Relationship between acetaldehyde concentration in mouth air and characteristics of microbiota of tongue dorsum in Japanese healthy adults: a cross-sectional study
J. appl. oral sci
; 27: e20180635, 2019. tab, graf
Article
in English
| LILACS, BBO - Dentistry
| ID: biblio-1012524
Responsible library:
BR1.1
ABSTRACT
Abstract Acetaldehyde, associated with consumption of alcoholic beverages, is known to be a carcinogen and to be related to the tongue dorsum. Objective The aim of this study was to investigate the relationship between acetaldehyde concentration in mouth air and bacterial characteristics on the tongue dorsum. Methodology Thirty-nine healthy volunteers participated in the study. Acetaldehyde concentrations in mouth air were evaluated by a high-sensitivity semiconductor gas sensor. A 16S rRNA gene sequencing technique was used to compare microbiomes between two groups, focusing on the six samples with the highest acetaldehyde concentrations (HG) and the six samples with lowest acetaldehyde concentrations (LG). Results Acetaldehyde concentration increased in correlation with the increase in bacterial count (p=0.048). The number of species observed in the oral microbiome of the HG was higher than that in the oral microbiome of the LG (p=0.011). The relative abundances of Gemella sanguinis, Veillonella parvula and Neisseria flavescens in the oral microbiome of the HG were higher than those in the oral microbiome of the LG (p<0.05). Conclusion Acetaldehyde concentration in mouth air was associated with bacterial count, diversity of microbiome, and relative abundance of G. sanguinis, V. parvula, and N. flavescens.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Leprosy
Database:
BBO - Dentistry
/
LILACS
Main subject:
Tongue
/
Microbiota
/
Acetaldehyde
/
Mouth
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2019
Document type:
Article
Affiliation country:
Japan
Institution/Affiliation country:
National Hospital Organization Hokkaido Cancer Center/JP
/
Okayama University Hospital/JP
/
Okayama University/JP