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Volumen plaquetario medio, índice de neutrófilos/linfocitos e índice de trombocitos/linfocitos para determinar el diagnóstico y/o pronóstico en niños con mordedura de serpiente / Mean platelet volume, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in determining the diagnosis or outcome in children with snakebite
Aktar, Fesih; Tekin, Recep.
Affiliation
  • Aktar, Fesih; Dicle University. Facultad de Medicina. Departamento de Enfermedades Infecciosas Pediátricas. Diyarbakir. TR
  • Tekin, Recep; Dicle University. Facultad de Medicina. Departamento de Enfermedades Infecciosas y Microbiología Clínica. Diyarbakir. TR
Arch. argent. pediatr ; 115(6): 576-580, dic. 2017. tab
Article in English, Spanish | LILACS, BINACIS | ID: biblio-1038392
Responsible library: AR94.1
RESUMEN
Objetivo.Evaluar la relación entre las variables de volumen plaquetario medio (VPM), índice de neutrófilos/linfocitos (INL) e índice de trombocitos/linfocitos (ITL) y el diagnóstico o la predicción del desenlace en los niños con intoxicación por mordedura de serpiente. Métodos.Se realizó una evaluación retrospectiva de niños con diagnóstico de intoxicación por mordedura de serpiente y un grupo de referencia de sujetos sanos. Se clasificó a los pacientes en tres grupos de intoxicación leve, moderada y grave. Resultados.Se incluyeron 142 niños en el estudio. La leucocitosis (p= 0, 003), la neutrofilia (p= 0, 026) y la trombocitopenia (p= 0, 034) fueron significativamente más frecuentes en los casos de intoxicación por mordedura de serpiente grave; sin embargo, no se hallaron diferencias estadísticamente significativas en relación con el VPM, el INL y el ITL entre los diferentes grupos de intoxicación por mordedura de serpiente. La media del VPM, el INL y el ITL era significativamente mayor entre los niños con mordedura de serpiente en comparación con los controles sanos. Conclusiones.Según nuestros resultados, el uso del VPM, el INL y el ITL podría servir para el diagnóstico como marcadores inflamatorios en los casos de intoxicación por mordedura de serpiente.
ABSTRACT

Background:

The objective of this study is to evaluate the relationships between the mean platelet volume (MPV), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) variables and diagnosis or prediction of outcome in children with snakebite envenomation.

Methods:

Children diagnosed with snakebite envenomation and a control group of healthy subjects were retrospectively evaluated. Patients were classified into three groups as mild, moderate and severe.

Results:

142 children were enrolled in the study. Leukocytosis (p= 0.003), neutrophilia (p= 0.026) and thrombocytopenia (p= 0.034) were significantly more common in severe snakebite envenomation, although no statistical significant were found in association with MPV, NLR and PLR between snakebite envenomation groups. The mean MPV, NLR and PLR were found to be significantly higher in children with snakebite compared to than among healthy controls.

Conclusions:

Our results suggested that MPV, NLR and PLR may be useful for the diagnosis as inflammatory markers in snakebite envenomation.
Subject(s)


Full text: Available Collection: International databases Health context: Neglected Diseases Health problem: Zoonoses Database: BINACIS / LILACS Main subject: Poisoning / Snakes / Blood Platelets / Lymphocytes / Child / Index / Mean Platelet Volume / Neutrophils Type of study: Diagnostic study / Prognostic study Limits: Adolescent / Child / Child, preschool / Humans Language: English / Spanish Journal: Arch. argent. pediatr Journal subject: Pediatrics Year: 2017 Document type: Article Affiliation country: Turkey Institution/Affiliation country: Dicle University/TR

Full text: Available Collection: International databases Health context: Neglected Diseases Health problem: Zoonoses Database: BINACIS / LILACS Main subject: Poisoning / Snakes / Blood Platelets / Lymphocytes / Child / Index / Mean Platelet Volume / Neutrophils Type of study: Diagnostic study / Prognostic study Limits: Adolescent / Child / Child, preschool / Humans Language: English / Spanish Journal: Arch. argent. pediatr Journal subject: Pediatrics Year: 2017 Document type: Article Affiliation country: Turkey Institution/Affiliation country: Dicle University/TR
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