Etanercept in erythema nodosum leprosum
An. bras. dermatol
; 92(4): 575-577, July-Aug. 2017. graf
Article
in English
| LILACS
| ID: biblio-1038255
Responsible library:
BR1.1
ABSTRACT
Abstract One of the biggest challenges in treating leprosy is the control of reaction events. Patients with lepromatous leprosy may present reaction type II, or erythema nodosum leprosum, during treatment, and this reaction can remain in a recurrent form after being released from the hospital, requiring the use of thalidomide and/or prednisone for long periods of time, in turn increasing the risk of side effects. Two reports of the use of antiTNF to treat erythema nodosum leprosum were found in the literature. A good response was found after an assay with infliximab and etanercept. This study reports on a patient with lepromatous leprosy and recurrent reaction, controlled by using etanercept and a 10-month follow-up, with the interruption of thalidomide and the maintenance of prednisone at 10 mg/day.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Leprosy
/
Neglected Diseases
Database:
LILACS
Main subject:
Leprosy, Lepromatous
/
Anti-Inflammatory Agents, Non-Steroidal
/
Erythema Nodosum
/
Etanercept
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2017
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Santa Casa de Misericórdia do Rio de Janeiro/BR