Experimental models of scald burns. A scope review
Acta cir. bras
; 34(10): e201901007, Oct. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1054673
Responsible library:
BR1.1
ABSTRACT
Abstract Purpose:
To conduct a scope review of the experimental model described by Walker and Mason, by identifying and analyzing the details of the method.Methods:
The authors searched Pubmed-Medline, Cochrane-Bireme and PEDro databases for articles published between January 2016 and December 2018, using the following search queries burns, burn injuries, models animal, and animal experimentation. All articles whose authors used Walker and Mason's model - with or without changes to the method in Wistar rats - were included in this study.Results:
The search identified 45 mentions of Walker and Mason's model; however, after reading each summary, 20 were excluded (of which 5 due to duplicity). The inconsistencies observed after the scope review were water temperature, length of time of exposure of the experimental model's skin to water, extent of the burnt area, and the description of the thickness/depth of the injury.Conclusions:
Reproducibility of a scientific method is the basis to prove the veracity of the observed results. Thus, it is necessary to have a greater number of publications that adopt a reproducible scientific method, for this review found inconsistencies in the description of Walker and Mason's model.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Burns
/
Disease Models, Animal
/
Hot Temperature
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2019
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UNIFESP/BR
/
Universidade Santo Amaro/BR