Diagnosis and management of pyriform sinus fistula: experience in 48 cases.

PURPOSE: Pyriform sinus fistula (PSF) is often overlooked, and presents diagnostic and management challenge. The aim of this study was to highlight the value of intraoperative endoscopy-assisted intubation or methylene blue injection through the internal opening as a guide in searching for the fistula. METHODS: The charts of 48 patients diagnosed with PSF during January 1990 until January 2013 were retrospectively reviewed. The records were analyzed for sex, side of lesion, age at onset/diagnosis, initial presentations, diagnostic methods, microbiologic cultures, pathologic findings, treatments and outcomes. RESULTS: There were 22 males and 26 females, with a median age at onset and diagnosis of 2 years (range, 8 months to 9 years) and 4 years (range, 12 months to 13 years), respectively. The lesions were predominantly left sided (93.7%). The most common presentation was neck abscess (62.5%). Other presentations were acute suppurative thyroiditis/thyroid abscess (7), neck mass with or without dyspnea (9), and thyroid nodule (2). Barium esophagography showed the sinus tract in 100% cases. The positive predictive value of other modalities was oral-contrast CT 88.9%, intravenous contrast-enhanced CT 53.8%, noncontrast CT 33.3%, and sonography 7.9%. Thyroid function were reported normal in most tested cases (14/15, 93.3%). The fistula tract was lined with pseudostratified squamous epithelium or ciliated columnar epithelium, often associated with inflammatory changes. Bacteria cultured from the discharge were found to be oral flora. Partial thyroidectomy was operated on 11 cases. Two patients (2/8, 25%) who underwent open surgery without endoscopic assistance exhibited recurrence, while no recurrence was noted in children with the help of intraoperative endoscopy. Postoperative results were good in majority (93.7%). CONCLUSION: PSF should be considered in any children with repeated neck or thyroid infection/mass. The combination of barium esophagography, CT scan and ultrasound is useful to establish the diagnosis. Intraoperative endoscopy-assisted intubation or methylene blue injection through the internal opening as a guide can facilitate identification of the tract during dissection.

Imaging studies in sixty patients with acute suppurative thyroiditis.

BACKGROUND: Pyriform sinus fistulae are the major routes of infection in acute suppurative thyroiditis (AST). There have been only a few reports describing imaging studies in AST. We reviewed our imaging studies in patients with AST to elucidate its features so as to facilitate its diagnosis and treatment. METHODS: We reviewed ultrasonography (US) examinations, computed tomography (CT) scans, and barium swallow studies performed on 60 patients with the AST who were seen for medical care between 1998 and 2008 and were retrospectively reviewed. All of these patients had pyriform sinus fistulae. RESULTS: In the acute inflammatory stage, US showed a hypoechoic lesion spreading in and around the affected thyroid lobe, destruction of the lobe, and abscess formation in the neck. CT scans demonstrated similar features with clearer anatomical involvement and edema in the ipsilateral hypopharynx. These findings allowed easy diagnosis of AST. However, in the early inflammatory stage US showed an unclear hypoechoic area in the affected lobe and CT scans showed a nonspecific low-density area. These findings often led to erroneous diagnoses of subacute thyroiditis. A careful review of the US studies demonstrated that the following findings are characteristic of acute suppurative thyroidits: a perithyroidal hypoechoic space, effacement of the plane between the thyroid and perithyroid tissues, and the hypoechoic lesions being unifocal. The former two are not seen in subacute thyroiditis, and hypoechoic lesions in subacute thyroiditis are usually multiple and often bilateral. In the late inflammatory stage, US and CT scans often showed atrophy and an unclear hypoechoic or low-density area in and around the affected lobe. To detect pyriform sinus fistulae, barium swallow studies are more sensitive than US or CT scans. CONCLUSION: During the acute inflammatory stage of AST, both US and CT scans showed inflammatory processes in and around the affected thyroid lobe, although the CT scans more clearly demonstrate the anatomical locations involved. In the early inflammatory stage, these features may lead to an erroneous diagnosis of subacute thyroiditis. Careful US studies should indicate the correct diagnosis, which can then be proven by a barium swallow study or fine-needle aspiration followed by cytological examination and bacterial culturing.

Deep neck infections of congenital causes.

OBJECTIVES: To review cases of deep neck infections with underlying congenital etiology with special emphasis on their clinical presentations and the computed tomographic findings and to discuss the various therapeutic modalities employed for such lesions. STUDY DESIGN: Case series with chart review. SETTINGS: Alexandria University Hospital, Egypt. SUBJECTS AND METHODS: The authors retrospectively reviewed the clinical, imaging, and operative records of deep neck infection cases presented to their department in the past 10 years. Deep neck infection cases due to congenital causes were included in the study. RESULTS Of the 249 cases of deep neck infections admitted to the authors' department in the past 10 years, 39 patients were diagnosed with deep neck infections due to congenital causes. Patients were classified into 2 groups. In group 1 (29 patients), computed tomography revealed the presence of infected cystic swelling in the neck that was classified as second branchial cyst (16 patients), third and fourth branchial cysts (8 patients), and thyroglossal cyst (5 patients). Group 2 (10 patients) presented with recurrent attacks of deep neck infection with a history of incision and drainage several times. Radiological and operative findings revealed the presence of congenital pyriform fossa sinus. CONCLUSION: Computed tomography is helpful in diagnosing infected congenital cysts and its types. Infected congenital cysts could be excised completely under an umbrella of antibiotics. Recurrence of deep neck infections should alert the physician to the possibility of underlying congenital lesions. Thorough clinical and radiological assessment is mandatory to rule out the possibility of a congenital pyriform fossa sinus.