RESUMO
Tuberculosis currently remains a serious medical problem, therefore increased attention is being paid to this disease. Paleopathological studies focused on the monitoring of morbid changes in skeletal remains of historical populations facilitate a detailed study of the development of this disease. They provide direct evidence of the existence of tuberculosis and its past forms. In addition to literary and iconographic sources, the present study is focused on recording the findings of bone tuberculosis in historical osteological sets from the Czech Lands and is the starting point for their detailed review. Approximately 76 cases of bone tuberculosis from the Czech Lands have been published and more or less reliably documented from 20 archeological sites dated back from the Eneolithic to the modern period.
Assuntos
Tuberculose Osteoarticular/história , Técnicas Bacteriológicas , República Tcheca/epidemiologia , Tchecoslováquia/epidemiologia , Feminino , História do Século XV , História do Século XVI , História do Século XVII , História do Século XVIII , História do Século XIX , História do Século XX , História do Século XXI , História Antiga , História Medieval , Humanos , Masculino , Mycobacterium tuberculosis/isolamento & purificação , Mycobacterium tuberculosis/patogenicidade , Paleopatologia , Prevalência , Vacinas contra a Tuberculose/história , Tuberculose Osteoarticular/epidemiologia , Tuberculose Osteoarticular/microbiologia , Tuberculose Osteoarticular/prevenção & controleRESUMO
No disponible
Assuntos
Feminino , Idoso , Idoso de 80 Anos ou mais , Humanos , Tenossinovite/diagnóstico , Tenossinovite/patologia , Tuberculose Osteoarticular/epidemiologia , Tuberculose Osteoarticular/prevenção & controle , Corticosteroides , Corticosteroides , Corticosteroides/toxicidade , Eletromiografia/métodos , Reação em Cadeia da PolimeraseRESUMO
Six patients with extra-pulmonary tuberculosis who presented within a 2-year period to the Paediatric Department of the Faculty of Medicine, Galle, Sri Lanka, are presented. In spite of the BCG vaccination being given to all of them at birth, five patients subsequently developed miliary tuberculosis and one patient bone tuberculosis. The likely reasons for failure of BCG vaccination to prevent extra-pulmonary complications developing are discussed.
Assuntos
Vacina BCG , Tuberculose Miliar/prevenção & controle , Tuberculose Osteoarticular/prevenção & controle , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Tuberculose Miliar/líquido cefalorraquidiano , Tuberculose Osteoarticular/líquido cefalorraquidianoRESUMO
Os autores apresentam 11 casos diagnosticados de tuberculose osteoarticular, sendo oito pacientes com acometimento da coluna vertebral, dois da articulaçäo coxofemoral e um do joelho. Verificou-se o acomentimento de um só local em todos os casos e em apenas dois pacientes havia referência a traumas anteriores à doença. O PPD foi näo-reator em três crianças do grupo, sendo reator forte nos demais. Os autores comentam, ainda, a alta freqüencia de tratamento cirúrgico nestes pacientes, que estaria provavelmente ligado ao diagnóstico tardio da doença
Assuntos
Criança , Masculino , Feminino , Quadril , Joelho , Tuberculose Osteoarticular/diagnóstico , Brasil , Técnicas de Laboratório Clínico , Teste Tuberculínico , Tuberculose Osteoarticular/prevenção & controle , Tuberculose da Coluna Vertebral/cirurgiaRESUMO
The protective effect of bacille Calmette-Guérin (BCG) vaccination against tuberculosis is controversial. In a study, 330 patients less than 12 years of age with tuberculosis, 52.1% of whom had had BCG vaccination, were compared with a control group of 1106 patients free of tuberculosis, 81% of whom had BCG vaccination. The occurrence of disseminated forms of tuberculosis, tuberculous meningitis, tuberculous peritonitis, and tuberculosis of bone and joints in BCG-vaccinated patients was quite low. With BCG vaccination, the incidence of the disseminated form of tuberculosis was significantly lower than that of pulmonary tuberculosis with pulmonary parenchymal lesions, primary pulmonary complexes, and pleural effusion. Tuberculous peritonitis was significantly less frequent than pulmonary tuberculosis with pulmonary parenchymal lesions, enlarged hilar glands, pulmonary primary complex, and pleural effusions. The study demonstrated that BCG gave an overall protective effect of 74% and that a major effect of this immunity was to produce a localized form of tuberculosis.
