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3.
Dermatol Clin ; 36(4): 397-412, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30201149

RESUMO

Cutaneous adnexal tumors include lesions with apocrine, eccrine, follicular, sebaceous, and mixed differentiation. Most are benign and sporadic, although malignant forms are occasionally observed and some cases develop in the setting of inherited syndromes. These tumors often cause immense diagnostic difficulty. Dermoscopy is a noninvasive technique that has greatly improved the diagnostic accuracy of different skin lesions, including these tumors. We provide a review of the literature on the dermoscopic structures and patterns associated with adnexal tumors. Most patterns associated with this kind of tumor are nonspecific and are observed in other nonadnexal tumors, especially in basal cell carcinomas.


Assuntos
Adenoma/diagnóstico por imagem , Carcinoma/diagnóstico por imagem , Dermoscopia , Doenças do Cabelo/diagnóstico por imagem , Nevo Sebáceo de Jadassohn/diagnóstico por imagem , Neoplasias das Glândulas Sebáceas/diagnóstico por imagem , Glândulas Sebáceas/patologia , Neoplasias das Glândulas Sudoríparas/diagnóstico por imagem , Acrospiroma/diagnóstico por imagem , Síndrome de Birt-Hogg-Dubé/diagnóstico por imagem , Carcinoma Adenoide Cístico/diagnóstico por imagem , Cisto Folicular/diagnóstico por imagem , Hidrocistoma/diagnóstico por imagem , Humanos , Hiperplasia/diagnóstico por imagem , Neoplasia de Células Basais/diagnóstico por imagem , Síndromes Neoplásicas Hereditárias/diagnóstico por imagem , Pilomatrixoma/diagnóstico por imagem , Poroma/diagnóstico por imagem , Neoplasias Cutâneas/diagnóstico por imagem , Siringoma/diagnóstico por imagem , Adenomas Tubulares de Glândulas Sudoríparas/diagnóstico por imagem
4.
Clin Exp Dermatol ; 41(7): 754-6, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27663150

RESUMO

Longitudinal splitting of the nails can occur as a result of any growth arising in the nail matrix. We present a case of a 50-year-old woman who presented with an 18-month history of longitudinal splitting of the nail on her right little finger, along with pain in the proximal nail fold region, which was extremely tender to touch. Magnetic resonance imaging revealed an intensely enhancing lesion, while colour Doppler imaging revealed hypervascularity within the mass. A provisional diagnosis of glomus tumour was considered. Histopathology demonstrated presence of a well-circumscribed tumour comprising a dual population of cells, which stained negatively with periodic-acid-Schiff. The histopathological features were consistent with those of eccrine spiradenoma (ES). In this case, glomus tumour was considered as the first differential diagnosis, but histopathology confirmed it as an ES.


Assuntos
Doenças da Unha/etiologia , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Doenças da Unha/patologia , Doenças da Unha/cirurgia , Neoplasias das Glândulas Sudoríparas/diagnóstico por imagem , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/diagnóstico por imagem , Siringoma/cirurgia
5.
J Clin Ultrasound ; 42(7): 427-9, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24648330

RESUMO

We report the case of a 39-year-old woman complaining of painless unilateral nipple enlargement for 3 weeks. She had no family history of breast cancer. Clinical examination revealed left nipple enlargement without pain, erythema, or skin changes m no associated palpable breast or axillary masses. Ultrasound showed several bright foci in the left nipple suggestive of microcalcifications. Neither solid nor cystic masses were detected. The mammogram performed subsequently confirmed the presence of multiple pleomorphic microcalcifications within the nipple. Wedge biopsy showed a syringomatous adenoma. Wide local excision of the nipple was performed. The postoperative course was uneventful.


Assuntos
Mamografia/métodos , Mamilos , Siringoma/diagnóstico por imagem , Adulto , Biópsia , Diagnóstico Diferencial , Feminino , Humanos , Siringoma/patologia , Ultrassonografia
6.
Clin Imaging ; 34(6): 462-5, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21092877

RESUMO

Infiltrating syringomatous adenoma (ISA) of the nipple, first described by Rosen in 1983 (Am J Surg Pathol, 1983, 7, 739-745), is a rare benign tumor that can be misdiagnosed as a malignancy. ISA is characterized by its specific location in the subareolar region, its distinct histologic appearance resembling sweat duct or syringomatous tumors, and its locally infiltrating growth. We describes a case of ISA of the nipple presenting as microcalcification that was found on screening mammography. We also reviewed previously reported radiologic features of ISA.


Assuntos
Neoplasias da Mama/complicações , Neoplasias da Mama/diagnóstico por imagem , Calcinose/complicações , Calcinose/diagnóstico por imagem , Mamilos/diagnóstico por imagem , Siringoma/complicações , Siringoma/diagnóstico por imagem , Diagnóstico Diferencial , Feminino , Humanos , Mamografia , Programas de Rastreamento , Pessoa de Meia-Idade
7.
Breast J ; 15(4): 414-6, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19470133

RESUMO

Infiltrating syringomatous adenoma of the nipple is a rare, benign, locally invasive tumor with recurrence potential, showing sweat duct differentiation. It can clinically, radiologically and pathologically mimic cancer. Histopathologically, it must be distinguished from florid papillomatosis, adenosquamous carcinoma, adenoid cystic carcinoma and sclerosing syringomatous carcinoma. A 44-year-old woman presented with pain on the right nipple for 7 days. On physical exam there was an irregular nodule on nipple area with edema. The skin was intact. The ultrasound showed a hypoechoic irregular nodule measuring 7.5 mm in the nipple area. The mammography was unspecific. The lesion was surgically removed and histopathologically, the tumor was composed of ducts and tubules lined with a double-layered epithelial cells. The lining cells were small, cuboidal with a central nuclei and eosinophilic nuclei. The stroma was dense with lymphocytes and plasma cells, and compressed many of the ducts that contained a comma or tadpole-shape, giving an impression of a syringoma. Some ducts were slightly dilated with squamous metaplasia. Some of these cysts were connected with the overlying epidermis. Mitotic figures were rare and no pleomorfism or hyperchromasia was observed. At the periphery, the ducts invaded muscular fibers of the nipple. The surgical margins were free of neoplastic involvement. Patient has no signs of progression of disease in 1 year of follow-up.


Assuntos
Adenoma/cirurgia , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Mamilos/patologia , Siringoma/cirurgia , Adenoma/diagnóstico por imagem , Adenoma/patologia , Adulto , Neoplasias da Mama/diagnóstico por imagem , Feminino , Humanos , Mamilos/cirurgia , Siringoma/diagnóstico por imagem , Siringoma/patologia , Resultado do Tratamento , Ultrassonografia
8.
Acta Cytol ; 43(2): 303-7, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10097731

RESUMO

BACKGROUND: Infiltrating syringomatous adenoma is a rare tumor of the breast that can radiologically mimic invasive duct carcinoma. Detailed fine needle aspiration cytology and needle core biopsy findings on this lesion have not been previously described. CASE: The clinical, radiologic and pathologic findings of an infiltrating syringomatous adenoma of the breast in a 71-year-old female who presented with a subareolar lump are described. The cytology of the tumor was characterized by a combination of a background of plump, fibroblastoid cells and cohesive sheets of bland epithelial cells. Histologically the tumor showed infiltrating, duct-like structures with squamous metaplasia and a desmoplastic stroma. CONCLUSION: Fine needle aspiration cytology and needle core biopsy can distinguish infiltrating syringomatous adenoma from malignant disease of the breast.


Assuntos
Neoplasias da Mama/patologia , Siringoma/patologia , Idoso , Biópsia por Agulha , Neoplasias da Mama/diagnóstico por imagem , Células Epiteliais/química , Células Epiteliais/patologia , Feminino , Humanos , Queratinas/análise , Mamografia , Siringoma/diagnóstico por imagem , Ultrassonografia
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