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1.
J Clin Exp Neuropsychol ; 46(1): 67-79, 2024 02.
Artigo em Inglês | MEDLINE | ID: mdl-38362939

RESUMO

OBJECTIVE: To adjust the decision criterion for the Word Memory Test (WMT, Green, 2003) to minimize the frequency of false positives. METHOD: Archival data were combined into a database (n = 3,210) to examine the best cut score for the WMT. We compared results based on the original scoring rules and those based on adjusted scoring rules using a criterion based on 16 performance validity tests (PVTs) exclusive of the WMT. Cutoffs based on peer-reviewed publications and test manuals were used. The resulting PVT composite was considered the best estimate of validity status. We focused on a specificity of .90 with a false-positive rate of less than .10 across multiple samples. RESULTS: Each examinee was administered the WMT, as well as on average 5.5 (SD = 2.5) other PVTs. Based on the original scoring rules of the WMT, 31.8% of examinees failed. Using a single failure on the criterion PVT (C-PVT), the base rate of failure was 45.9%. When requiring two or more failures on the C-PVT, the failure rate dropped to 22.8%. Applying a contingency analysis (i.e., X2) to the two failures model on the C-PVT measure and using the original rules for the WMT resulted in only 65.3% agreement. However, using our adjusted rules for the WMT, which consisted of relying on only the IR and DR WMT subtest scores with a cutoff of 77.5%, agreement between the adjusted and the C-PVT criterion equaled 80.8%, for an improvement of 12.1% identified. The adjustmeny resulted in a 49.2% reduction in false positives while preserving a sensitivity of 53.6%. The specificity for the new rules was 88.8%, for a false positive rate of 11.2%. CONCLUSIONS: Results supported lowering of the cut score for correct responding from 82.5% to 77.5% correct. We also recommend discontinuing the use of the Consistency subtest score in the determination of WMT failure.


Assuntos
Testes Neuropsicológicos , Humanos , Feminino , Masculino , Adulto , Reações Falso-Positivas , Pessoa de Meia-Idade , Testes Neuropsicológicos/normas , Adulto Jovem , Idoso , Simulação de Doença/diagnóstico , Adolescente , Testes de Memória e Aprendizagem/normas , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
2.
J Clin Exp Neuropsychol ; 46(1): 36-45, 2024 02.
Artigo em Inglês | MEDLINE | ID: mdl-38402625

RESUMO

OBJECTIVE: Pupillometry provides information about physiological and psychological processes related to cognitive load, familiarity, and deception, and it is outside of conscious control. This study examined pupillary dilation patterns during a performance validity test (PVT) among adults with true and feigned impairment of traumatic brain injury (TBI). PARTICIPANTS AND METHODS: Participants were 214 adults in three groups: adults with bona fide moderate to severe TBI (TBI; n = 51), healthy comparisons instructed to perform their best (HC; n = 72), and healthy adults instructed and incentivized to simulate cognitive impairment due to TBI (SIM; n = 91). The Recognition Memory Test (RMT) was administered in the context of a comprehensive neuropsychological battery. Three pupillary indices were evaluated. Two pure pupil dilation (PD) indices assessed a simple measure of baseline arousal (PD-Baseline) and a nuanced measure of dynamic engagement (PD-Range). A pupillary-behavioral index was also evaluated. Dilation-response inconsistency (DRI) captured the frequency with which examinees displayed a pupillary familiarity response to the correct answer but selected the unfamiliar stimulus (incorrect answer). RESULTS: All three indices differed significantly among the groups, with medium-to-large effect sizes. PD-Baseline appeared sensitive to oculomotor dysfunction due to TBI; adults with TBI displayed significantly lower chronic arousal as compared to the two groups of healthy adults (SIM, HC). Dynamic engagement (PD-Range) yielded a hierarchical structure such that SIM were more dynamically engaged than TBI followed by HC. As predicted, simulators engaged in DRI significantly more frequently than other groups. Moreover, subgroup analyses indicated that DRI differed significantly for simulators who scored in the invalid range on the RMT (n = 45) versus adults with genuine TBI who scored invalidly (n = 15). CONCLUSIONS: The findings support continued research on the application of pupillometry to performance validity assessment: Overall, the findings highlight the promise of biometric indices in multimethod assessments of performance validity.


Assuntos
Lesões Encefálicas Traumáticas , Disfunção Cognitiva , Simulação de Doença , Testes Neuropsicológicos , Pupila , Reconhecimento Psicológico , Humanos , Masculino , Feminino , Adulto , Reconhecimento Psicológico/fisiologia , Simulação de Doença/diagnóstico , Simulação de Doença/fisiopatologia , Lesões Encefálicas Traumáticas/complicações , Lesões Encefálicas Traumáticas/fisiopatologia , Disfunção Cognitiva/fisiopatologia , Disfunção Cognitiva/etiologia , Disfunção Cognitiva/diagnóstico , Pessoa de Meia-Idade , Pupila/fisiologia , Testes Neuropsicológicos/normas , Adulto Jovem , Testes de Memória e Aprendizagem/normas
3.
PLoS One ; 16(10): e0259279, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34714869

RESUMO

Studies examining age effects in autobiographical memory have produced inconsistent results. This study examined whether a set of typical autobiographical memory measures produced equivalent results in a single participant sample. Five memory tests (everyday memory, autobiographical memory from the past year, autobiographical memory from age 11-17, word-cued autobiographical memory, and word-list recall) were administered in a single sample of young and older adults. There was significant variance in the tests' sensitivity to age: word-cued autobiographical memory produced the largest deficit in older adults, similar in magnitude to word-list recall. In contrast, older adults performed comparatively well on the other measures. The pattern of findings was broadly consistent with the results of previous investigations, suggesting that (1) the results of the different AM tasks are reliable, and (2) variable age effects in the autobiographical memory literature are at least partly due to the use of different tasks, which cannot be considered interchangeable measures of autobiographical memory ability. The results are also consistent with recent work dissociating measures of specificity and detail in autobiographical memory, and suggest that specificity is particularly sensitive to ageing. In contrast, detail is less sensitive to ageing, but is influenced by retention interval and event type. The extent to which retention interval and event type interact with age remains unclear; further research using specially designed autobiographical memory tasks could resolve this issue.


Assuntos
Envelhecimento/fisiologia , Testes de Memória e Aprendizagem/normas , Memória Episódica , Adulto , Idoso , Idoso de 80 Anos ou mais , Sinais (Psicologia) , Feminino , Humanos , Masculino , Sensibilidade e Especificidade
4.
Sci Rep ; 11(1): 21177, 2021 10 27.
Artigo em Inglês | MEDLINE | ID: mdl-34707108

RESUMO

Spatial working memory can be assessed in mice through the spontaneous alternation T-maze test. The T-maze is a T-shaped apparatus featuring a stem (start arm) and two lateral goal arms (left and right arms). The procedure is based on the natural tendency of rodents to prefer exploring a novel arm over a familiar one, which induces them to alternate the choice of the goal arm across repeated trials. During the task, in order to successfully alternate choices across trials, an animal has to remember which arm had been visited in the previous trial, which makes spontaneous alternation T-maze an optimal test for spatial working memory. As this test relies on a spontaneous behaviour and does not require rewards, punishments or pre-training, it represents a particularly useful tool for cognitive evaluation, both time-saving and animal-friendly. We describe here in detail the apparatus and the protocol, providing representative results on wild-type healthy mice.


Assuntos
Aprendizagem em Labirinto , Testes de Memória e Aprendizagem/normas , Animais , Memória de Curto Prazo , Camundongos , Memória Espacial
5.
Schizophr Bull ; 47(3): 740-750, 2021 04 29.
Artigo em Inglês | MEDLINE | ID: mdl-33219382

RESUMO

Smartphone-based ecological mobile cognitive tests (EMCTs) can measure cognitive abilities in the real world, complementing traditional neuropsychological assessments. We evaluated the validity of an EMCT of recognition memory designed for use with people with serious mental illness, as well as relevant contextual influences on performance. Participants with schizophrenia (SZ), schizoaffective disorder, and bipolar disorder (BD) completed in-lab assessments of memory (Hopkins Verbal Learning Test, HVLT), other cognitive abilities, functional capacity, and symptoms, followed by 30 days of EMCTs during which they completed our Mobile Variable Difficulty List Memory Test (VLMT) once every other day (3 trials per session). List length on the VLMT altered between 6, 12, and 18 items. On average, participants completed 75.3% of EMCTs. Overall performance on VLMT 12 and 18 items was positively correlated with HVLT (ρ = 0.52, P < .001). People with BD performed better on the VLMT than people with SZ. Intraindividual variability on the VLMT was more specifically associated with HVLT than nonmemory tests and not associated with symptoms. Performance during experienced distraction, low effort, and out of the home location was reduced yet still correlated with the in-lab HVLT. The VLMT converged with in-lab memory assessment, demonstrating variability within person and by different contexts. Ambulatory cognitive testing on participants' personal mobile devices offers more a cost-effective and "ecologically valid" measurement of real-world cognitive performance.


Assuntos
Transtorno Bipolar/fisiopatologia , Disfunção Cognitiva/diagnóstico , Disfunção Cognitiva/fisiopatologia , Avaliação Momentânea Ecológica/normas , Testes de Memória e Aprendizagem/normas , Transtornos Psicóticos/fisiopatologia , Reconhecimento Psicológico/fisiologia , Esquizofrenia/fisiopatologia , Telemedicina/normas , Adolescente , Adulto , Idoso , Transtorno Bipolar/complicações , Disfunção Cognitiva/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Aplicativos Móveis , Transtornos Psicóticos/complicações , Reprodutibilidade dos Testes , Esquizofrenia/complicações , Smartphone , Adulto Jovem
6.
Appl Neuropsychol Adult ; 28(1): 35-47, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-30950290

RESUMO

It is critical that we develop more efficient performance validity tests (PVTs). A shorter version of the Test of Memory Malingering (TOMM) that utilizes errors on the first 10 items (TOMMe10) has shown promise as a freestanding PVT. Retrospective review included 397 consecutive veterans administered TOMM trial 1 (TOMM1), the Medical Symptom Validity Test (MSVT), and the Brief Visuospatial Memory Test-Revised (BVMT-R). TOMMe10 accuracy and administration time were used to predict performance on freestanding PVTs (TOMM1, MSVT). The impact of failing TOMMe10 (2 or more errors) on independent memory measures was also explored. TOMMe10 was a robust predictor of TOMM1 (area under the curve [AUC] = 0.97) and MSVT (AUC = 0.88) with sensitivities = 0.76 to 0.89 and specificities = 0.89 to 0.96. Administration time predicted PVT performance but did not improve accuracy compared to TOMMe10 alone. Failing TOMMe10 was associated with clinically and statistically significant declines on the BVMT-R and MSVT Paired Associates and Free Recall memory tests (d = -0.32 to -1.31). Consistent with prior research, TOMMe10 at 2 or more errors was highly accurate in predicting performance on other well-validated freestanding PVTs. Failing just 1 freestanding PVT (TOMMe10) significantly impacted memory measures and likely reflects invalid test performance.


Assuntos
Disfunção Cognitiva/diagnóstico , Simulação de Doença/diagnóstico , Transtornos da Memória/diagnóstico , Testes de Memória e Aprendizagem/normas , Psicometria/normas , Desempenho Psicomotor , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Sensibilidade e Especificidade , Veteranos
7.
Clin Neuropsychol ; 34(sup1): 127-142, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33025851

RESUMO

OBJECTIVE: The aim of this study was to create sex-, age- and education-adjusted norms for the WHO/UCLA version of the Rey Auditory Verbal Learning Test (RAVLT) for Sinhala-speaking Sri Lankan adults. METHODS: Five-hundred and sixty-one healthy, community-living adults (252 men), aged 19-83 years, and had 0-23 years of education completed the WHO/UCLA RAVLT in Sinhala language. We conducted multiple linear regression analyses with sex, age and years of education to predict RAVLT list A1-A5 individual trial scores; trials A1-A5 total learning; list B score; immediate and delayed recall and recognition trial scores; and retroactive interference. RESULTS: We report regression equations to predict RAVLT norms based on sex, age and years of education; and the test variances accounted by those variables. Accordingly, all measures, except retroactive interference had a significant age-related decline. All measures, except the recognition trial hits, significantly improved with more years of education. Women had significantly higher scores in all measures except in trial B and retroactive interference. Proactive interference, learning rate, learning over trials were not associated with sex, age or education. A confirmatory factor analysis loaded the RAVLT outcome measures into two factors: acquisition and retention. CONCLUSIONS: We report sex-, age- and education-adjusted WHO/UCLA RAVLT norms for Sinhala-speaking Sri Lankans aged 19-83 years; and supplement the regression formulae with a calculator that produces predicted and standard scores for given test participant. These norms would help clinicians accurately interpret individual test results, accounting for the variability introduced by sex, age and education.


Assuntos
Testes de Memória e Aprendizagem/normas , Testes Neuropsicológicos/normas , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Idioma , Masculino , Pessoa de Meia-Idade , Fatores Sexuais , Sri Lanka , Organização Mundial da Saúde , Adulto Jovem
8.
J Clin Exp Neuropsychol ; 42(5): 505-515, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32567997

RESUMO

BACKGROUND: Tests of verbal memory (list learning) are particularly useful for clinicians and researchers globally, yet there are no psychometrically robust tests that are built indigenously for Arabic-speaking populations, which comprise more than 370 million. OBJECTIVE: To develop a verbal memory Arabic test using a systematic procedure of item selection and then provide evidence of validity and reliability in an Arabic-speaking sample in Lebanon. METHOD: In study 1, we conducted a word prototypicality study (n = 77), and identified 932 words across 7 semantic categories. Following quantitative analyzes and qualitative judgments by an expert panel, we selected a sufficient number of words and categories, and constructed and piloted the items, instructions, and protocol for the Verbal Memory Arabic Test (VMAT). In study 2, we administered the VMAT on a community sample (n = 199; screened for depression and cognitive impairment) and patients with Multiple Sclerosis (n = 16). RESULTS: Scores decreased with age as expected, they discriminated well between healthy and clinical populations (matched on age, sex, and years of education), and showed acceptable consistency within items and across time. Conclusions: The VMAT is the first Arabic test developed indigenously. It can be used in clinical and research settings with Arabic-speaking populations to assess verbal learning.


Assuntos
Disfunção Cognitiva/diagnóstico , Testes de Memória e Aprendizagem/normas , Psicometria/normas , Aprendizagem Verbal , Adulto , Árabes , Disfunção Cognitiva/etiologia , Depressão/complicações , Feminino , Humanos , Líbano , Masculino , Pessoa de Meia-Idade , Esclerose Múltipla/complicações , Projetos Piloto , Psicometria/instrumentação , Psicometria/métodos , Valores de Referência , Reprodutibilidade dos Testes , Aprendizagem Verbal/fisiologia
9.
Appl Neuropsychol Child ; 9(4): 355-359, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32401052

RESUMO

We evaluated the classification accuracy of two abbreviated versions of the Test of Memory Malingering (TOMM) in prediction of results on the full-length instrument in a sample of 126 children who were evaluated within 1-12 months after traumatic brain injury. Both a version based on administration of Trial 1 and a version based on administration of only the first 10 items of Trial 1 had acceptable specificity (i.e., > .90) and sensitivity (i.e., > .60) with regard to prediction of pass/fail results on the complete TOMM. Failure on the TOMM suppressed performance on measures of processing speed that were otherwise sensitive to severity of traumatic brain injury. We conclude that these abbreviated versions of the TOMM can be used in clinical practice with children with traumatic brain injury, at the discretion of the neuropsychologist.


Assuntos
Lesões Encefálicas Traumáticas/diagnóstico , Lesões Encefálicas Traumáticas/psicologia , Simulação de Doença/diagnóstico , Simulação de Doença/psicologia , Testes de Memória e Aprendizagem/normas , Adolescente , Criança , Feminino , Humanos , Masculino , Reprodutibilidade dos Testes
10.
Appl Neuropsychol Child ; 9(4): 292-306, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32372667

RESUMO

Growing recognition and concerns of non-credible performance in pediatric populations have led clinicians to investigate the utility of performance and symptom validity tests (PVT/SVTs) among children and adolescents. Yet current research has indicated that a minority of clinicians routinely utilize a free-standing PVT in pediatric neuropsychological evaluations. The current article investigates the rationale for using PVT/SVTs, and the impact that failure of such exams have on other neurocognitive tests. A review of common adult PVTs and their appropriateness for use with specific pediatric clinical populations is presented, as well as empirical evidence for evaluating embedded validity indicators. The limited literature on SVTs with youth is also reviewed and provides additional insight into symptom exaggeration. There are various reasons children would provide noncredible performance, many of which are different from adults. A review of how the clinician should handle this behavior in pediatric evaluations is provided and what patient populations may present with a higher base rate of failure. Finally, various approaches are offered on how to explain these results to children and their caregivers.


Assuntos
Simulação de Doença/diagnóstico , Simulação de Doença/psicologia , Testes de Memória e Aprendizagem/normas , Vigilância da População , Criança , Humanos , Testes Neuropsicológicos/normas , Vigilância da População/métodos , Reprodutibilidade dos Testes , Avaliação de Sintomas/métodos , Avaliação de Sintomas/normas , Teste de Classificação de Cartas de Wisconsin/normas
11.
Mult Scler Relat Disord ; 42: 102072, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32330844

RESUMO

BACKGROUND: Cognitive impairment has been recognized as an important factor in multiple sclerosis (MS) in the past few years. One brief, reliable and valid tool to assess cognition in MS is the BICAMS, which encompasses the Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test (CVLT II), and the Brief Visuospatial Memory Test - Revised (BVMT-R). Continuing with the international initiative to validate the BICAMS in different countries, here we present the results obtained from the efforts in validating such test in the Colombian population. METHOD: 100 healthy controls and 50 MS patients participated in the study, group matched for age, education and gender. Subjects completed all three tests of the BICAMS. Instead of the CVLT-II, the Colombian validated form PAMCL (Prueba de Aprendizaje y Memoria con Codificación Libre) was used. Test-retest measures were obtained for 16 patients in order to test for reliability. RESULTS: Evidence of criterion validity was obtained, MS group performing significantly worse than HC group in all three tests (SDMT: p= .001, d= 0.59; PAMCL: p= .03, d= 0.38; BVMT-R: p<.001, d= 0.58). Test-retest was also obtained, finding significant correlations for all three tests (SDMT: r=0.932, p<.00; BVMT-R: r=0.863, p<.001; PAMCL: r=0.889, p<.001). Standardization of raw scores to uncontrolled scaled scores was done and these scores were then adjusted for age and years of schooling using a multiple linear regression. CONCLUSIONS: The BICAMS proved to be a valid and sensitive tool to screen for cognitive impairment in MS patients.


Assuntos
Disfunção Cognitiva/diagnóstico , Esclerose Múltipla/diagnóstico , Testes Neuropsicológicos/normas , Adulto , Disfunção Cognitiva/etiologia , Colômbia , Feminino , Humanos , Masculino , Testes de Memória e Aprendizagem/normas , Pessoa de Meia-Idade , Esclerose Múltipla/complicações , Reprodutibilidade dos Testes , Adulto Jovem
12.
Cogn Behav Neurol ; 33(1): 16-22, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32132399

RESUMO

BACKGROUND: Verbal memory impairment in individuals with Huntington disease (HD) is well-documented; however, the nature and extent of verbal memory impairment in individuals with premanifest HD (pre-HD) are less understood. OBJECTIVE: To evaluate verbal memory function in individuals with pre-HD by comparing their performance on the California Verbal Learning Test to that of individuals with a clinical diagnosis of HD and that of a demographically similar group of adults with no family history of, or genetic risk for, HD, thereby reducing possible complications of psychiatric difficulties commonly experienced by individuals who are at risk for HD but are gene negative. METHODS: Participant groups included 77 adults with a diagnosis of HD, 23 premanifest gene carriers for HD (pre-HD), and 54 demographically similar, healthy adults. The California Verbal Learning Test-Second Edition (CVLT-II) was used to evaluate the participants' immediate and delayed recall, recognition, learning characteristics, errors, and memory retention. RESULTS: The pre-HD group performed significantly worse than the healthy group, yet significantly better than the HD group, on Short and Long Delay Recall (Free and Cued) and Recognition Discriminability. On Total Immediate Recall, Learning Slope, Semantic Clustering, and Intrusions, the pre-HD group performed similarly to the healthy group and significantly better than the HD group. None of the groups differed in their performance on Repetitions and a measure of retention. CONCLUSIONS: Subtle memory deficits can be observed during the premanifest stage of HD with use of a subset of indices from the CVLT-II.


Assuntos
Doença de Huntington/complicações , Transtornos da Memória/etiologia , Testes de Memória e Aprendizagem/normas , Rememoração Mental/fisiologia , Testes Neuropsicológicos/normas , Aprendizagem Verbal/fisiologia , Adulto , Feminino , Humanos , Doença de Huntington/patologia , Masculino , Transtornos da Memória/patologia , Pessoa de Meia-Idade
13.
Appl Neuropsychol Child ; 9(4): 337-354, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32081042

RESUMO

Objective: This study was designed to examine the classification accuracy of verbal fluency (VF) measures as performance validity tests (PVT).Method: Student volunteers were assigned to the control (n = 57) or experimental malingering (n = 24) condition. An archival sample of 77 patients with TBI served as a clinical comparison.Results: Among students, FAS T-score ≤29 produced a good combination of sensitivity (.40-.42) and specificity (.89-.95). Animals T-score ≤31 had superior sensitivity (.53-.71) at .86-.93 specificity. VF tests performed similarly to commonly used PVTs embedded within Digit Span: RDS ≤7 (.54-.80 sensitivity at .93-.97 specificity) and age-corrected scaled score (ACSS) ≤6 (.54-.67 sensitivity at .94-.96 specificity). In the clinical sample, specificity was lower at liberal cutoffs [animals T-score ≤31 (.89-.91), RDS ≤7 (.86-.89) and ACSS ≤6 (.86-.96)], but comparable at conservative cutoffs [animals T-score ≤29 (.94-.96), RDS ≤6 (.95-.98) and ACSS ≤5 (.92-.96)].Conclusions: Among students, VF measures had higher signal detection performance than previously reported in clinical samples, likely due to the absence of genuine impairment. The superior classification accuracy of animal relative to letter fluency was replicated. Results suggest that existing validity cutoffs can be extended to cognitively high functioning examinees, and emphasize the importance of population-specific cutoffs.


Assuntos
Lesões Encefálicas Traumáticas/psicologia , Simulação de Doença/psicologia , Testes de Memória e Aprendizagem/normas , Desempenho Psicomotor/fisiologia , Fala/fisiologia , Comportamento Verbal/fisiologia , Adolescente , Adulto , Lesões Encefálicas Traumáticas/diagnóstico , Lesões Encefálicas Traumáticas/fisiopatologia , Feminino , Humanos , Masculino , Simulação de Doença/diagnóstico , Simulação de Doença/fisiopatologia , Reprodutibilidade dos Testes , Adulto Jovem
14.
Psychol Assess ; 32(5): 442-450, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32027161

RESUMO

Current standards of practice in neuropsychology advocate for including validity tests (PVTs). Abbreviating PVTs, such as the Test of Memory Malingering (TOMM), may help reduce overall evaluation time while maintaining diagnostic accuracy. TOMM Trial 1 performance (T1), as well as the number of errors within the first 10 items of Trial 1 (TOMMe10), have shown initial promise as abbreviated PVTs but require additional external cross-validation. This study sought to replicate findings from other mixed, diverse, clinical samples and provide further validation of abbreviated administrations of the TOMM. Data included 120 veterans who completed the TOMM and 3 criterion PVTs during clinical evaluation. In total, performance from 68% of the sample was classified as valid (52% met criteria for cognitive impairment), and performance from 32% of the sample was invalid. Group differences, diagnostic accuracy statistics, and receiver operating characteristic (ROC) curves were analyzed for relevant TOMM indices. There were large (η²p= .45-.66), significant differences between validity groups (p < .001) on TOMM T1 and TOMMe10, with lower TOMM T1 and higher TOMMe10 scores for participants with invalid performance. Using established cut-scores, sensitivities/specificities were: TOMMe10 ≥1 error: .84/.66; ≥2 errors: .74/.93; TOMM T1 ≤40: .82/.93. ROC curve analysis yielded significant areas under the curve for both TOMMe10 and T1 with respective optimal cut-scores of ≥2 errors (.74 sensitivity/.93 specificity) and ≤41 (.84 sensitivity/.91 specificity). TOMMe10 and T1 performances are minimally impacted by cognitive impairment. Although both evidenced robust psychometric properties, TOMM T1 continued to show greater accuracy than TOMMe10. (PsycInfo Database Record (c) 2020 APA, all rights reserved).


Assuntos
Disfunção Cognitiva/diagnóstico , Simulação de Doença/diagnóstico , Transtornos da Memória/diagnóstico , Testes de Memória e Aprendizagem/normas , Testes Neuropsicológicos/normas , Análise e Desempenho de Tarefas , Veteranos , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes
15.
Child Neuropsychol ; 26(6): 801-816, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-31937183

RESUMO

This study examined the performance of children consecutively admitted to an inpatient psychiatric unit on the Test of Memory Malingering (TOMM) (aged 5-12; n = 96) and Automatized Sequences Task (aged 8-12; n = 67). Eighty-three percent of children passed the TOMM Trial 2 (M raw score = 47.7, SD = 4.7) and 76% of children passed the Automatized Sequences Task total time (M = 23.1 seconds; SD = 8.2). The concordance rate between the TOMM and the total time on the Automatized Sequences Task was 73.1%. Receiver operating characteristic curves indicated that of the Automatized Sequences Task subtests, only Counting 1-20 significantly differentiated children who passed Trial 2 of the TOMM from those who did not pass Trial 2 of the TOMM (area under the curve = .756, p = .006). Performance on both PVTs was unrelated to demographic characteristics and measures of psychological and neuropsychological functioning on both the TOMM and Automatized Sequences Task. Further research is needed to determine whether the nearly 1 in 4 children (23.9%) who performed below recommended cutoffs on Automatized Sequences Task reflects genuine suboptimal effort, cognitive difficulties among these children, and/or other factors.


Assuntos
Simulação de Doença/psicologia , Testes de Memória e Aprendizagem/normas , Testes Neuropsicológicos/normas , Criança , Pré-Escolar , Feminino , Humanos , Pacientes Internados , Masculino
16.
Appl Neuropsychol Child ; 9(4): 329-336, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31918597

RESUMO

In pediatric evaluations, performance validity test (PVT) selection is often constrained by reading level, developmental appropriateness of stimuli, and administration time. The Rey 15 Item Test (FIT) addresses these constraints, and ranks among the most frequently used PVTs. Unfortunately, research indicates poor sensitivity of the FIT recall trial. Boone et al. developed a FIT recognition trial and demonstrated in an adult sample that its use increased sensitivity while maintaining high specificity. These results are promising, but, to the authors' knowledge, have only been replicated once in a pediatric sample. The present study examined the FIT plus recognition trial in a sample of 72 young athletes ages 8-16 years. All data for the present study were collected during baseline cognitive evaluations. The Test of Memory Malingering (TOMM) was used as the comparison criterion. Receiver operating characteristic curve analyses showed the addition of the recognition trial did not substantially improve sensitivity of the FIT. There was a surprising lack of concordance between TOMM and FIT scores, and, whereas the FIT correlated with multiple cognitive measures, the TOMM did not correlate with any other measures. Results suggest the FIT is not appropriate for pediatric clinical care, even with the additional recognition trial.


Assuntos
Vida Independente/psicologia , Simulação de Doença/diagnóstico , Simulação de Doença/psicologia , Testes de Memória e Aprendizagem/normas , Reconhecimento Psicológico/fisiologia , Adolescente , Traumatismos em Atletas/diagnóstico , Traumatismos em Atletas/psicologia , Concussão Encefálica/diagnóstico , Concussão Encefálica/psicologia , Criança , Feminino , Humanos , Masculino , Testes Neuropsicológicos/normas , Reprodutibilidade dos Testes
17.
Clin Neuropsychol ; 34(1): 88-119, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31357918

RESUMO

Objective: The present study, adhering to Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) guidelines, is the first systematic review and meta-analysis of the Test of Memory Malingering (TOMM) to examine traditional and alternative cutoffs across Trial 1, Trial 2, and Retention.Method: Search criteria identified 539 articles published from 1997 to 2017. After application of selection criteria, 60 articles were retained for meta-analysis. Classification accuracy statistics were calculated using fixed- and random-effects models.Results: For Trial 1, a cutoff of <42 was found to result in the highest sensitivity value (0.59-0.70) when maintaining specificity at ≥0.90. Traditional cutoffs for Trial 2 and Retention were highly specific (0.96-0.98) and moderately sensitive (0.46-0.56) when considering all available studies and only neurocognitive/psychiatric samples classified by known-groups design. For both trials, a modified cutoff of <49 allowed for improved sensitivity (0.59-0.70) while maintaining adequate specificity (0.91-0.97). A supplementary review revealed that traditional TOMM cutoffs produced >0.90 specificity across most samples of examinees for whom English is not the primary language, but well-below acceptable levels in individuals with dementia.Conclusions: The TOMM is highly specific when interpreted per traditional cutoffs. In individuals not suspected of significant impairment, findings indicate that a less conservative TOMM Trial 2 or Retention cutoff of <49 can be interpreted as invalid, especially in settings associated with higher base rates of invalidity and, thus, higher positive predictive power. A cutoff of <42 on Trial 1 can also be interpreted as invalid in most settings.


Assuntos
Simulação de Doença/diagnóstico , Testes de Memória e Aprendizagem/normas , Testes Neuropsicológicos/normas , Feminino , Humanos , Masculino
18.
Clin Neuropsychol ; 34(2): 384-405, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31322042

RESUMO

Objective: To detect cognitive "impairment," neuropsychologists rely on normative data to compare patient performance to "normal" peers. However, the true normality of normative samples may be called into question given the high prevalence of preclinical proteinopathies amongst clinically normal older adults. Given its common use in memory clinics, we aimed to develop a robust California Verbal Learning Test (CVLT) normative standard reflecting only the most cognitively stable sample of older adults available.Method: Two hundred and twenty-eight older adults (mean age = 69.9, range = 60-89, 91% White, mean education = 17.6 years) who were clinically normal at baseline and demonstrated clinical stability on longitudinal assessment completed the CVLT at baseline. We applied a standardized algorithm to convert raw scores into normalized scaled scores and then regressed on age, sex, and education using fractional polynomial modeling.Results: There were significant main effects of age and sex across CVLT metrics, but not education. Means and standard deviations were higher and less variable in our robust normative data than the data used to create the CVLT-II and CVLT-3 normative standards.Conclusions: These norms set a higher standard for what should be considered "normal" in the spectrum of age-related memory changes and may help clinicians identify patients with memory and potential neurodegenerative changes in the earliest stages, further optimizing clinical management and clinical trial stratification. As with any standard, these robust norms are only appropriately utilized with patients that closely match the demographic profile of the individuals represented in the sample used for this study.


Assuntos
Transtornos da Memória/diagnóstico , Testes de Memória e Aprendizagem/normas , Testes Neuropsicológicos/normas , Idoso , Idoso de 80 Anos ou mais , Diagnóstico Precoce , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
19.
Clin Neuropsychol ; 34(3): 541-560, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31084399

RESUMO

Objective: We investigated the construct and criterion validity of the source memory (SM) indices within the California Verbal Learning Test-II (CVLT-II).Method: Participants included 77 individuals with HIV-associated neurocognitive disorders (HAND+), 287 HIV + neurocognitively normal individuals (HAND-) and 203 seronegative HIV comparisons (HIV-). CVLT-II SM impairment status (normative scores ≤1 standard deviation) was determined using Total Across-List Intrusions and Source Recognition Discriminability (d'). Participants also completed a comprehensive neuropsychological battery, assessments of everyday functioning and experimental measures of SM.Results: CVLT-II SM impairment was significantly associated with increased errors on experimental SM measures and lower scores on measures of passage recall and executive functions, but not visuospatial skills. In a logistic regression controlling for clinicodemographic factors, CVLT-II SM impairment was a significant independent predictor of HAND, with the HAND + group showing higher rates of SM impairment than both the HAND - and HIV - groups. Finally, CVLT-II SM impairment was significantly related to a composite measure of everyday functioning, but this effect disappeared after adjusting for covariates. Note that, the overall pattern of findings across this study also held when CVLT-3 normative standards were applied to the SM indices.Conclusions: Results provide initial support for the construct and criterion validity of a CVLT-II SM index in the setting of HIV disease. Future studies should examine the validity of CVLT-II SM variables in other neuropsychological populations.


Assuntos
Testes de Memória e Aprendizagem/normas , Memória/fisiologia , Testes Neuropsicológicos/normas , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
20.
Appl Neuropsychol Adult ; 27(1): 82-86, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30183428

RESUMO

Performance Validity Testing has become an integral part of neuropsychological assessment, and a variety of embedded screening measures for performance validity have been proposed. Several performance validity indexes have been developed for the Repeatable Battery for the Assessment of Neuropsychological Status. Although the RBANS Effort Index (EI) and Effort Scale (ES) have garnered some empirical support, other research has raised questions regarding their accuracy in a number of assessment contexts. We evaluated the classification accuracy of the EI and ES against a standalone performance validity measure (Test of Memory Malingering; TOMM) in a mixed clinical patient sample. Our results showed limited utility for the ES in a mixed sample and modest classification accuracy for the EI, raising concerns about the appropriate scope of use for these scales in general clinical practice, which suggested that an alternate EI cutoff score of >0 may be most appropriate.


Assuntos
Disfunção Cognitiva/diagnóstico , Simulação de Doença/diagnóstico , Testes de Memória e Aprendizagem/normas , Testes Neuropsicológicos/normas , Psicometria/normas , Adulto , Feminino , Humanos , Masculino
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