[A radioindicator method of determining the activity of pancreatic lipase in the body]. / Radioindikatorynyi metod opredeleniia aktivnosti pankreaticheskoi lipazy v organizme.

125I-p-iodophenyllaurate proved to be a suitable substrate of lipase for studies of pancreas lipolytic function in vivo and in vitro. After peroral administration into rats the drug was hydrolyzed by lipase. The liberated 125I-p-iodophenol was absorbed in intestine and excreted with urine either as free 125I-p-iodophenol or its conjugates. Activity of pancreatic lipase was measured on the basis of radioactivity estimation of urine per min.