RESUMO
Cerebral involvement in hydatid disease occurs in 1-4% of cases. There are few documented cases in the literature of intracranial hydatid cysts in unusual locations such as pons and thalamus. In this report, a case of 33-year-old male with primary intracranial hydatid cyst in the interpeduncular cistern is reported. This is the first such case in the literature.
Assuntos
Encefalopatias/cirurgia , Infecções Parasitárias do Sistema Nervoso Central/cirurgia , Equinococose/cirurgia , Tegmento Mesencefálico/cirurgia , Adulto , Albendazol/administração & dosagem , Encefalopatias/diagnóstico , Infecções Parasitárias do Sistema Nervoso Central/diagnóstico , Infecções Parasitárias do Sistema Nervoso Central/patologia , Terapia Combinada , Craniotomia , Diagnóstico Diferencial , Equinococose/diagnóstico , Equinococose/patologia , Hemianopsia/etiologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Cuidados Pós-Operatórios , Tegmento Mesencefálico/parasitologia , Tegmento Mesencefálico/patologia , Tomografia Computadorizada por Raios XRESUMO
We investigated whether the infection with Trypanosoma cruzi in rats could produce functional alterations of the central nervous system. The experimental group received an injection of 150,000 trypomastigotes / rat, whereas the control group received a saline injection. Spontaneous alternation behavior (SAB) tests and sleep-wake cycle recordings were obtained at the end of the parasitaemia. Results showed that the infected animals had significant sleep impairments, as denoted by an increase in the number of wake periods and a reduction of rapid eye movement sleep amount. SAB performance was also found to be impaired in these animals, as compared to the control group. Our results suggest that the rat is a suitable model for brain dysfunction studies in Chagas' disease.
