First description of basaloid carcinoma of the canine mammary gland: case report / Primeira descrição do carcinoma basaloide da glândula mamária canina: relato de caso
Arq. bras. med. vet. zootec. (Online)
; 71(3): 878-882, May-June 2019. tab, ilus
Article
in En
| VETINDEX, LILACS
| ID: biblio-1011306
Responsible library:
BR68.1
Localization: BR68.1
ABSTRACT
The objective of this case report was to describe histopathological and immunohistochemical characteristics of the first reported basaloid carcinomas in the canine mammary gland. Two bitches were treated for tumors in the mammary gland and underwent mastectomy. Microscopic evaluation of these tumors revealed epithelial cells arranged in a predominantly solid pattern with hyperchromatic peripheral cells arranged in a palisade pattern. Metastases in regional lymph nodes were found in both animals, and one bitch exhibited pulmonary metastasis. Immunohistochemistry revealed positive labeling for the basal cell markers cytokeratin 14 and p63. Histopathological and immunohistochemical findings led to diagnoses of basaloid carcinoma of the canine mammary gland with regional and distant metastasis.(AU)
RESUMO
O objetivo deste relato de caso é descrever as características histopatológicas e imuno-histoquímicas do primeiro relato de carcinoma basaloide na glândula mamária canina. Duas cadelas foram atendidas com tumores na glândula mamária e foram submetidas à mastectomia. A avaliação microscópica demonstrou células epiteliais arranjadas em um padrão predominantemente sólido, com células periféricas hipercromáticas, dispostas em paliçada. As duas apresentaram metástase em linfonodos regionais e uma delas metástase pulmonar. A imuno-histoquímica revelou marcação positiva para citoqueratina 14 e p63, marcadores de células basais. Achados histopatológicos e imuno-histoquímicos levaram ao diagnóstico de carcinoma basaloide da glândula mamária canina com metástase regional e a distância.(AU)
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
/
VETINDEX
Main subject:
Carcinoma, Squamous Cell
/
Adenocarcinoma
/
Mammary Neoplasms, Animal
Limits:
Animals
Language:
En
Journal:
Arq. bras. med. vet. zootec. (Online)
Journal subject:
Medicina Veterin ria
Year:
2019
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil