, genosubtype P1.7, 16, 35 and without mutations of the penA gene) in the patient's right knee. Serology confirmed the diagnosis after recovery. This case had an atypical clinical picture, exemplifies the use of non-culture methods for diagnosis and characterization, and reminds us about the importance of safe routines for the laboratory work.
Assuntos
Infecção Laboratorial , Pessoal de Laboratório Médico , Infecções Meningocócicas , Neisseria meningitidis Sorogrupo C/isolamento & purificação , Serosite , Adulto , Feminino , Humanos , Articulação do Joelho/microbiologia , Infecção Laboratorial/diagnóstico , Infecção Laboratorial/microbiologia , Infecção Laboratorial/fisiopatologia , Infecções Meningocócicas/diagnóstico , Infecções Meningocócicas/microbiologia , Infecções Meningocócicas/fisiopatologia , Neisseria meningitidis Sorogrupo C/classificação , Neisseria meningitidis Sorogrupo C/genética , Serosite/diagnóstico , Serosite/microbiologia , Serosite/fisiopatologiaRESUMO
This case report should remind physicians that toxoplasmosis may cause serious illness in healthy adults. Difficulties in the differential diagnosis of the disease are discussed.
