In vitro antifungal susceptibility of Candida speciesisolated from diabetic patients
Rev. Soc. Bras. Med. Trop
; 51(4): 542-545, July-Aug. 2018. tab
Article
in English
| LILACS
| ID: biblio-1041473
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION This study aims to evaluate the antifungal susceptibility of different species of Candida isolated from diabetic patients against eight antifungal agents. METHODS Susceptibility testing of 111 clinical isolates of Candida species was performed against 8 antifungals using the M27-A3 protocol of the Clinical and Laboratory Standards Institute (CLSI). RESULTS Voriconazole, lanoconazole, and caspofungin showed the highest in vitro activity against all the isolates of C. albicans. Resistance against the tested antifungals was only observed in the C. albicans isolates. CONCLUSIONS Our finding revealed that resistance against amphotericin B, itraconazole, ketoconazole, posaconazole, and fluconazole can be observed in C. albicans.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Candida
/
Diabetes Mellitus
/
Antifungal Agents
Type of study:
Practice guideline
Limits:
Adult
/
Aged
/
Aged, 80 and over
/
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2018
Document type:
Article
Affiliation country:
Iran
Institution/Affiliation country:
Babol University of Medical Sciences/IR
/
Islamic Azad University/IR
/
Mazandaran University of Medical Sciences/IR
/
Shahid Beheshti University of Medical Sciences/IR
/
Social Security Administration of Amole/IR