Alterations induced in the ileum of mice upon inoculation with different species of Leishmania: a preliminary study
Rev. Soc. Bras. Med. Trop
; 51(4): 537-541, July-Aug. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-1041471
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Leishmania species cause skin, mucosal, and disseminated lesions. We studied the effects of three Leishmania species on ileal morphology in mice.METHODS:
BALB/c mice were intraperitoneally inoculated with Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) major (4 animals/group). After 72h, the ilea were collected and histologically processed.RESULTS:
Following inoculation, the goblet cell and intraepithelial lymphocyte populations increased, while Paneth cell number and crypt width decreased. In addition, enterocyte size, villi height, and mucosa, submucosa, and muscular tunic thickness increased.CONCLUSIONS:
Leishmania modified the quantity of cells in and morphology of mice ilea.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Zoonoses
Database:
LILACS
Main subject:
Leishmaniasis
/
Ileum
/
Leishmania
/
Mice
Limits:
Animals
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2018
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual de Maringá/BR