RESUMO
The history of the management of craniopharyngiomas offers a comprehensive review of the exciting progress in neurosurgery, neuroimaging, neuroendocrinology and radiation oncology during the last century. In this historical note, we present the evolution in management of these most challenging of brain tumours, which, despite the substantial knowledge and expertise gained since the first attempt of surgical removal, remains a subject of considerable debate.
Assuntos
Craniofaringioma/história , Neoplasias Hipofisárias/história , Craniofaringioma/terapia , História do Século XX , Humanos , Procedimentos Neurocirúrgicos/história , Irradiação Hipofisária/história , Neoplasias Hipofisárias/cirurgiaRESUMO
Craniopharyngiomas, although histologically benign, are usually so intimately associated with the hypothalamus that total extirpation of these tumors was generally followed by death from hypotension and gross endocrine deficiencies. During the first half of the present century, those recording their tribulations include the famous names of Grant, Bailey, Bucy, Peet, Kahn, Olivecrona, Norlen, Sjöqvist, Rougerie and Northfield. Matson and Sweet were the first to achieve major reductions in mortality by giving massive doses of cortisone plus meticulous dissection, which took advantage of the reactive glial envelope which surrounds the great majority of these tumors.
Assuntos
Craniofaringioma/história , Hipofisectomia/história , Irradiação Hipofisária/história , Neoplasias Hipofisárias/história , Criança , Europa (Continente) , História do Século XX , Humanos , Estados UnidosRESUMO
Yttrium implantation is one of the many ways of treating acromegaly. The advantages are the minor nature of the procedure and the fact that pituitary replacement is not as commonly required as after hypophysectomy. Thus in young female patients menstruation may be resumed following treatment and pregnancy has occurred. The procedure is not as free from complications as external irradiation but the response is more satisfactory.
