Terminología anatómica internacional del mediastino / International anatomical terminology of the mediastinum

Introducción: La evolución y crecimiento de la anatomía comociencia hicieron que adquiera un lenguaje técnico propiodestinado a facilitar la comunicación entre profesionales de lasalud alrededor del mundo evitando el uso de distintas denominaciones para un mismo objeto. Objetivos: Remarcar la importancia del conocimiento y lautilización de la TAI de la región del mediastino por el cirujano general, en el contexto de la globalización de la información medica. Material y métodos: Durante el periodo Junio/2013-Enero/2014,se realizó una encuesta anónima a 86 médicos especialistas en Cirugía General. Se tuvieron en cuenta: los años de graduado yde especialista, el conocimiento de la terminología anatómica y laactualización bibliográfica y la identificación de estructuras anatómicas en cortes esquemáticos...

Introduction: The evolution and growth of anatomy as a sciencemade it acquires its own technical language to facilitate communication between health professionals around the world avoiding the use of different names for the same object. Objectives: To emphasize the importance of knowledge and theuse of TAI of the region of the mediastinum by the generalsurgeon, in the context of the globalization of health information. Material and methods: During the June/2013-January/2014period we performed an anonymous survey of 86 medicalspecialists in General Surgery. The following items were taken intoaccount: the years of graduate and specialist, the level of knowledge of the anatomical terminology and literature review and identification of anatomical structures in schematic cuts...

Cystic lesions of the mediastinum.

Cysts of the mediastinum comprise a relatively diverse group of lesions that include neoplastic and nonneoplastic constituents, the latter of which are largely congenital in nature. Therefore, a grasp of their clinicopathologic characteristics is bolstered by knowledge of which tumors in the chest may undergo cystic change, as well as the embryologic development of the thoracic organs. That information, as well as radiological and pathologic features of these lesions, is discussed in this review.

Comparative morphologic and immunohistochemical investigation of spontaneously occurring thymomas in a colony of European hamsters.

This study documents the characteristics of a large series of spontaneously occurring thymomas in a laboratory colony of European hamsters (Cricetus cricetus). Thymomas are rare organotypic neoplasms originating from the thymic epithelial compartment. Because the hamster thymomas largely resembled their human counterparts, the recent World Health Organization (WHO) classification of human thymic epithelial tumors was used. Forty hamsters of both sexes aged 3-29 months were examined macroscopically and histologically. In 22 (55%) of the 40 animals, necropsy revealed enormous whitish masses in the anterior mediastinum, with a diameter ranging from 0.5 to 4.5 cm and a lobulated structure. The anatomy of the thymus region was normal in the remaining 18 hamsters. Histologically, the tumors presented as thymuslike organoid structures with areas of medullary and cortical differentiation and a predominance of lymphoid cells. A network of epithelial cells in the cortical areas, demonstrated immunohistochemically with a cross-reactive antibody against pancytokeratin, supported the diagnosis of thymoma. Cortical lymphocytes showed positive staining with cross-reacting antibodies against CD3 and terminal deoxynucleotidyl transferase, characteristic of immature T cells. On the basis of these findings, the tumors were classified as B1 thymomas, in some cases with AB or B2 components, according to the new WHO classification for human thymic epithelial tumors.

[Histogenesis of the immune system of the "nude" mouse. II. Postnatal development of the thymus: a light microscopical study (author's transl)]. / Histogenese des Immunsystems der "nude" Maus. II. Postnatale Entwicklung des Thymus: eine lichtmikroskopische Studie

UNLABELLED: The thymus of the homozygous nude mouse embryo is laid down normally. From the 13th day post conceptionem (pc) onwards, however, a maldevelopment takes place (Groscurth und Kistler, 1974). As a result, the anterior mediastinum of the newborn nu/nu mouse contains a rudimentary epithelial organ which resembles parts of an embryonic exocrine gland. In this paper, the light microscopical findings of the postnatal development of the thymus in homo- and heterozygous nude mice are reported. MATERIAL AND METHODS: Homo- and heterozygous nude (nu/nu and nu/+) mice with the genetic background BALB/c were kept under specific pathogen-free (spf) conditions. Three nu/nu and three nu/+ female mice were sacrificed at the following developmental stages: newborn animal, 1st, 2nd, 3rd, 6th, 9th as well as 12th week postpartum (pp). The organs were fixed in Bouin's solution and embedded in paraffin wax. Serial sections (5 mu) were stained with hematoxylin and eosin. RESULTS AND DISCUSSION: The bilobed thymus rudiment of the newborn nu/nu mouse consists of branching ducts. From the 2nd week post partum (pp) onwards, their epithelial cells proliferate. At the same time, some of these cells begin to differentiate into serous and mucous cells. In some parts of the rudiment, they also form thyroid-like follicles. The exocrine cells secrete their products into the lumina of the ducts. As there is no connection between the thymus rudiment and either the epidermis or the digestive tract, an accumulation of secretory products takes place, resulting in a dilatation of the whole duct system. Therefore, the thymus rudiment of the 12-week-old nu/nu mouse consists of a number of communicating cysts which are lined by a flattened epithelium. Cysts lined by an epithelium can also be observed within the thymus of the nu/+ mouse. Two types must be distinguished..