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1.
Biodemography Soc Biol ; 65(2): 172-187, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32432936

RESUMO

Persons with high temporal discounting tend to value immediate gratification over future gains. Low self-reported lifespan (SRL)-an individual's assessment of a relatively short future lifespan-concentrates in low-income populations and may reflect high temporal discounting. We use casino-based cash dividends among the Eastern Band of Cherokee Indians (EBCI) as a quasi-experiment to test whether large income gains among EBCI members translate into increased SRL. We used SRL data for EBCI and White youth, aged 19 to 28, participating in two waves of the Life Time Trajectory of Youth (LTI-Y) survey from 2000 to 2010. We controlled for unobserved confounding across individuals, time, and region through a longitudinal design using a difference-in-difference analytic approach (N = 294). We conducted all analyses separately by gender and by quartile of socioeconomic status. Cash dividends correspond with a 15.23 year increase in SRL among EBCI men below the lowest socio-economic quartile at baseline relative to Whites (standard error = 5.39, p < .01). Results using other socio-economic cut-points support improved SRL among EBCI men (but not women). The large magnitude of this result among EBCI men indicates that a non-trivial cash dividend to a low-income population may confer long-term benefits on perceptions of future lifespan and, in turn, reduce temporal discounting.Abbreviations: EBCI: Eastern Band of Cherokee Indians; SES: Socioeconomic Status; LTI-Y: Life Trajectory Interview for Youth; GSMS: Great Smoky Mountains Study; SRL: Self-Reported Lifespan; SSS: Subjective Social Status.


Assuntos
Renda/estatística & dados numéricos , Indígenas Sul-Americanos/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Humanos , Indígenas Sul-Americanos/etnologia , Longevidade , Masculino , Pessoa de Meia-Idade , North Carolina/etnologia , Classe Social , Inquéritos e Questionários , Análise de Sobrevida
2.
Res Nurs Health ; 43(3): 218-229, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32274808

RESUMO

In this cross-sectional study of 60 American Indian mother-child dyads from Southeastern North Carolina, we examined whether childhood asthma control was related to household-level factors, such as environmental tobacco smoke and family management behaviors. We also examined the relationships among family management behaviors and maternal depressive symptoms. We used logistic regression to assess the relationships among childhood asthma control, the presence of environmental tobacco smoke, and family management behaviors, specifically condition management ability (CMA) and condition management effort (CME). We used linear regression to evaluate the relationships between both CMA and CME and maternal depressive symptoms. Better asthma control in children was associated with the absence of environmental tobacco smoke in the home and the maternal perception of asthma as a manageable condition. Mothers perceived an increase in effort to manage their child's asthma as their depressive symptoms increased. These findings emphasize the importance of environmental triggers, perceptions of condition management, and maternal mental health in controlling asthma in American Indian children. Interventions to reduce environmental triggers, treat maternal depressive symptoms, and support mothers in their ability to manage childhood asthma may yield better asthma control and help to reduce existing racial disparities in this population.


Assuntos
Asma/prevenção & controle , Depressão/psicologia , Gerenciamento Clínico , Mães/psicologia , Poluição por Fumaça de Tabaco/efeitos adversos , Adulto , Criança , Saúde da Criança/etnologia , Pré-Escolar , Estudos Transversais , Características da Família/etnologia , Feminino , Humanos , Masculino , North Carolina/epidemiologia , North Carolina/etnologia , Fatores Socioeconômicos , Indígena Americano ou Nativo do Alasca/etnologia
3.
Matern Child Health J ; 23(10): 1382-1391, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31273497

RESUMO

OBJECTIVES: We examine the association between several dimensions of parental socioeconomic status (SES) and all-cause and cause-specific mortality among children and youth (ages 1-24) in the United States. METHODS: We use Cox proportional hazard models to estimate all-cause and cause-specific mortality risk based on data from the 1998 to 2015 National Health Interview Survey-Linked Mortality Files (NHIS-LMFs), restricted to children and youth ages 1-17 at the time of survey followed through age 24, or the end of the follow-up period in 2015 (N = 377,252). RESULTS: Children and youth in families with lower levels of mother's education, father's education, and/or family income-to-needs ratio exhibit significantly higher all-cause mortality risk compared with children and youth living in higher SES families. For example, compared to children and youth living with mothers who earned college degrees, those living with mothers who have not graduated high school experience 40% higher risk of early life mortality over the follow-up period, due in part to higher mortality risks of unintentional injuries and homicides. Similarly, children/youth whose fathers did not graduate high school experience a 41% higher risk of dying before age 25 compared to those with fathers who completed college. CONCLUSIONS: Today's children and youth experience clear disparities in mortality risk across several dimensions of parental SES. As the U.S. continues to lag behind other high-income countries in health and mortality, more attention and resources should be devoted to improving children's health and well-being, including the family and household contexts in which American children live.


Assuntos
Mortalidade/tendências , Medição de Risco/métodos , Classe Social , Adolescente , Criança , Pré-Escolar , Características da Família/etnologia , Feminino , Humanos , Lactente , Masculino , Mortalidade/etnologia , North Carolina/etnologia , Modelos de Riscos Proporcionais , Medição de Risco/etnologia , Medição de Risco/estatística & dados numéricos , Fatores de Risco , Inquéritos e Questionários , Adulto Jovem
4.
BMC Public Health ; 18(1): 982, 2018 08 06.
Artigo em Inglês | MEDLINE | ID: mdl-30081868

RESUMO

BACKGROUND: Disparities in the prevalence of HIV persist in the southern United States, and young African American women have a disproportionate burden of HIV as compared with young women of other racial/ethnic backgrounds. As a result, engaging young African American women in the HIV care continuum through HIV testing is imperative. This study is designed to reach this key population at risk for HIV. The study seeks to test the efficacy of two formats of a gender-focused, evidence-based, HIV-risk reduction intervention-the Young Women's CoOp (YWC)-relative to HIV counseling and testing (HCT) among young African American women between the ages of 18 and 25 who use substances and have not recently been tested for HIV. METHODS: Using a seek-and-test framework, this three-arm cross-over randomized trial is being conducted in three county health departments in North Carolina. Each county is assigned to one of three study arms in each cycle: in-person (face-to-face) YWC, mobile Health (mHealth) YWC, or HCT. At study enrollment, participants complete a risk behavior survey via audio computer-assisted self-interview, and drug, alcohol, and pregnancy screening tests, and are then referred to HIV, gonorrhea, and chlamydia testing through their respective health departments. Participants in either of the YWC arms are asked to return approximately 1 week later to either begin the first of two in-person individual intervention sessions or to pick up the mHealth intervention preloaded on a tablet after a brief introduction to using the app. Participants in all arms are asked to return for a 6-month follow-up and 12-month follow-up, and repeat the survey and biological testing from baseline. DISCUSSION: The findings from this study will demonstrate which delivery format (mHealth or face-to-face) is efficacious in reducing substance use and sexual risk behaviors. If found to be efficacious, the intervention has potential for wider dissemination and reach. TRIAL REGISTRATION: ClinicalTrials.gov: NCT02965014 . Registered November 16, 2016.


Assuntos
Negro ou Afro-Americano , Aconselhamento/métodos , Infecções por HIV/prevenção & controle , Promoção da Saúde/métodos , Assunção de Riscos , Comportamento Sexual , Telemedicina/métodos , Adolescente , Adulto , Feminino , Infecções por HIV/diagnóstico , Infecções por HIV/etnologia , Humanos , Programas de Rastreamento , North Carolina/etnologia , Gravidez , Testes de Gravidez , Projetos de Pesquisa , Infecções Sexualmente Transmissíveis , Transtornos Relacionados ao Uso de Substâncias/diagnóstico , Transtornos Relacionados ao Uso de Substâncias/etnologia , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Saúde da Mulher , Adulto Jovem
5.
JAMA Netw Open ; 1(5): e182716, 2018 09 07.
Artigo em Inglês | MEDLINE | ID: mdl-30646172

RESUMO

Importance: Data from electronic health records (EHRs) are increasingly used for risk prediction. However, EHRs do not reliably collect sociodemographic and neighborhood information, which has been shown to be associated with health. The added contribution of neighborhood socioeconomic status (nSES) in predicting health events is unknown and may help inform population-level risk reduction strategies. Objective: To quantify the association of nSES with adverse outcomes and the value of nSES in predicting the risk of adverse outcomes in EHR-based risk models. Design, Setting, and Participants: Cohort study in which data from 90 097 patients 18 years or older in the Duke University Health System and Lincoln Community Health Center EHR from January 1, 2009, to December 31, 2015, with at least 1 health care encounter and residence in Durham County, North Carolina, in the year prior to the index date were linked with census tract data to quantify the association between nSES and the risk of adverse outcomes. Machine learning methods were used to develop risk models and determine how adding nSES to EHR data affects risk prediction. Neighborhood socioeconomic status was defined using the Agency for Healthcare Research and Quality SES index, a weighted measure of multiple indicators of neighborhood deprivation. Main Outcomes and Measures: Outcomes included use of health care services (emergency department and inpatient and outpatient encounters) and hospitalizations due to accidents, asthma, influenza, myocardial infarction, and stroke. Results: Among the 90 097 patients in the training set of the study (57 507 women and 32 590 men; mean [SD] age, 47.2 [17.7] years) and the 122 812 patients in the testing set of the study (75 517 women and 47 295 men; mean [SD] age, 46.2 [17.9] years), those living in neighborhoods with lower nSES had a shorter time to use of emergency department services and inpatient encounters, as well as a shorter time to hospitalizations due to accidents, asthma, influenza, myocardial infarction, and stroke. The predictive value of nSES varied by outcome of interest (C statistic ranged from 0.50 to 0.63). When added to EHR variables, nSES did not improve predictive performance for any health outcome. Conclusions and Relevance: Social determinants of health, including nSES, are associated with the health of a patient. However, the results of this study suggest that information on nSES may not contribute much more to risk prediction above and beyond what is already provided by EHR data. Although this result does not mean that integrating social determinants of health into the EHR has no benefit, researchers may be able to use EHR data alone for population risk assessment.


Assuntos
Registros Eletrônicos de Saúde/estatística & dados numéricos , Disparidades nos Níveis de Saúde , Características de Residência/estatística & dados numéricos , Classe Social , Adulto , Idoso , Estudos de Coortes , Feminino , Humanos , Renda/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , North Carolina/etnologia , Avaliação de Resultados em Cuidados de Saúde/métodos , Avaliação de Resultados em Cuidados de Saúde/estatística & dados numéricos , Grupos Raciais/etnologia , Grupos Raciais/estatística & dados numéricos , Determinantes Sociais da Saúde/etnologia , Determinantes Sociais da Saúde/estatística & dados numéricos
6.
Palliat Support Care ; 16(6): 662-668, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29229011

RESUMO

OBJECTIVE: Among African Americans, spirituality is meaning or purpose in life and a faith in God who is in control of health and there to provide support and guidance in illness situations. Using qualitative methods, we explored the use of spirituality to make sense of the end-of-life and bereavement experiences among family members of a deceased cancer patient. METHOD: Data in this report come from 19 African Americans who experienced the loss of a family member to cancer. A qualitative descriptive design was used with criterion sampling, open-ended semistructured interviews, and qualitative content analysis. RESULTS: Participants made sense of the death of their loved one using the following five themes: Ready for life after death; I was there; I live to honor their memory; God's wisdom is infinite; and God prepares you and brings you through. These five themes are grounded in conceptualizations of spirituality as connectedness to God, self, and others.Significance of resultsOur findings support the results that even during bereavement, spirituality is important in the lives of African Americans. African American family members might struggle with issues related to life after death, their ability to be physically present during end-of-life care, and disentangling beliefs around God's control over the beginning and ending of life. The findings in this report can be used to inform healthcare providers to better support and address the needs for support of African American family members during end-of-life and bereavement experiences.


Assuntos
Atitude Frente a Morte/etnologia , Negro ou Afro-Americano/psicologia , Neoplasias/psicologia , Espiritualidade , Adulto , Negro ou Afro-Americano/etnologia , Idoso , Família/etnologia , Família/psicologia , Feminino , Humanos , Entrevistas como Assunto/métodos , Masculino , Pessoa de Meia-Idade , Neoplasias/complicações , Neoplasias/mortalidade , North Carolina/etnologia , Pesquisa Qualitativa
7.
Cancer Causes Control ; 28(9): 929-938, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28695396

RESUMO

PURPOSE: To examine racial differences in smoking rates at the time of breast cancer diagnosis and subsequent survival among African American and non-African American women in the Carolina Breast Cancer Study (Phases I/II), a large population-based North Carolina study. METHODS: We interviewed 788 African American and 1,020 Caucasian/non-African American women diagnosed with invasive breast cancer from 1993 to 2000, to assess smoking history. After a median follow-up of 13.56 years, we identified 717 deaths using the National Death Index; 427 were breast cancer-related. We used Cox regression to examine associations between self-reported measures of smoking and breast cancer-specific survival within 5 years and up to 18 years after diagnosis conditional on 5-year survival. We examined race and estrogen receptor status as potential modifiers. RESULTS: Current (vs never) smoking was not associated with 5-year survival; however, risk of 13 year conditional breast cancer-specific mortality was elevated among women who were current smokers at diagnosis (HR 1.54, 95% CI 1.06-2.25), compared to never smokers. Although smoking rates were similar among African American (22.0%) and non-African American (22.1%) women, risk of breast cancer-specific mortality was elevated among African American (HR 1.69, 95% CI 1.00-2.85), but only weakly elevated among non-African American (HR 1.22, 95% CI 0.70-2.14) current (vs. never) smokers (P Interaction = 0.30). Risk of breast cancer-specific mortality was also elevated among current (vs never) smokers diagnosed with ER- (HR 2.58, 95% CI 1.35-4.93), but not ER+ (HR 1.11, 95% CI 0.69-1.78) tumors (P Interaction = 0.17). CONCLUSIONS: Smoking may negatively impact long-term survival following breast cancer. Racial differences in long-term survival, as related to smoking, may be driven by ER status, rather than by differences in smoking patterns.


Assuntos
Neoplasias da Mama/epidemiologia , Receptores de Estrogênio/metabolismo , Fumar/epidemiologia , Adulto , Negro ou Afro-Americano/estatística & dados numéricos , Idoso , Neoplasias da Mama/etnologia , Neoplasias da Mama/metabolismo , Feminino , Humanos , Pessoa de Meia-Idade , North Carolina/epidemiologia , North Carolina/etnologia , Risco , Fumar/etnologia , Estados Unidos , População Branca/estatística & dados numéricos , Adulto Jovem
8.
J Agromedicine ; 22(3): 275-281, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28409702

RESUMO

OBJECTIVE: Providing health program information to vulnerable communities, such as Latino farmworkers, is difficult. This analysis describes the manner in which farmworkers receive information about the Affordable Care Act, comparing farmworkers with other Latinos. METHODS: Interviews were conducted with 100 Latino farmworkers and 100 urban Latino North Carolina residents in 2015. RESULTS: Most farmworkers had received health information from a community organization. Trusted sources for health information were health care providers and community organizations. Sources that would influence decisions to enroll were Latino nurses and doctors, religious leaders, and family members. Traditional media, including oral presentation and printed material at the doctor's office, were preferred by the majority of farmworkers and non-farmworkers. Farmworkers used traditional electronic media: radio, television, and telephone. More non-farmworkers used current electronic media: e-mail and Internet. CONCLUSIONS: Latino farmworkers and non-farmworkers prefer traditional media in the context of a health care setting. They are willing to try contemporary electronic media for this information.


Assuntos
Hispânico ou Latino/psicologia , Patient Protection and Affordable Care Act/estatística & dados numéricos , Acesso à Informação , Adulto , Idoso , Atitude Frente a Saúde , Fazendeiros/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , North Carolina/etnologia , Projetos Piloto , Migrantes/psicologia , Adulto Jovem
9.
Breast Cancer Res Treat ; 162(2): 375-388, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-28155053

RESUMO

PURPOSE: Obesity and weight gain after breast cancer (BC) diagnosis can affect cancer outcomes. This study explores the question of weight change during the first 2 years of endocrine treatment (ET) to identify the independent effects of BC diagnosis and treatment on post-diagnosis weight trajectories in early-stage postmenopausal BC survivors. METHODS: The study design is a retrospective chart review. Chi square tests and ANOVA were used to compare patients who gained >2 kg, lost >2 kg, or had stable weight. Log-binomial regression models were used to evaluate associations between patient characteristics and weight trajectories. RESULTS: The final sample is N = 300, with mean age at BC diagnosis of 65 years and 76% white. After 2 years of ET, 39% of study participants had gained >2 kg, 27% had lost >2 kg, and 34% had stable weight. Relative risks (RR) for weight gain were as follows: age at diagnosis = 0.98 (0.96, 0.99), being married = 1.48 (1.04, 2.12), weight change between BC diagnosis and start of ET = 0.98 (0.97, 0.99), Stage II = 1.42 (1.01, 2.01) or Stage III = 1.99 (1.41, 2.82), PR negative = 0.70 (0.51, 0.96), HER2 positive = 1.51 (1.07, 2.13), mastectomy = 1.49 (1.12, 1.98), axillary node dissection = 1.67 (1.27, 2.20), adjuvant chemotherapy = 1.49 (1.02, 2.19), and neoadjuvant chemotherapy = 2.29 (1.67, 3.14). Type of ET (tamoxifen or aromatase inhibitor) was not significant. CONCLUSIONS: In our sample of postmenopausal early-stage BC survivors, a majority had stable or lost weight during the first 2 years of ET. Higher disease complexity and associated treatment posed higher RR for weight gain.


Assuntos
Peso Corporal , Neoplasias da Mama/epidemiologia , Pós-Menopausa , Adulto , Idoso , Idoso de 80 Anos ou mais , Antineoplásicos Hormonais/uso terapêutico , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/tratamento farmacológico , Sobreviventes de Câncer , Quimioterapia Adjuvante , Comorbidade , Feminino , Humanos , Pessoa de Meia-Idade , Metástase Neoplásica , Estadiamento de Neoplasias , North Carolina/epidemiologia , North Carolina/etnologia , Estudos Retrospectivos , Medição de Risco , Fatores de Tempo
10.
J Am Acad Child Adolesc Psychiatry ; 56(2): 124-132.e2, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28117058

RESUMO

OBJECTIVE: Recent changes in DSM criteria require new documentation of the prevalence and developmental sequences of cannabis use disorder (CUD). The goal of this study was to investigate the early course of DSM-5 CUD and its overlap with DSM-IV and consumption constructs in a community-representative sample of American Indians. METHOD: Data came from the prospective, longitudinal, population-based Great Smoky Mountains Study in North Carolina (N = 1,420, including 349 American Indians). Cannabis use and disorder were assessed during yearly interviews from 9 to 16 years of age and at 19, 21, 26, and 30 years of age (up to 11 assessments per participant from 1993 through 2015). RESULTS: By 30 years of age, approximately 70% of participants had used cannabis, 34% had used cannabis daily, and 18% had met criteria for DSM-5 CUD. Approximately 1 in 4 cannabis users met criteria for CUD at some point. Those who met criteria initiated use more than 2 years previously (at 13.3 years old) compared with other users. Despite higher risks from increased poverty, American Indians' patterns of use were similar to those of the rest of the sample. Concordance between DSM-5 CUD and DSM-IV abuse or dependence was substantial but was even higher between DSM-5 CUD and daily use. CONCLUSION: It was common to have used cannabis daily or to have met criteria for DSM-5 CUD by adulthood. DSM-5 CUD was an improvement over DSM-IV diagnostic constructs by raising the threshold for diagnosis.


Assuntos
Indígenas Norte-Americanos/etnologia , Abuso de Maconha/etnologia , Uso da Maconha/etnologia , Adolescente , Adulto , Criança , Manual Diagnóstico e Estatístico de Transtornos Mentais , Feminino , Humanos , Estudos Longitudinais , Masculino , Abuso de Maconha/diagnóstico , North Carolina/etnologia , Adulto Jovem
11.
World Neurosurg ; 97: 431-437, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27751919

RESUMO

OBJECTIVE: To examine the influence of race, gender, and socioeconomic factors on presentations and outcomes of adult Chiari I malformations. METHODS: The charts of 638 adult patients with Chiari I malformations were reviewed, and 287 patients were included in the study. Race, gender, insurance status, symptoms, depth of cerebellar tonsillar herniation, and presence of syringomyelia were examined as covariates in multivariate logistic regression models to identify independent predictors of presentation and outcome. RESULTS: Patients with public insurance had a longer stay in the hospital (P = 0.01). A higher proportion of male patients presented with upper extremity weakness (P = 0.01), lower extremity weakness (P = 0.040), and cranial nerve findings (P = 0.02). Men had shorter onset to diagnosis times (P = 0.02), worse tonsillar herniation (P = 0.03), and more severe symptoms (P = 0.05). White patients more frequently presented with back pain (P = 0.03), and African American patients more frequently presented with lower extremity weakness (P = 0.01). African Americans had worse tonsillar herniation (P < 0.01) and were more likely to present with syringomyelia (P = 0.01). Multivariate regression analysis revealed that back pain (P < 0.01), upper extremity weakness (P ≤ 0.01), upper extremity paresthesias (P < 0.01), and upper with lower extremity paresthesias (P = 0.04) were significant predictors of syringomyelia. The only independent predictor of outcome was size of tonsillar herniation (P = 0.03). CONCLUSIONS: Significant differences in presentation of Chiari I malformation resulting from gender, race, and insurance status were quantified for the first time.


Assuntos
Malformação de Arnold-Chiari/etnologia , Malformação de Arnold-Chiari/terapia , Negro ou Afro-Americano/estatística & dados numéricos , Disparidades em Assistência à Saúde/etnologia , Cobertura do Seguro/estatística & dados numéricos , Racismo/estatística & dados numéricos , População Branca/estatística & dados numéricos , Adolescente , Adulto , Negro ou Afro-Americano/etnologia , Idoso , Idoso de 80 Anos ou mais , Malformação de Arnold-Chiari/diagnóstico por imagem , Alocação de Recursos para a Atenção à Saúde/estatística & dados numéricos , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Disparidades em Assistência à Saúde/estatística & dados numéricos , Humanos , Pessoa de Meia-Idade , North Carolina/etnologia , Racismo/etnologia , Fatores de Risco , Distribuição por Sexo , Sexismo , Fatores Socioeconômicos , Resultado do Tratamento , População Branca/etnologia , Adulto Jovem
12.
Breast Cancer Res Treat ; 159(3): 535-43, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27585477

RESUMO

PURPOSE: Although racial disparities in health-related quality of life (HRQOL) among women with breast cancer (BC) are well documented, less is known about HRQOL changes over time among women of different races. Our objective was to assess racial differences in HRQOL during active treatment and survivorship phases of BC care. METHODS: We used data from the third phase of the Carolina Breast Cancer Study (CBCS-III). CBCS-III enrolled 3000 women in North Carolina aged 20-74 years diagnosed with BC between 2008 and 2013. HRQOL assessments occurred 5 and 25 months post diagnosis, representing distinct phases of care. HRQOL measures included the Functional Assessment of Cancer Therapy for BC and Functional Assessment of Chronic Illness Therapy for Spiritual Well-Being. Analysis of covariance models were employed to assess racial differences in changes in HRQOL. RESULTS: The cohort included 2142 Non-Hispanic White (n = 1105) and Black women (n = 1037) who completed both HRQOL assessments. During active treatment, Whites reported physical and functional scores 2-2.5 points higher than Blacks (p < 0.0001). Spiritual HRQOL was 2.1 points higher for Blacks (p < 0.0001). During survivorship, differences persisted. After adjusting for demographic, socioeconomic, tumor, and treatment characteristics, physical and functional HRQOL gaps narrowed, but spiritual HRQOL gaps widened. CONCLUSIONS: Racial differences in physical and functional HRQOL during active treatment and survivorship may be largely mediated by socioeconomic factors. However, our results suggest that among Black women, spiritual HRQOL is well supported throughout the BC care continuum. These results inform opportunities for improving the quality and equity of supportive services for women with BC.


Assuntos
Neoplasias da Mama/etnologia , Sobreviventes de Câncer/psicologia , Qualidade de Vida/psicologia , Adulto , Negro ou Afro-Americano/psicologia , Neoplasias da Mama/psicologia , Estudos de Coortes , Feminino , Humanos , Pessoa de Meia-Idade , North Carolina/etnologia , População Branca/psicologia , Adulto Jovem
13.
Breast Cancer Res ; 18(1): 79, 2016 08 04.
Artigo em Inglês | MEDLINE | ID: mdl-27492244

RESUMO

BACKGROUND: Young-onset breast cancer (<40 years) is associated with worse prognosis and higher mortality. Breast cancer risk factors may contribute to distinct tumor biology and distinct age at onset, but understanding of these relationships has been hampered by limited representation of young women in epidemiologic studies and may be confounded by menopausal status. METHODS: We examined tumor characteristics and epidemiologic risk factors associated with premenopausal women's and young women's breast cancer in phases I-III of the Carolina Breast Cancer Study (5309 cases, 2022 control subjects). Unconditional logistic regression was used to assess heterogeneity by age (<40 vs. ≥40 years) and menopausal status. RESULTS: In both premenopausal and postmenopausal strata, younger women had more aggressive disease, including higher stage, hormone receptor-negative, disease as well as increased frequency of basal-like subtypes, lymph node positivity, and larger tumors. Higher waist-to-hip ratio was associated with reduced breast cancer risk among young women but with elevated risk among older women. Parity was associated with increased risk among young women and reduced risk among older women, while breastfeeding was more strongly protective for young women. Longer time since last birth was protective for older women but not for young women. In comparison, when we stratified by age, menopausal status was not associated with distinct risk factor or tumor characteristic profiles, except for progesterone receptor status, which was more commonly positive among premenopausal women. CONCLUSIONS: Age is a key predictor of breast cancer biologic and etiologic heterogeneity and may be a stronger determinant of heterogeneity than menopausal status. Young women's breast cancer appears to be etiologically and biologically distinct from that among older women.


Assuntos
Neoplasias da Mama/epidemiologia , Neoplasias da Mama/etiologia , Menopausa , Adulto , Fatores Etários , Neoplasias da Mama/patologia , Estudos de Casos e Controles , Feminino , Humanos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , North Carolina/epidemiologia , North Carolina/etnologia , Paridade , Vigilância da População , Gravidez , Fatores de Risco
15.
J Am Assoc Nurse Pract ; 28(9): 479-86, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26990616

RESUMO

PURPOSE: Personal perceptions and beliefs are one of the least studied patient factors influencing medication adherence. This study explored adherence experiences of rural African Americans with type 2 diabetes in rural southeastern North Carolina. METHODS: Social-ecological theory guided a mixed methods approach. The Morisky Medication Adherence Scale (MMAS) assessed adherence. Clinical variables (HgA1c, fasting glucose levels, current medications) were obtained from medical records. Pearson correlation coefficients examined associations between demographics, clinical variables, and MMAS scores. Narrative data obtained from open-ended questions were analyzed through content analysis. RESULTS: The study enrolled 45 rural residents with longstanding type 2 diabetes (11 years, 31% on insulin). The majority of MMAS scores (63%) reflected low adherence (<6); 30% averaged moderate adherence (6 to <8). Males had poor metabolic control (HgA1c 9.0); female glycemic control was moderately good (7.2). Adherence was associated with having health insurance (r = .594, p = .001) and working for pay (r = .440, p = .05). Participants frequently underused medications without consulting a provider; financial limitations served as a major barrier. Perceptions that diabetes only occurs when "sugar is high" are inconsistent with the course of this chronic disease. CONCLUSIONS: High levels of nonadherence remain a major challenge for nursing care providers in economically distressed rural counties.


Assuntos
Negro ou Afro-Americano/psicologia , Diabetes Mellitus Tipo 2/tratamento farmacológico , Conhecimentos, Atitudes e Prática em Saúde , Adesão à Medicação/psicologia , População Rural , Adulto , Idoso , Estudos Transversais , Diabetes Mellitus Tipo 2/psicologia , Feminino , Humanos , Masculino , Adesão à Medicação/etnologia , Pessoa de Meia-Idade , North Carolina/etnologia
16.
Breast Cancer Res Treat ; 153(1): 191-200, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26216535

RESUMO

It is unknown whether racial differences exist in adjuvant chemotherapy initiation among women with similar oncotype DX (ODX) risk scores. We examined whether adjuvant chemotherapy initiation varied by race. Data come from the Phase III, Carolina Breast Cancer Study, a longitudinal, population-based study of North Carolina women diagnosed with breast cancer between 2008 and 2014. We used modified Poisson regression and report adjusted relative risk (aRR) and 95% confidence intervals (95%CI) to estimate the association between race and adjuvant chemotherapy initiation across ODX risk groups among women who received the test (n = 541). Among women who underwent ODX testing, 54.2, 37.5, and 8.3% of women had tumors classified as low-, intermediate-, and high-risk groups, respectively. We observed no racial variation in adjuvant chemotherapy initiation. Increasing ODX risk score (aRR = 1.39, 95%CI = 1.22, 1.58) and being married (aRR = 2.92, 95%CI = 1.12, 7.60) were independently associated with an increased likelihood of adjuvant chemotherapy in the low-risk group. Among women in the intermediate-risk group, ODX risk score (aRR = 1.15, 95%CI = 1.11, 1.20), younger age (aRR = 1.95, 95%CI = 1.35, 2.81), larger tumor size (aRR = 1.70, 95%CI = 1.22, 2.35), and higher income were independently associated with increased likelihood of adjuvant chemotherapy initiation. No racial differences were found in adjuvant chemotherapy initiation among women receiving ODX testing. As treatment decision-making becomes increasingly targeted with the use of genetic technologies, these results provide evidence that test results may drive treatment in a similar way across racial subgroups.


Assuntos
Neoplasias da Mama/epidemiologia , Grupos Raciais/estatística & dados numéricos , Idoso , Biomarcadores Tumorais , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/tratamento farmacológico , Quimioterapia Adjuvante , Terapia Combinada , Comorbidade , Feminino , Perfilação da Expressão Gênica/métodos , Humanos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , North Carolina/epidemiologia , North Carolina/etnologia , Sistema de Registros , Fatores de Risco , Carga Tumoral
17.
J Fam Psychol ; 29(3): 405-415, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26053349

RESUMO

African American youth, particularly those from single-mother homes, are overrepresented in statistics on externalizing problems. The family is a central context in which to understand externalizing problems; however, reliance on variable-oriented approaches to the study of parenting, which originate from work with intact, middle-income, European American families, may obscure important information regarding variability in parenting styles among African American single mothers, and in turn, variability in youth outcomes as well. The current study demonstrated that within African American single-mother families: (a) a person-, rather than variable-, oriented approach to measuring parenting style may further elucidate variability; (b) socioeconomic status may provide 1 context within which to understanding variability in parenting style; and (c) 1 marker of socioeconomic status, income, and parenting style may each explain variability in youth externalizing problems; however, the interaction between income and parenting style was not significant. Findings have potential implications for better understanding the specific contexts in which externalizing problems may be most likely to occur within this at-risk and underserved group.


Assuntos
Negro ou Afro-Americano/etnologia , Transtornos do Comportamento Infantil/etnologia , Mães/psicologia , Poder Familiar/etnologia , Família Monoparental/etnologia , Classe Social , Adolescente , Adulto , Criança , Feminino , Humanos , Renda , Masculino , Pessoa de Meia-Idade , North Carolina/etnologia
18.
Diabetes Educ ; 41(3): 291-300, 2015 06.
Artigo em Inglês | MEDLINE | ID: mdl-25722064

RESUMO

PURPOSE: The purpose of this study was to explore how emotional support emerged in interactions between peer supporters (PSs) and adults living with type 2 diabetes. METHODS: Qualitative data were analyzed from 22 semistructured interviews with PSs in 3 settings: low-income Latinos in Chicago, middle-class Caucasians in the United Kingdom, and low-income African American women in North Carolina. Emotional support was defined as expressions of empathy, trust, and caring. RESULTS: Across all sites, emotional support gradually emerged over time, was often combined with informational support, and was conveyed both implicitly (through nonverbal actions connoting emotional acceptance; eg, a walk together without discussion of problems) and explicitly (eg, by reassurance or discussion of stressors). Cross-site differences did appear regarding the strategies to address barriers to diabetes management (eg, PSs in North Carolina and Chicago reported providing support for social stressors) and the role of PSs (eg, PSs in Chicago reported providing directive support). CONCLUSIONS: Across different settings and populations, emotional support for diabetes management evolved over time, was often integrated with informational support, and emerged through both implicit and explicit strategies that addressed varied context-specific stressors.


Assuntos
Comparação Transcultural , Diabetes Mellitus Tipo 2/psicologia , Emoções , Autocuidado/psicologia , Apoio Social , Adulto , Negro ou Afro-Americano/psicologia , Chicago/etnologia , Feminino , Hispânico ou Latino/psicologia , Humanos , Masculino , Pessoa de Meia-Idade , North Carolina/etnologia , Grupo Associado , Pesquisa Qualitativa , Fatores Socioeconômicos , Fatores de Tempo , Reino Unido/etnologia , População Branca/psicologia
19.
J Gerontol B Psychol Sci Soc Sci ; 70(4): 545-56, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25098527

RESUMO

OBJECTIVES: To evaluate the effects of vascular conditions and education quality on cognition over time in White and African American (AA) older adults. METHOD: We investigated cross-sectional and longitudinal racial differences in executive functioning (EF) and memory composites among Whites (n = 461) and AAs (n = 118) enrolled in a cohort study. We examined whether cerebrovascular risk factors and Shipley Vocabulary scores (a proxy for education quality) accounted for racial differences. RESULTS: On average, AAs had lower quality of education and more cerebrovascular risk factors including hypertension, diabetes, and obesity. AAs had lower mean EF and memory at baseline, but there were no group differences in rates of decline. Cross-sectional racial differences in EF and memory persisted after controlling for vascular disease, but disappeared when controlling for Shipley Vocabulary. DISCUSSION: Quality of education appears to be more important than cerebrovascular risk factors in explaining cross-sectional differences in memory and EF performance between White and AA older adults. Further investigation is needed regarding the relative contribution of education quality and cerebrovascular risk factors to cognitive decline among ethnically/racially diverse older adults.


Assuntos
Negro ou Afro-Americano/etnologia , Transtornos Cerebrovasculares/etnologia , Vocabulário , População Branca/etnologia , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Escolaridade , Função Executiva/fisiologia , Feminino , Humanos , Estudos Longitudinais , Masculino , Memória/fisiologia , Pessoa de Meia-Idade , North Carolina/etnologia , Fatores de Risco
20.
J Appl Gerontol ; 34(5): 552-72, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24652893

RESUMO

This article describes the types of complementary therapies used by older adults for health promotion, and delineates the predisposing, enabling, and need factors associated with their use. One-hundred ninety-five African American and White participants (age 65+) completed a baseline interview and up to six sets of three daily follow-up interviews at monthly intervals. Complementary therapies for health promotion included home remedies, specific foods or beverages, herbs, supplements, vitamins, over-the-counter (OTC) medicine, prayer, exercise, and being active. Although gender, ethnicity, education, and trust in doctors were associated with the use of complementary therapies for health promotion, health information seeking was the predisposing factor most often associated. The enabling factors were also associated with their use. Health information seeking, which reflects a wellness lifestyle, had the most consistent associations with complementary therapy use for health promotion. This health self-management for health promotion may have positive effects on future medical expenditures.


Assuntos
Terapias Complementares , Promoção da Saúde/tendências , Aceitação pelo Paciente de Cuidados de Saúde/etnologia , Negro ou Afro-Americano , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Modelos Logísticos , Masculino , Análise Multivariada , Medicamentos sem Prescrição , North Carolina/etnologia , Autocuidado , População Urbana , População Branca
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