Investigation of carbapenemases and aminoglycoside modifying enzymes of Acinetobacter baumannii isolates recovered from patients admitted to intensive care units in a tertiary-care hospital in Brazil
Rev. Soc. Bras. Med. Trop
; 53: e20190044, 2020. tab
Article
in English
| LILACS
| ID: biblio-1057279
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Acinetobacter baumannii are opportunistic bacteria, highly capable of acquiring antimicrobial resistance through the production of carbapenemases and aminoglycoside modifying enzymes (AMEs).METHODS:
Carbapenemase and AME genes were investigated in A. baumannii recovered from inpatients of a Brazilian hospital.RESULTS:
The key genes found were bla OXA-51-like, the association ISAba1- bla OXA-23-like, and the AME genes aph(3´)-VI, aac(6´)-Ib, aac(3)-Ia, and aph(3´)-Ia. Different clusters spread through the institution wards.CONCLUSIONS:
The dissemination of bla OXA-23-like and AME-carrying A. baumannii through the hospital highlights the need for improved preventive measures to reduce the spread of infection.
Full text:
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Collection:
International databases
Database:
LILACS
Main subject:
Bacterial Proteins
/
Beta-Lactamases
/
Acinetobacter Infections
/
Acinetobacter baumannii
/
Aminoglycosides
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2020
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Faculdade de Medicina de São José do Rio Preto/BR
/
Instituto Adolfo Lutz/BR
/
Universidade Federal de São Carlos/BR