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1.
Artigo em Inglês | MEDLINE | ID: mdl-33396598

RESUMO

In order to curb increasing youth electronic cigarette (e-cig) use, the United States Food and Drug Administration (FDA) banned the sale of flavored cartridge/pod-based products in February 2020. This mixed-methods study aimed to evaluate the impact of the FDA ban on adult JUUL users. The samples of current adult JUUL users were surveyed via Amazon Mechanical Turk at three time-points n = 76 (Sample 1); n = 128 (Sample 2); n = 86 (Sample 3) before and after the FDA flavored/pod ban. The participants were asked to report the JUUL flavored pod used most often and answer questions on purchasing generic pods or refilling (Quantitative). JUUL users were then interviewed in order to explore their perceptions and behaviors related to the FDA ban of flavored cartridge/pod-based products (Qualitative; n = 16). Quantitative data analysis evaluated the differences in variables by time-point. Qualitative data were coded into themes while using the constant comparative method. We found a significant decrease in the use of mint pods (43.4%, 22.7%, 16.3%) (p < 0.01), while there was a significant increase in the use of menthol pods (6.6%, 26.6%, 37.2%) (p < 0.01). Themes that emerged from the qualitative data included switching from mint to menthol pods, refilling pods, and switching to other products that are available in the desired flavors, such as generic pods or disposable e-cigs. Future research is needed in order to evaluate the impact of these behaviors on public health.


Assuntos
Sistemas Eletrônicos de Liberação de Nicotina , Aromatizantes , Nicotina , Vaping , Adolescente , Adulto , Idoso , Sistemas Eletrônicos de Liberação de Nicotina/estatística & dados numéricos , Feminino , Aromatizantes/provisão & distribuição , Humanos , Masculino , Pessoa de Meia-Idade , Nicotina/provisão & distribuição , Estados Unidos , Vaping/legislação & jurisprudência , Vaping/psicologia , Adulto Jovem
4.
Int J Environ Res Public Health ; 8(5): 1547-59, 2011 05.
Artigo em Inglês | MEDLINE | ID: mdl-21655136

RESUMO

Many tobacco cessation quitlines provide nicotine replacement therapy (NRT) in the U.S. but consensus is lacking regarding the best shipping protocol or NRT amounts. We evaluated the impact of the Minnesota QUITPLAN(®) Helpline's shift from distributing NRT using a single eight-week shipment to a two-shipment protocol. For this observational study, the eight week single-shipment cohort (n = 247) received eight weeks of NRT (patches or gum) at once, while the split-shipment cohort (n = 160) received five weeks of NRT (n = 94), followed by an additional three weeks of NRT if callers continued with counseling (n = 66). Patient satisfaction, retention, quit rates, and cost associated with the three groups were compared. A higher proportion of those receiving eight weeks of NRT, whether in one or two shipments, reported that the helpline was "very helpful" (77.2% of the single-shipment group; 81.1% of the two-shipment group) than those receiving five weeks of NRT (57.8% of the one-shipment group) (p = 0.004). Callers in the eight week two-shipment group completed significantly more calls (3.0) than callers in the five week one-shipment group (2.4) or eight week single-shipment group (1.7) (p < 0.001). Using both responder and intent-to-treat calculations, there were no significant differences in 30-day point prevalence abstinence at seven months among the three protocol groups even when controlling for demographic and tobacco use characteristics, and treatment group protocol. The mean cost per caller was greater for the single-shipment phase than the split-shipment phase ($350 vs. $326) due to the savings associated with not sending a second shipment to some participants. Assuming no difference in abstinence rates resulting from the protocol change, cost-per-quit was lowest for the five week one-shipment group ($1,155), and lower for the combined split-shipment cohort ($1,242) than for the single-shipment cohort ($1,350). Results of this evaluation indicate that while satisfaction rates increase among those receiving more counseling and NRT, quit rates do not, even when controlling for demographic and tobacco use characteristics.


Assuntos
Nicotina/provisão & distribuição , Agonistas Nicotínicos/provisão & distribuição , Abandono do Hábito de Fumar/economia , Tabagismo/tratamento farmacológico , Adolescente , Adulto , Análise Custo-Benefício , Feminino , Linhas Diretas/estatística & dados numéricos , Humanos , Masculino , Nicotina/administração & dosagem , Agonistas Nicotínicos/administração & dosagem , Satisfação do Paciente , Avaliação de Programas e Projetos de Saúde , Abandono do Hábito de Fumar/estatística & dados numéricos , Resultado do Tratamento , Adulto Jovem
5.
Prev Med ; 50(5-6): 288-96, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20144648

RESUMO

OBJECTIVE: Since 2003, the New York City Department of Health and Mental Hygiene has distributed nicotine replacement therapy nicotine replacement therapy to adult smokers through annual large-scale distribution programs. METHODS: In 2008, the New York City Department of Health and Mental Hygiene formally integrated geographic information system analyses to track program enrollment, map the geographic density of enrollees, and assess the effects of outreach strategies. RESULTS: Geographic information system analyses provided a unique, near real-time visual method of assessing participation patterns as well as the impact of media and outreach strategies. Among neighborhoods with high smoking prevalence, lower income neighborhoods had higher enrollment compared to higher income neighborhoods. Mapping before and after a press release demonstrated that program interest increased over 700% in one area. CONCLUSION: Although geographic information system analysis is traditionally utilized for large-scale infectious disease surveillance, the New York City Department of Health and Mental Hygiene used GIS to inform and improve an annual large-scale smoking cessation program. These analyses provide unique feedback that can aid public health program planners in improving efficiency and efficacy of service delivery.


Assuntos
Sistemas de Informação Geográfica/estatística & dados numéricos , Nicotina/provisão & distribuição , Agonistas Nicotínicos/provisão & distribuição , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Abandono do Hábito de Fumar/estatística & dados numéricos , Fumar , Adolescente , Adulto , Idoso , Planejamento em Saúde Comunitária , Relações Comunidade-Instituição , Uso de Medicamentos/estatística & dados numéricos , Feminino , Pesquisa sobre Serviços de Saúde/métodos , Humanos , Internet/organização & administração , Masculino , Meios de Comunicação de Massa , Pessoa de Meia-Idade , Cidade de Nova Iorque/epidemiologia , Nicotina/uso terapêutico , Agonistas Nicotínicos/uso terapêutico , Vigilância da População , Prevalência , Avaliação de Programas e Projetos de Saúde/métodos , Prática de Saúde Pública , Fumar/epidemiologia , Abandono do Hábito de Fumar/métodos , Prevenção do Hábito de Fumar , Serviços Urbanos de Saúde/organização & administração
8.
Nicotine Tob Res ; 10(12): 1789-92, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19023830

RESUMO

This study used over-the-counter (OTC) sales of nicotine replacement therapy (NRT) to investigate the impact of the introduction of smoke-free legislation in Scotland in March 2006 on smoking cessation behaviour. The time series of NRT sales (units and value) in Scotland from 2004 to 2006 were compared with the same period for the rest of the UK, and analysed using an ARIMA time series model. There was a significant increase in units and value of NRT sales in Scotland in the first 6 months of 2006 (p< or =0.001), apparent from January and prior to the introduction of the smoking ban, with no comparable increase for the rest of the UK. There was no significant increase in NRT sales for the second half of 2006. These data suggest an increase in smoking cessation behaviour in the period immediately before the introduction of smoke-free legislation, but this was not sustained beyond the first few months of the post-legislation period.


Assuntos
Promoção da Saúde/legislação & jurisprudência , Nicotina/provisão & distribuição , Medicamentos sem Prescrição/provisão & distribuição , Abandono do Hábito de Fumar/métodos , Fumar/tratamento farmacológico , Tabagismo/tratamento farmacológico , Comportamentos Relacionados com a Saúde , Política de Saúde , Humanos , Nicotina/administração & dosagem , Medicamentos sem Prescrição/administração & dosagem , Escócia , Abandono do Hábito de Fumar/legislação & jurisprudência , Prevenção do Hábito de Fumar , Indústria do Tabaco/legislação & jurisprudência , Tabagismo/prevenção & controle
10.
Nicotine Tob Res ; 7(4): 547-55, 2005 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16085526

RESUMO

In 1996, the FDA approved over-the-counter (OTC) availability of nicotine gum and two brands of nicotine skin patches. Little is known about how this reclassification has influenced the effectiveness and use of nicotine replacement therapy (NRT) and whether it has been a public health benefit. Data for the present study came from a prospective cohort study of 1,639 adult smokers surveyed by telephone in 1993, as part of the National Cancer Institute's Community Intervention Trial for Smoking Cessation (COMMIT), and resurveyed in 2001. NRT-assisted quit rates, NRT use rates, and the characteristics of NRT users were calculated before and after the 1996 OTC reclassification. Also calculated was the percentage of NRT users who quit by year. Results are presented for patch and gum separately and combined. OTC NRT use rates were lower for Hispanics and higher for those with no desire to quit at baseline. The quit rate decreased for patch-assisted quit attempts after OTC reclassification (22.5% to 18.5%, p = .05), but it did not change for gum-assisted quit attempts (11.9% to 10.5%, p = .54). NRT use rates increased for both patch and gum by about 60% following reclassification. A greater percentage of gum users had quit in the post-OTC period than in the pre-OTC period (9.7% vs. 14.6%, p = .05). Long-term quit rates in patch users were similar in both periods. Insurance coverage of NRT and concurrent attendance in a stop smoking clinic decreased for both patch- and gum-assisted attempts in the post-OTC period. The results suggest that OTC reclassification may have contributed to the increased use of NRT, compared with the pre-OTC period, whereas the efficacy for quitting decreased slightly for those using nicotine patch and remained about the same for those using the gum.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Promoção da Saúde/estatística & dados numéricos , Nicotina/uso terapêutico , Medicamentos sem Prescrição/provisão & distribuição , Abandono do Hábito de Fumar/estatística & dados numéricos , Fumar/tratamento farmacológico , Adulto , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nicotina/provisão & distribuição , Medicamentos sem Prescrição/uso terapêutico , Estudos Prospectivos , Abandono do Hábito de Fumar/métodos , Prevenção do Hábito de Fumar , Inquéritos e Questionários , Fatores de Tempo , Estados Unidos
11.
Psychopharmacology (Berl) ; 182(4): 516-26, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16075286

RESUMO

RATIONALE: There is evidence that prefrontal lobe GABA levels are low in cocaine-dependent (CD) individuals, and treatment with GABA agonists decreases cocaine self-administration. OBJECTIVES: The aim of the study is to measure changes in GABA levels in CD subjects at baseline and after 8 weeks of treatment with pramipexole, venlafaxine, or placebo. METHODS: CD subjects enrolled in a treatment trial for cocaine dependence were recruited for this proton (1H) magnetic resonance spectroscopy (MRS) study. GABA levels in the prefrontal lobe were measured before and after treatment. RESULTS: Mean percentage changes in GABA levels were as follows: pramipexole +17.0+/-28.0%, venlafaxine +13.0+/-11.0%, and placebo -2.1+/-19.5%. Pramipexole-treated subjects had significantly increased brain GABA levels compared to placebo (p=0.031). Venlafaxine treatment was nonsignificantly associated with increased GABA levels compared to placebo (p=0.16). The overall statistical model for the effect of drug treatment vs placebo on brain GABA levels, including adjustment for baseline levels, was highly significant (p=0.002). Despite significant changes in GABA levels, there were no significant differences in the number of urine samples positive for cocaine metabolites. CONCLUSIONS: This study demonstrates that 1H MRS can measure changes in GABA levels following pharmacologic treatment. The increase in GABA levels, although significant, is modest compared to other MRS studies of depression or epilepsy associated with clinical improvements. The failure to see larger increases in GABA levels and an associated reduction in cocaine consumption may reflect the relatively low doses of medication used.


Assuntos
Antidepressivos de Segunda Geração/uso terapêutico , Transtornos Relacionados ao Uso de Cocaína/tratamento farmacológico , Córtex Pré-Frontal/efeitos dos fármacos , Ácido gama-Aminobutírico/metabolismo , Adulto , Antioxidantes/uso terapêutico , Benzotiazóis , Cicloexanóis/uso terapêutico , Método Duplo-Cego , Feminino , Humanos , Espectroscopia de Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Nicotina/provisão & distribuição , Pramipexol , Prótons , Estudos Retrospectivos , Tiazóis/uso terapêutico , Fatores de Tempo , Cloridrato de Venlafaxina
12.
Am J Public Health ; 95(6): 1050-5, 2005 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15914832

RESUMO

OBJECTIVES: Recently, New York City and New York State increased cigarette excise taxes and New York City implemented a smoke-free workplace law. To assess the impact of these policies on smoking cessation in New York City, we examined over-the-counter sales of nicotine replacement therapy (NRT) products. METHODS: Pharmacy sales data were collected in real time as part of nontraditional surveillance activities. We used Poisson generalized estimating equations to analyze the effect of smoking-related policies on pharmacy-specific weekly sales of nicotine patches and gum. We assessed effect modification by pharmacy location. RESULTS: We observed increases in NRT product sales during the weeks of the cigarette tax increases and the smoke-free workplace law. Pharmacies in low-income areas generally had larger and more persistent increases in response to tax increases than those in higher-income areas. CONCLUSIONS: Real-time monitoring of existing nontraditional surveillance data, such as pharmacy sales of NRT products, can help assess the effects of public policies on cessation attempts. Cigarette tax increases and smoke-free workplace regulations were associated with increased smoking cessation attempts in New York City, particularly in low-income areas.


Assuntos
Nicotina/provisão & distribuição , Farmácias/estatística & dados numéricos , Política Pública , Abandono do Hábito de Fumar/estatística & dados numéricos , Fumar/tratamento farmacológico , Tabagismo/tratamento farmacológico , Promoção da Saúde/legislação & jurisprudência , Humanos , Cidade de Nova Iorque/epidemiologia , Nicotina/administração & dosagem , Distribuição de Poisson , Fumar/epidemiologia , Fumar/legislação & jurisprudência , Impostos/legislação & jurisprudência , Indústria do Tabaco/legislação & jurisprudência , Tabagismo/epidemiologia , Tabagismo/prevenção & controle , População Urbana , Local de Trabalho/legislação & jurisprudência
13.
Annu Rev Public Health ; 26: 583-99, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15760302

RESUMO

This review summarizes evidence pertaining to the role of nicotine medications in smoking cessation and focuses particularly on evaluating evidence of the impact that nicotine replacement therapies (NRT) have had on altering population trends in smoking behavior. Accumulated evidence from controlled clinical trials has demonstrated that available forms of NRT (e.g., gum, transdermal patch, nasal spray, inhaler, and lozenge) increase quit rates compared with placebos by 50%-100%. However, despite the positive results from these studies, fewer than one in five smokers making a quit attempt do so with the benefit of NRT. Because not enough smokers are using NRT, the availability of NRT has not had a measurable impact on influencing population trends in smoking behavior. Among the factors contributing to the low utilization of nicotine medications are the inadequacies of the current dosage strengths and formulations of existing medications, smokers' perceptions of the high cost of the drugs, and concerns that many smokers have about safety and efficacy of nicotine medications.


Assuntos
Nicotina/uso terapêutico , Agonistas Nicotínicos/uso terapêutico , Abandono do Hábito de Fumar/métodos , Prevenção do Hábito de Fumar , Química Farmacêutica , Planejamento em Saúde Comunitária , Aprovação de Drogas , Custos de Medicamentos , Uso de Medicamentos/economia , Uso de Medicamentos/estatística & dados numéricos , Medicina Baseada em Evidências , Humanos , Licenciamento em Farmácia , Nicotina/química , Nicotina/economia , Nicotina/provisão & distribuição , Agonistas Nicotínicos/química , Agonistas Nicotínicos/economia , Agonistas Nicotínicos/provisão & distribuição , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Saúde Pública/métodos , Segurança , Fumar/psicologia , Abandono do Hábito de Fumar/economia , Abandono do Hábito de Fumar/psicologia , Resultado do Tratamento , Estados Unidos , United States Food and Drug Administration
14.
Am J Manag Care ; 11(2): 77-85, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15726855

RESUMO

OBJECTIVES: To evaluate the effectiveness of the Veterans Health Administration (VHA) in providing treatment for tobacco dependence, accomplished by estimating national trends in the number and percent of smokers receiving smoking cessation aids (SCAs) within the VHA, trends in SCA utilization and expenditures, and the impact of lifting restrictions on patient access to SCAs. STUDY DESIGN AND METHODS: All patients receiving an outpatient SCA prescription were identified within the Veterans Affairs (VA) Pharmacy Benefits Management database over a 4-year period- October 1, 1998 (n = 61 968) to September 30, 2002 (n = 76 641). Smoking prevalence was based on data from the VA's 1999 Large Health Survey of Enrollees. A subsample of sites was classified as having restricted access to SCAs if patients were required to attend smoking cessation classes. Changes in annual SCA utilization rates and expenditures by SCA type and restriction status were measured to assess changes in treatment of tobacco dependence. RESULTS: Approximately 7% of smokers received SCA prescriptions, and SCAs accounted for less than 1% of the VHA's annual outpatient pharmacy budget in any given year. Following downward trends in the cost of 30-day SCA prescriptions, annual SCA expenditures per patient decreased over time. Expenditures were lower for restricted than unrestricted sites. More than two thirds of smokers who were prescribed medications received the nicotine patch, a quarter received bupropion sustained-release, and fewer than 10% received nicotine gum. CONCLUSIONS: Measures of SCA utilization and cost are low, stable, and less than the recommended rates in national smoking cessation guidelines, suggesting that this population of smokers is undertreated. Removing SCA restrictions is not prohibitively expensive and improves access to cost-effective care.


Assuntos
Bupropiona/administração & dosagem , Revisão de Uso de Medicamentos , Hospitais de Veteranos/normas , Nicotina/administração & dosagem , Abandono do Hábito de Fumar/estatística & dados numéricos , Prevenção do Hábito de Fumar , Fumar/tratamento farmacológico , Veteranos/psicologia , Adulto , Idoso , Bupropiona/economia , Bupropiona/provisão & distribuição , Goma de Mascar , Bases de Dados como Assunto , Humanos , Pessoa de Meia-Idade , Nicotina/economia , Nicotina/provisão & distribuição , Serviço de Farmácia Hospitalar/economia , Fumar/epidemiologia , Abandono do Hábito de Fumar/economia , Abandono do Hábito de Fumar/métodos , Estados Unidos/epidemiologia , United States Department of Veterans Affairs
16.
Rev. esp. geriatr. gerontol. (Ed. impr.) ; 36(supl.1): 36-44, mar. 2001. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-150867

RESUMO

Los fumadores de 50 años o más son un grupo de pacientes vulnerables, con riesgo de enfermedades complicadas por el hecho de fumar. Pueden obtener beneficios significativos en su salud si abandonan este hábito, aunque probablemente llevan fumando muchos años y sufren una gran adicción. El médico es una pieza fundamental para conseguir que dejen el tabaco. Los médicos pueden mejorar significativamente la salud de sus fumadores ancianos con un plan o intervención mínima de cinco pasos: identificar sistemáticamente a todos los fumadores en cada visita, aconsejar firmemente dejar de fumar, identificar a aquellos fumadores que quieren hacer un intento de cesación, prestar la ayuda y el soporte necesario, realizar seguimiento. Se exponen las diferentes terapias farmacológicas (AU)


Smokers 50 years old or more are a damaged group of patients, with the risk of having complicated illness because of tobacco. If they finish smoking, they can obtain significant benefits in their health, although they smoke many years ago and have a great addition. The doctor is an important element for finishing smoking. Doctors can improve the old smokers health significantly with a five-steps plan: to identify in a systematic way all smokers in each visit, to advise seriously leaving smoking, to identify the smokers who want leaving smoking seriously, to give necessary help, and to do pursuit. The different pharmacologic therapies are exposed (AU)


Assuntos
Humanos , Masculino , Feminino , Idoso , Fumar/efeitos adversos , Fumar/metabolismo , Terapêutica/métodos , Preparações Farmacêuticas/administração & dosagem , Nicotina/administração & dosagem , Qualidade de Vida , Pessoal de Saúde/educação , Pessoal de Saúde/ética , Fumar/prevenção & controle , Fumar/psicologia , Terapêutica/psicologia , Preparações Farmacêuticas/metabolismo , Nicotina/provisão & distribuição , Qualidade de Vida/psicologia , Pessoal de Saúde/psicologia , Pessoal de Saúde/normas
20.
Can J Cardiovasc Nurs ; 4(2): 20-3, 1993.
Artigo em Inglês | MEDLINE | ID: mdl-8148066

RESUMO

Despite repeated health warnings, cigarette smoking continues to cause significant morbidity and mortality to society. This may be attributal in large, to the addictive properties of nicotine and the withdrawal symptoms following smoking cessation. A clearer understanding of nicotine addiction has introduced new approaches to its treatment. This article will review the symptoms and treatment of nicotine addiction and withdrawal, with a particular focus on the role of the nicotine transdermal systems.


Assuntos
Nicotina/uso terapêutico , Abandono do Hábito de Fumar/métodos , Transtornos Relacionados ao Uso de Substâncias/tratamento farmacológico , Administração Cutânea , Interações Medicamentosas , Humanos , Nicotina/provisão & distribuição , Educação de Pacientes como Assunto , Transtornos Relacionados ao Uso de Substâncias/enfermagem
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