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1.
Neurol Res ; 33(3): 232-9, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21513643

RESUMO

OBJECTIVE: The pathogeneses of Chiari malformation type I and syringomyelia are incompletely understood. In this article, the authors attempt to review the current theories on the pathogeneses of Chiari I malformation and syringomyelia. METHODS: A literature review for articles pertaining to Chiari I malformation or syringomyelia before August 2010 was conducted; in addition, the author's own experience in treating Chiari I malformation and syringomyelia is included. RESULTS: Chiari I malformation has been defined radiographically as cerebellar tonsillar herniation or ectopia 5 mm or greater below the foramen magnum. By this narrow definition, Chiari I malformation (i.e. cerebellar tonsillar herniation or ectopia 5 mm or greater below the foramen magnum) likely encompasses a heterogeneous grouping of disorders caused by different mechanisms. Molecular and genetic studies have been helpful in furthering our understanding of Chiari I malformation. CONCLUSION: A review of the pathogeneses of Chiari I malformation and syringomyelia is reported.


Assuntos
Síndrome de Chiari-Frommel/etiologia , Síndrome de Chiari-Frommel/patologia , Siringomielia/etiologia , Siringomielia/patologia , Encéfalo/patologia , Síndrome de Chiari-Frommel/genética , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Siringomielia/genética
8.
J Reprod Med ; 14(4): 145-51, 1975 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-1142350

RESUMO

A case of postpartum amenorrhea and galactorrhea is reported, with several additional features leading to the diagnosis of primary hypothyroidism. Resolution of the amenorrhea and galactorrhea was noted coincident with adequate thyroid hormone therapy. The interrelationships of the many organ systems involved are discussed, and speculations advanced regarding the mechanisms operating in such cases. The diagnosis of the limited thyroid-reserve syndrome is elucidated.


Assuntos
Síndrome de Chiari-Frommel/etiologia , Hipotireoidismo/complicações , Adulto , Bradicardia/etiologia , Feminino , Teste de Tolerância a Glucose , Humanos , Hidrocortisona/uso terapêutico , Hipertensão/etiologia , Hipotireoidismo/diagnóstico , Hipotireoidismo/tratamento farmacológico , Gravidez , Testes de Função Tireóidea , Hormônios Tireóideos/uso terapêutico , Tireotropina/análise
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