RESUMO
A 12-year old Elo dog was presented with recurring symptoms of conjunctivitis in November 2019. A single whitish nematode was found upon inspection of the eye and identified as a Thelazia callipaeda male. The morphological identification of the eye worm was supported by analysis of a partial cytochrome c oxidase I (cox1) gene sequence. The dog lived in Lower Saxony, northwestern Germany, and had not visited regions known to be endemic for T. callipaeda. This suggests that a local transmission cycle of this zoonotic nematode may exist in Germany.
Assuntos
Doenças do Cão/parasitologia , Infecções por Spirurida/veterinária , Thelazioidea/isolamento & purificação , Animais , Doenças do Cão/transmissão , Cães , Complexo IV da Cadeia de Transporte de Elétrons/genética , Olho/parasitologia , Feminino , Alemanha , Proteínas de Helminto/genética , Masculino , Infecções por Spirurida/parasitologia , Infecções por Spirurida/transmissão , Thelazioidea/classificação , Thelazioidea/citologia , Thelazioidea/genéticaRESUMO
In this study, we describe a rare human case with corneal ulcer caused by thelaziosis in a 69-year-old man in Southwest China. A male nematode was discovered and removed from the patient's right eye with a long spicule and further identified by sequencing mitochondrial cox1 gene. The ophthalmologic and molecular biological evidence demonstrates the corneal ulcer caused by T. callipaeda infection, which is mainly distributed in Asian and European countries. Most T. callipaeda infections are emerged in the conjunctiva, leading to conjunctivitis. To the best knowledge of the authors, corneal ulcers caused by T. callipaeda have not been reported yet.
Assuntos
Úlcera da Córnea/parasitologia , Infecções por Spirurida/parasitologia , Thelazioidea/isolamento & purificação , Idoso , Animais , China , Túnica Conjuntiva/parasitologia , Genes de Helmintos/genética , Genes Mitocondriais/genética , Humanos , Masculino , Thelazioidea/citologia , Thelazioidea/genéticaRESUMO
BACKGROUND: Thelazia callipaeda is a zoonotic nematode that affects the eyes of domestic and wild animals, including dogs, cats and red foxes. This parasitic eye worm is transmitted by Phortica variegata, which is a zoophilic fruit fly spread in Europe. Two wild European rabbits (Oryctolagus cuniculus) found dead in north-eastern Portugal were submitted to necropsy. RESULTS: Both animals presented gross lesions compatible with haemorrhagic viral disease. Eye examination revealed the presence of six worms (three in each animal, on both eyes). Out of the six nematodes, five females and one male were morphologically and molecularly identified as T. callipaeda. CONCLUSIONS: This is the first report of T. callipaeda in wild rabbits from Portugal, which reveals a new host for this parasite in southern Europe and emphasizes the importance of including thelaziosis in the differential diagnosis of ocular alterations in both animals and humans from areas where the eye worm is endemic.
Assuntos
Drosophilidae/parasitologia , Infecções Oculares Parasitárias/veterinária , Insetos Vetores/parasitologia , Coelhos/parasitologia , Infecções por Spirurida/veterinária , Thelazioidea/isolamento & purificação , Animais , Animais Selvagens , Diagnóstico Diferencial , Olho/parasitologia , Infecções Oculares Parasitárias/diagnóstico , Infecções Oculares Parasitárias/parasitologia , Evolução Fatal , Feminino , Masculino , Portugal , Infecções por Spirurida/diagnóstico , Infecções por Spirurida/parasitologia , Thelazioidea/classificação , Thelazioidea/citologiaRESUMO
After Thelazia callipaeda infection in dogs and cats were reported in Spain, a human case of thelaziosis in this country was reported, suggesting zoonotic transmission. The active reproductive status of this nematode in situ indicates that humans are competent hosts for this parasite.
Assuntos
Infecções por Spirurida/parasitologia , Thelazioidea/isolamento & purificação , Zoonoses/parasitologia , Adolescente , Animais , DNA de Protozoário , Complexo IV da Cadeia de Transporte de Elétrons/genética , Infecções Oculares Parasitárias/diagnóstico , Infecções Oculares Parasitárias/parasitologia , Feminino , Humanos , Espanha , Infecções por Spirurida/diagnóstico , Infecções por Spirurida/transmissão , Thelazioidea/citologia , Thelazioidea/genética , Zoonoses/transmissãoRESUMO
An ocular Thelazia callipaeda infestation was found in a male domestic dog in Taiwan during regular examination. This is the first report of the parasite from pet animal in Taiwan. The infested dog showed normal bodily condition but slight conjunctival congestion. This parasite has been reported in humans in southeast Asia, China and Korea. In 1998, first human case was reported in the central area of Taiwan. The dogs infected with T. callipaeda may have important implication in the infestation of this parasite to humans as reservoir hosts.
