RESUMO
Congenital toxoplasmosis (CT) is a parasitic disease that causes serious fetal and neonatal harm or death. In countries that do not have antenatal screening programs, the initiation of CT treatment relies on a postnatal diagnosis. Until recently, diagnosis was based on clinical signs and immunoglobulin seropositivity, which is fraught with difficulty. In these cases, diagnosis was often delayed or treatment, which carries risk, started empirically. We highlight the use of polymerase chain reaction to diagnose a case of congenital toxoplasmosis, allowing early treatment and justifying the treatment burden.
Assuntos
DNA de Protozoário/sangue , DNA de Protozoário/líquido cefalorraquidiano , Reação em Cadeia da Polimerase/métodos , Toxoplasmose Congênita/diagnóstico , Toxoplasmose Ocular/diagnóstico , Antiprotozoários/uso terapêutico , Quimioterapia Combinada , Diagnóstico Precoce , Eletroencefalografia , Humanos , Lactente , Leucovorina/uso terapêutico , Imageamento por Ressonância Magnética , Masculino , Pirimetamina/uso terapêutico , Punção Espinal , Sulfadiazina/uso terapêutico , Tomografia Computadorizada por Raios X , Toxoplasmose Congênita/sangue , Toxoplasmose Congênita/líquido cefalorraquidiano , Toxoplasmose Congênita/tratamento farmacológico , Toxoplasmose Ocular/sangue , Toxoplasmose Ocular/líquido cefalorraquidiano , Toxoplasmose Ocular/tratamento farmacológico , UltrassonografiaRESUMO
A 32-year-old man suffered from juxtapapillary retinochoroiditis in the right eye and a psychiatric disorder. The diagnosis of toxoplasmosis was supported by the clinical ocular findings, serologic examinations, and isolation of the organism from the cerebrospinal fluid. As the retinochoroidal lesion absorbed, the psychiatric symptoms also disappeared during the course of six weeks.
