1.
FEBS Lett
; 153(1): 161-4, 1983 Mar 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6219005
RESUMO
The production of equilin and the other ring B-unsaturated estrogens by the pregnant mare is anomalous in that they are biosynthesised by a cholesterol-independent pathway. Fetal horse gonads were incubated with tritiated sodium acetate and radiochemically pure 3 beta-hydroxy-5,7-pregnadien-20-one and 3 beta-hydroxy-5,7-androstadien-17-one were isolated. A fetal gonad--placental system is proposed for equilin production, 3 beta-hydroxy-5,7-pregnadien-20-one being a precursor for 3 beta-hydroxy-5,7-androstadien-17-one in the fetal gonad and the latter being the precursor of equilin in the placenta. The nature of the possible precursor of 3 beta-hydroxy-5,7-pregnadien-20-one is discussed.
Assuntos
Gônadas/metabolismo , Cavalos/embriologia , Pregnadienos/biossíntese , Animais , Desidroepiandrosterona/metabolismo , Equilina/biossíntese , Gônadas/embriologia , Técnicas In Vitro , Pregnenolona/metabolismo
2.
Z Allg Mikrobiol
; 21(4): 289-93, 1981.
Artigo
em Alemão
| MEDLINE
| ID: mdl-7197433
3.
FEBS Lett
; 91(1): 140-3, 1978 Jul 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-668904
4.
Steroids
; 23(3): 411-20, 1974 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4828062