[Thin-layer chromatographic determination of pyrantel in cow's milk and blood serum after oral administration of Banminth]. / Dünnschichromatographische Bestimmung von Pyrantel in Kuhmilch und Blutserum nach peroraler Applikation von Banminth.

After oral administration of the anthelmintic Banminth to cows the effective agent pyrantel appeared unchanged in blood serum and milk. After a therapeutic dose of 12,1 mg pyrantel tartrate/kg body weight, a maximum level of 8-9 micrograms/l could be found in milk 0-24 h after the application; the highest concentration of 22 micrograms/l in blood serum appeared after 10 h and the half-life time of elimination was ca. 15 h. Pyrantel determination in milk and blood serum was performed by quantitative thin layer chromatography. Positive results could be verified by HPLC.