RESUMO
An elderly woman with Lutembacher's syndrome remained asymptomatic until the age of 55, when she was treated for exertional dyspnea with digitalis and diuretics. She died of gastrointestinal hemorrhage and hepatic failure at the age of 69. The autopsy revealed a large atrial septal defect and mitral stenosis without rheumatic changes. This patient is the oldest reported survivor of Lutembacher's syndrome with nonrheumatic mitral stenosis.
Assuntos
Comunicação Interatrial/mortalidade , Síndrome de Lutembacher/mortalidade , Idoso , Ecocardiografia , Feminino , Humanos , Síndrome de Lutembacher/diagnóstico por imagem , Síndrome de Lutembacher/patologia , Miocárdio/patologia , Radiografia Torácica , Fatores de TempoAssuntos
Comunicação Interatrial/patologia , Síndrome de Lutembacher/patologia , Arritmias Cardíacas/etiologia , Cateterismo Cardíaco , Eletrocardiografia , Feminino , Humanos , Síndrome de Lutembacher/cirurgia , Pessoa de Meia-Idade , Estenose da Valva Mitral/cirurgia , Edema Pulmonar/prevenção & controleRESUMO
Under study were changes of intraorganic blood vessels of the heart and lungs in some experimental defects (open arterial defect, coarctation of the aorta, simultaneous existence of these two defects, stenosis of the pulmonary trunk, defect of the interatrial septum, triad of Fallot, syndrom of Lutembachet). Morphological data correlated with blood pressure in the pulmonary circulation and cardiac chambers. The complex of compensatory-adaptational mechanisms consisting of comparatively active and passive zones is formed in the heart and lungs. In most cases the changes develop in the vessels already existing. In hypertrophy of the myocardium when there is hypertension and hypervolemia in coronary vessels, sinusoids perform the function of blood reservoir, to a certain degree balancing the blood pressure, and luminar ducts relieve the muscle from excessive blood. The changes in the vascular system of the lung are directly dependent upon the pressure in the pulmonary circulation and the duration of observation. The closing arteries are the most active link in the chain of compensatory-adaptational mechanisms.